Panama City, FL Office Properties & Spaces for Rent & Lease

$21 SF/Yr

1,906 SF

Downtown Panama City Office Space

455 Harrison Ave, Panama City, FL 32401

Professional office space in downtown Panama City for lease.

Prime Downtown Panama City location on Harrison Avenue.
1906 sq ft of professional office space.
Well‑maintained: Rebuilt in the early 2000s and consistently occupied since.
Includes a large executive office, two senior level offices, three staff offices, and a conference room.
Features two accessible bathrooms and a breakroom.

Updated: Feb 12

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$2,500 / Mo

1,903 SF

Panama City Office Space Available

309 E 7Th St, Panama City, FL 32401

Well-located office building ideal for small businesses or professional services.

Ready for immediate occupancy, allowing for a quick business setup.
Ideal for various business types: small businesses, medical, or professional services.
Functional layout includes 4 private offices, reception area, full bathroom, and kitchen/break area.
Convenient location with easy access to major roads, local businesses, and amenities.
Clean and modern office building.

Updated: Dec 21, 2025

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$4,000 / Mo

8,376 SF

Downtown Panama City Commercial Space

Rare 3,000 SF commercial space for lease on Harrison Ave.

602 Harrison Ave, Panama City, FL 32401

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$3,500 / Mo

6,500 SF

Versatile Commercial Space Off Highway

Flexible leasing options near Highway 231, ideal for various businesses.

6804 Bayou George Dr, Panama City, FL 32404

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$5,000 / Mo

Versatile Office and Warehouse Space

Versatile office and warehouse space in an ideal location.

1337 W 19Th St, Panama City, FL 32405

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$18 SF/Yr

2,801 SF

Medical Office Space For Rent

Well-designed medical office space with excellent visibility and convenient access.

2420 Jenks Ave, Panama City, FL 32405

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$16 SF/Yr

4,845 SF

Professional Office Building For Rent

Functional office space in Panama City's business district.

833 Harrison Ave, Panama City, FL 32401

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$15 SF/Yr

2,700 SF

Downtown Panama City Commercial Space

Versatile commercial space in historic downtown Panama City with parking.

416 Jenks Ave, Panama City, FL 32401

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$13 SF/Yr

7,200 SF

Panama City Flex Warehouse

7,200 SF flex warehouse in Panama City for lease.

1117 Saint Andrews Blvd, Panama City, FL 32405

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$20 SF/Yr

3,616 SF

Turnkey Medical Office Building

Move-in ready medical office near hospitals with ample parking.

2624 Jenks Ave, Panama City, FL 32405

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$25 SF/Yr

2,783 SF

Turnkey Medical Office Space Available

Equipped medical office suite with X-ray, ready for practice.

2426 Jenks Ave, Panama City, FL 32405

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Versatile Multi-Tenant Building For Lease

Contact for pricing

5,000 SF

Versatile Multi-Tenant Building For Lease

Multi-tenant building with flexible space options and strategic location.

501 West 11Th St, Panama City, FL 32401

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$2,500 / Mo

2,000 SF

Remodeled Retail and Office Space

2,000 SF remodeled space suitable for retail or office.

748 E 15Th St, Panama City, FL 32401

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$25 SF/Yr

2,921 SF

Medical Office Space Available

Turnkey medical office space with exam rooms and offices.

603 Frederick St, Panama City, FL 32405

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$26 SF/Yr

1,522 SF

Office Space in Town Centre

4,500 SF office suite with multiple offices and amenities.

101 W 5Th St, Panama City, FL 32401

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$10,000 / Mo

15,000 SF

Panama City Office Space

Office space available for lease in Panama City, Florida.

1502 Tennessee Ave, Panama City, FL

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$3,950,000

1,532 SF

Medical Office Suites For Rent

Medical office suites available in a prominent medical core location.

1600 Jenks Ave, Panama City, FL 32405

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$2,400,000

20,000 SF

Versatile Panama City Office Asset

20,000 SF office building with flexible floorplate and ample parking.

