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    Panama City, FL Office Properties & Spaces for Lease

    88 results
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    Panama City Office Space Available
    $15 SF/Yr

    Panama City Office Space Available

    5620 Cherry St Unit, Panama City, FL 32404

    Vanilla shell office space in a first-class building.

    • Vanilla Shell space allows for custom interior design.
    • Located in a first‑class office building.
    • Excellent location off Cherry St. and Hwy 98.
    • Central and Electric Heating.
    • Accessible Approach with Ramp.
    Updated: Dec 30, 2025
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    Versatile Commercial Space Near Highway
    $3,500 / Mo

    Versatile Commercial Space Near Highway

    6804 Bayou George Dr, Panama City, FL 32404

    Flexible leasing options ideal for various business needs.

    • Prime location directly off high‑traffic US Highway 231, offering excellent visibility and easy access.
    • Versatile commercial space suitable for contractors, service providers, small business offices, or satellite operations.
    • Choose a configuration of 1‑3 private offices to suit specific business needs.
    • Includes access to a well‑equipped conference room, kitchen, and welcoming waiting area.
    • Large grassy area available for storage or staging of equipment, trailers, or other business assets.
    Updated: Dec 2, 2025
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    Downtown Panama City Office Space
    $21 SF/Yr

    Downtown Panama City Office Space

    Professional office space in downtown Panama City for rent.

    455 Harrison Ave, Panama City, FL 32401
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    Modern Office Space, Highway Access
    Pending
    $2,400 / Mo

    Modern Office Space, Highway Access

    Modern office space with two private offices and storage.

    3213 Highway 98 W, Panama City, FL 32401
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    Panama City Office Space Available
    $2,500 / Mo

    Panama City Office Space Available

    Office building in Panama City, ready for immediate occupancy.

    309 E 7Th St, Panama City, FL 32401
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    Corner Lot Office Space
    Pending
    $2,850 / Mo

    Corner Lot Office Space

    Office space on corner lot with high visibility.

    5000 Highway 22 E, Panama City, FL 32404
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    Downtown Panama City Commercial Space
    $4,000 / Mo

    Downtown Panama City Commercial Space

    Rare commercial space for lease in downtown Panama City.

    602 Harrison Ave, Panama City, FL 32401
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    Professional Office Suites For Lease
    $675 / Mo

    Professional Office Suites For Lease

    Professional office suites available for lease near downtown Panama City.

    215 W 11Th St, Panama City, FL 32401
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    Warehouse and Office Space Available
    $16 SF/Yr

    Warehouse and Office Space Available

    Warehouse and office space for lease in Panama City, FL.

    1220 Transmitter Rd, Panama City, FL 32404
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    Panama City Commercial Warehouse For Rent
    Pending
    $3,000 / Mo

    Panama City Commercial Warehouse For Rent

    Versatile commercial space with warehouse, office, and ample parking.

    528 E 6Th St, Panama City, FL 32401
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    Spacious Panama City Medical Office
    Pending
    $19 SF/Yr
    7,650 SF

    Spacious Panama City Medical Office

    4,400 SF medical office space with nine exam rooms.

    2428 Jenks Ave Unit, Panama City, FL 32405
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    Medical Office Space For Rent
    Pending
    $19 SF/Yr
    3,250 SF

    Medical Office Space For Rent

    Spacious medical office buildout near 23rd St. on Jenks Ave.

    2428 Jenks Ave Unit, Panama City, FL 32405
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    Downtown Panama City Office Space
    $2,000 / Mo
    1,900 SF

    Downtown Panama City Office Space

    Office space in downtown Panama City with conference room.

    435 W Oak Ave, Panama City, FL 32401
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    Downtown Panama City Retail Opportunity
    Pending
    $3,500 / Mo

    Downtown Panama City Retail Opportunity

    2500 sq ft commercial space in downtown Panama City.

    27 Harrison Ave, Panama City, FL 32401
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    Panama City Warehouse and Office
    $8 SF/Yr
    4,000 SF

    Panama City Warehouse and Office

    Warehouse and office space available for lease in Panama City.

    1220 Transmitter Rd, Panama City, FL 32401
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    Prime Panama City Office Space
    $10,000 / Mo
    15,000 SF

    Prime Panama City Office Space

    15,000 SF Office, NNN Lease

    1502 Tennessee Ave, Panama City, FL 32444
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    Panama City Medical Office Suite
    $22 SF/Yr
    2,720 SF

    Panama City Medical Office Suite

    2720 SF Medical/Office Space, Prime Location

    221 East 23rd Street | Panama City, FL 32405, Panama City, FL 32405
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    Renovated Commercial Building Near Tyndall AFB
    $16 SF/Yr
    4,004 SF

    Renovated Commercial Building Near Tyndall AFB

    Versatile 4,004 SF building suitable for daycare or professional uses.

    5311 Highway 22 E, Panama City, FL 32404
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    Class A Office Space Available
    $25 SF/Yr
    24,852 SF

    Class A Office Space Available

    First floor office space with utilities included, central location.

    2605 Thomas Dr, Panama City, FL 32408
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    Renovated Office Space For Rent
    $12 SF/Yr
    65,955 SF

    Renovated Office Space For Rent

    Professional office space with flexible layout in high-visibility location.

    615 Highway 231, Panama City, FL 32405
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    Class A Office Space Available
    $1,146 / Mo
    24,852 SF

    Class A Office Space Available

    First floor office space with utilities included, convenient location.

    2605 Thomas Dr, Panama City, FL 32408
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    Medical Office Space Available
    $4,800 / Mo
    2,310 SF

    Medical Office Space Available

    Medical office space for rent featuring exam rooms and restrooms.

    2101 Northside Dr, Panama City, FL 32405
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    Downtown St Andrews Retail/Office Space
    $4,500 / Mo
    3,200 SF

    Downtown St Andrews Retail/Office Space

    3200 sq ft retail/office space in the heart of St Andrews.

    1107 Beck Ave, Panama City, FL 32401
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    Functional Office Building For Rent
    $16 SF/Yr
    4,845 SF

    Functional Office Building For Rent

    Professional office building in Panama City's business district.

    833 Harrison Ave, Panama City, FL 32401
    View details

    Panama City, FL Office Properties & Spaces Leasing Opportunities Market Analysis

    Explore Office Properties & Spaces leasing options in Panama City, FL with 127 listings featured on our commercial real estate exchange. The current inventory includes 66,946,449,240 square feet of properties with an estimated lease value of $3,110 /Mo.

    Estimated lease rates for Office Properties & Spaces in Panama City, FL begin at $0.55 SF/Yr, with an average of $48 SF/Yr and extend to $2,000 /Mo.
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    Browse Office Properties & Spaces for Lease Near Panama City, FL

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    Most Searched ZIP Codes in Panama City, FL

    • 32405
    • 32401
    • 32404
    • 32408
    • 32413
    • 32444
    • 32461
    • 32407

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