Commercial Real Estate Market in Defiance, MO
Updated monthly: sale, lease, property records, location trend, and more… · Last update: August 31
14 active listings and 52 off-market properties in Defiance, MO.
Market Trends
Defiance, MO spans 38.8 square miles in St. Charles County, Missouri. Figures below refresh monthly; last updated 31 August 2026.
Office
Office vacancy in Defiance, MO runs 21.3% across the Midwest region in 2025, up from 13.7% in 2019.
Vacancy Rate % in Midwest region
Retail
Retail vacancy in Defiance, MO runs 6.3% across the Midwest region in 2025, down from 8% in 2020.
Vacancy Rate % in Midwest region
Industrial
Industrial vacancy in Defiance, MO runs 4.9% across the Midwest region in 2025, up from 4.4% in 2019. Nearly 1.6x the 2022 low of 3.1%.
Vacancy Rate % in Midwest region
Multifamily
Multifamily vacancy in Defiance, MO runs 8% across the Midwest region in 2025, up from 6.5% in 2022.
Vacancy Rate % in Midwest region
Market overview
Demographics & Economy
Defiance, MO has 3,784 residents in 1,372 households. Density runs 97 people per square mile. Median household income here is $177,583 and median gross rent $1,086 a month.
3,784
Population
1,372
Households
2.8
Avg Household Size
50
Median Age
54%
College-Educated
98%
High-School Grad
38.8 sq mi
ZIP Area
97
Density / Sq Mi
$177,583
Median Household Income
$89,773
Median Earnings
$1,086
Median Rent
$552,600
Median Home Value
Tools
Nearby Markets
| Market | Average Sale Price, $/SF | Average Lease Price, $/SF/Yr |
|---|---|---|
| Matson | — | — |
| Saint Albans | — | — |
| Schluersburg | — | — |
| Wildwood | $100 (county avg) | — |
Commercial property in Defiance, MO asks $2/SF. That compares with $100/SF in Wildwood.
Frequently Asked Questions
What is the average price per square foot for commercial property in Defiance?
Commercial property in Defiance, MO asks an average of $2 per square foot.
How does Defiance compare to nearby markets on price?
Defiance, MO asks $2/SF against $100/SF in Wildwood.
Methodology & data sources
- Asking prices and averages
- Computed from 14 active for-sale and 0 active for-lease listings in Defiance, MO. These are ASKING figures from live listings, not closed-transaction prices, and a segment carried by a handful of listings reads as indicative rather than an average.
- Vacancy rates
- Published per-sector market series, taken at the metro level where one exists and otherwise at the Census-region level — a chart reading "in <region> region" is a regional number, not this city's.
- Refresh
- The monthly aggregates close at the end of the previous month, so 31 August 2026 — not today — is the honest last update.
- Known limitations
- office vacancy is reported at Midwest region level, retail vacancy is reported at Midwest region level and industrial vacancy is reported at Midwest region level.
- Coverage
- Metrics below the 10-observation threshold fall back one geographic level. The geography used is named on each figure.
Compiled by the Realmo Data team · reviewed 31 August 2026 · report a data issue
