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Collin County, TX Medical Space for Lease

15 results
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Modern Medical Office in Frisco
$30 SF/Yr
186,611 SF

Modern Medical Office in Frisco

16100 State Hwy 121 Hwy S, Frisco, TX 75035

3,106 SF medical office space available for sublease or assignment.

  • Prime location off the highway in Frisco, at the crossroads of Frisco, McKinney, Plano, and Allen, offering high visibility and easy access.
  • Fully built‑out, modern 3,106 sq ft medical office space, ready for immediate use.
  • Equipped with 9 exam rooms/office spaces, break room, 2 bathrooms, shower, and digital x‑ray room with lead walls.
  • Opportunity for subleasing or lease assignment, suitable for various medical professionals.
  • Welcoming waiting area with amenities like water and coffee for patients.
Updated: Jan 10
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Shell Building For Lease/Sale
$40 SF/Yr
19,998 SF

Shell Building For Lease/Sale

5301 Alma Rd, McKinney, TX 75070

Shell building suitable for retail, office, or medical use.

  • Prime location in a fast‑growing corridor with exceptional visibility.
  • Modern shell construction ready for customization with flexible build‑out options.
  • Competitive sale and lease terms: $40/sq ft (NNN) to lease, $500/sq ft for purchase.
  • Flexible square footage available to customize.
  • Ample parking and convenient access to major thoroughfares.
Updated: Dec 20, 2025
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Medical Office Space Near Hospital
Contact for pricing
4,754 SF

Medical Office Space Near Hospital

Class A medical office space near Texas Health Presbyterian.

8196 Walnut Hill Ln, Dallas, TX 75231
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Medical Space in Preston Park
Contact for pricing
5,057 SF

Medical Space in Preston Park

Located in Plano, Texas, with retail and restaurant proximity.

4701 Old Shepard Pl, Plano, TX 75093
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Freestanding Building on Davis Street
Contact for pricing
2,040 SF

Freestanding Building on Davis Street

Highly visible building ideal for retail, medical, or creative space.

700 W Davis St, Dallas, TX 75208
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Medical Space Near Children's Hospital
Contact for pricing
2,800 SF

Medical Space Near Children's Hospital

Second-generation medical space in a professional complex near hospital.

7705-7707 San Jacinto Pl, Plano, TX 75024
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Medical ASC with Operating Rooms
Contact for pricing
5,850 SF

Medical ASC with Operating Rooms

Vacant medical ASC with operating rooms in Uptown Dallas.

4103 Swiss Ave, Dallas, TX 75204
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Retail/Medical Space For Lease
Contact for pricing
2,400 SF

Retail/Medical Space For Lease

Retail and medical spaces available with excellent visibility and access.

1855 Dallas Pkwy, Plano, TX 75093
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Freestanding Building for Lease
Contact for pricing
5,148 SF

Freestanding Building for Lease

5,148 sqft freestanding building suitable for retail, bar, or medical.

5605 E Grand Ave, Dallas, TX 75223
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Modern Medical Office in Frisco
$30 SF/Yr

Modern Medical Office in Frisco

3,106 SF medical office space available for sublease/assignment.

16100 State Highway 121, Frisco, TX 75035
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Premium Corner Retail/Office Space
Contact for pricing

Premium Corner Retail/Office Space

Move-in ready corner space serving 10,000+ households off 75.

5895 Trinity Falls Pkwy, McKinney, TX 75071
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Shops at Creekside Retail Center
Contact for pricing
12,500 SF

Shops at Creekside Retail Center

Frisco retail space, multiple suites available

13030 Preston Rd, Frisco, TX 75035
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Princeton Retail Space Available
$41 SF/Yr
3,500 SF

Princeton Retail Space Available

Medical Retail Space in Collin County, TX

1530 Princeton Dr, Princeton, TX 75407
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Lavon Retail Center: Prime Location
Contact for pricing
12,350 SF

Lavon Retail Center: Prime Location

New Retail/Restaurant Space Available in Lavon, TX

9930 State Highway 78, Lavon, TX 75166
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Frisco Lakes Retail Center
$31 SF/Yr
24,300 SF

Frisco Lakes Retail Center

New Retail Space Available - Frisco, TX

8275 Judges Way, Frisco, TX 75036
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Based on your search, we've compiled 17 Potential Opportunities for your consideration. Besides 15 Active listings in Collin County, TX, we suggest exploring alternatives. Similar 2 Properties for Sales.

Explore Similar Spaces for Sale in Collin County, TX

Consider Similar Space for Sale. We found 2 Spaces in Nearby Locations matching your search parameters.

Turnkey Furnished Office Showroom Space
$999,000

Turnkey Furnished Office Showroom Space

Furnished office showroom in medical district with rooftop deck.

4763 Algiers St, Dallas, TX 75207
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Versatile McKinney Commercial Property
$5,000,000

Versatile McKinney Commercial Property

Freestanding building suitable for offices, medical, retail, and more.

1450 Redbud Blvd, McKinney, TX 75069
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Collin County, TX Medical space Leasing Opportunities Market Analysis

Explore Medical space leasing options in Collin County, TX with 17 listings featured on our commercial real estate exchange. The current inventory includes 10,210,875,353 square feet of properties with an estimated lease value of $142 SF/Yr.

Estimated lease rates for Medical space in Collin County, TX begin at $30 SF/Yr, with an average of $35 SF/Yr and extend to $41 SF/Yr.
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