230 N Tyndall Pkwy, Panama City, FL 32404

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Customizable Office/Flex Space Available

Contact for pricing

7,500 SF

Customizable Office/Flex Space Available

Versatile office/flex space for lease with highway frontage.

2830 Highway 390 East, Panama City, FL 32405

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$20 SF/Yr

9,999 SF

Panama City Office Space

Office space available for lease in Panama City, Florida.

510 N Macarthur Ave, Panama City, FL 32401

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Renovated Commercial Building Near Tyndall AFB

$16 SF/Yr

4,004 SF

Renovated Commercial Building Near Tyndall AFB

Versatile 4,004 SF building suitable for daycare or professional uses.

5311 Highway 22 E, Panama City, FL 32404

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$13 SF/Yr

Office Building Near Navy Base

8,000 SF office building near Navy Base main gate.

520 Skyview Dr, Panama City, FL 32408

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$14 SF/Yr

Flex Building with Office, Warehouse

Flex building featuring office and warehouse space for lease.

7622 Mc Elvey Rd, Panama City, FL 32408

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$1,146 / Mo

24,852 SF

Class A Office Space Available

First floor office space with utilities included, convenient location.

2605 Thomas Dr, Panama City, FL 32408

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Panama City, FL Office Properties & Spaces Leasing Opportunities Market Analysis

Explore Office Properties & Spaces leasing options in Panama City, FL with 121 listings featured on our commercial real estate exchange. The current inventory includes 66,613,650,840 square feet of properties with an estimated lease value of $1,066 /Mo.

Estimated lease rates for Office Properties & Spaces in Panama City, FL begin at $0.55 SF/Yr, with an average of $17 SF/Yr and extend to $44 SF/Yr.

Panama City, FL Office Properties & Spaces for Lease

Downtown Panama City Office Space

Professional office space in downtown Panama City for lease.

Panama City Office Space Available

Well-located office building ideal for small businesses or professional services.

Downtown Panama City Commercial Space

Versatile Commercial Space Off Highway

Versatile Office and Warehouse Space

Medical Office Space For Rent

Professional Office Building For Rent

Downtown Panama City Commercial Space

Panama City Flex Warehouse

Turnkey Medical Office Building

Turnkey Medical Office Space Available

Versatile Multi-Tenant Building For Lease

Remodeled Retail and Office Space

Medical Office Space Available

Office Space in Town Centre

Panama City Office Space

Medical Office Suites For Rent

Versatile Panama City Office Asset

Customizable Office/Flex Space Available

Panama City Office Space

Renovated Commercial Building Near Tyndall AFB

Office Building Near Navy Base

Flex Building with Office, Warehouse

Class A Office Space Available

Panama City, FL Office Properties & Spaces Leasing Opportunities Market Analysis

Browse Office Properties & Spaces for Lease Near Panama City, FL

Popular Searches in Panama City, FL

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Panama City, FL Office Properties & Spaces for Lease

Downtown Panama City Office Space

Professional office space in downtown Panama City for lease.

Panama City Office Space Available

Well-located office building ideal for small businesses or professional services.

Downtown Panama City Commercial Space

Versatile Commercial Space Off Highway

Versatile Office and Warehouse Space

Medical Office Space For Rent

Professional Office Building For Rent

Downtown Panama City Commercial Space

Panama City Flex Warehouse

Turnkey Medical Office Building

Turnkey Medical Office Space Available

Versatile Multi-Tenant Building For Lease

Remodeled Retail and Office Space

Medical Office Space Available

Office Space in Town Centre

Panama City Office Space

Medical Office Suites For Rent

Versatile Panama City Office Asset

Customizable Office/Flex Space Available

Panama City Office Space

Renovated Commercial Building Near Tyndall AFB

Office Building Near Navy Base

Flex Building with Office, Warehouse

Class A Office Space Available

Panama City, FL Office Properties & Spaces Leasing Opportunities Market Analysis

Browse Office Properties & Spaces for Lease Near Panama City, FL

Popular Searches in Panama City, FL

Popular Categories

Most Searched ZIP Codes in Panama City, FL

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