Hannibal, MO Office buildings for sale

Hannibal Commercial Building on St. Mary's

$309,000

8,170 SF

Hannibal Commercial Building on St. Mary's

2903 Saint Marys Ave, Hannibal, MO 63401

Well-maintained commercial building with office/retail space and ample parking.

High visibility location on St. Mary's Ave, near McMaster's traffic.
Boasting over 4,000 sqft of finished office/retail space.
Additional 4,000+ sqft basement for storage or expansion with garage door access.
Two separate office suites with independent access.
Private concrete parking pad with ample parking spots, plus additional rear parking.

Updated: Nov 18, 2025

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Updated Commercial Building with Billboard

$599,000

4,336 SF

Updated Commercial Building with Billboard

1329 Broadway, Hannibal, MO 63401

High-visibility commercial building with income potential in Hannibal, Missouri.

High‑performance digital billboard generating $3,100/month with significant income upside (up to 64 ads).
High‑visibility location on a major traffic corridor.
Fully updated and move‑in ready condition.
Versatile office space with new Central AC and forced air gas furnace.
72'x24' concrete parking lot with 6 dedicated spaces.

Updated: Oct 2, 2025

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$1,750,000

24,030 SF

Versatile Building in Hannibal, MO

24,030 SF building with flexible space and ample parking.

3201 Palmyra Rd, Hannibal, MO 63401

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Based on your search, we've compiled 7 Potential Opportunities for your consideration. Besides 3 Active listings in Hannibal, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities

Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

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15,500 SF

Class A Office Building

Leased Class A office building near BJC Hospital.

115 Piper Hill Dr, St Peters, MO 63376

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Saint Charles Office/Flex Building

Class A office/flex building in a prime Saint Charles location.

500 Fountain Lakes Blvd, Saint Charles, MO 63301

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53,932 SF

Class A Office/Flex Building

Office/flex building with heavy power and potential for warehouse conversion.

500 Fountain Lakes Blvd, Saint Charles, MO 63301

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7,819 SF

St. Peters Office Building For Sale

7,819 SF office building on 2.6 acres in St. Peters.

4189 Veterans Memorial Pkwy, St Peters, MO 63376

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Hannibal, MO Office Buildings Investment Opportunities Market Analysis

Explore 3 office buildings for sale in Hannibal, MO, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 409,028 square feet of properties for sale, with an estimated market value of $2,658,000.

Sale prices for office properties in Hannibal, MO start at $309,000, averaging $886,000, and reaching up to $1,750,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

Hannibal, MO Office Buildings for Sale

Hannibal Commercial Building on St. Mary's

Well-maintained commercial building with office/retail space and ample parking.