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Independence, MO Commercial Real Estate for Lease

58 results
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Move-in Ready Commercial Spaces Available
$19 SF/Yr
69,696 SF

Move-in Ready Commercial Spaces Available

20101 E Jackson. Dr, Independence, MO 64057

Exceptional spaces for lease near I-70 and Independence Center.

  • Unbeatable location just north of Interstate 70 and one mile east of the I‑70/I‑470 interchange.
  • Move‑in‑ready spaces available: 1,146 sqft, 5,239 sqft, and a conjoining space of 2,749 sqft.
  • Easily accessible via the Little Blue Parkway exit ramp.
  • Proximity to Independence Center shopping district and major retailers within 1.5 miles.
  • Located near the Independence Events Center, drawing over 100 events per year.
Updated: Jan 30
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Flexible Commercial Space with Overhead Doors
$12 SF/Yr
14,810 SF

Flexible Commercial Space with Overhead Doors

17003 E Us 24 Hwy, Independence, MO 64056

Adaptable commercial space with open layout and convenient highway access.

  • Highly flexible +/-2,800 SF commercial space suitable for various businesses.
  • Five overhead doors provide efficient operations and easy equipment access.
  • Convenient highway access for customers and service vehicles.
  • Updated LED lighting throughout the space.
  • Includes 220V electrical service.
Updated: Jan 20
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Eastland Center Retail Space Available
$18 SF/Yr
213,444 SF

Eastland Center Retail Space Available

Prime retail space in high-traffic area near I-70 and MO-291.

18900 E Valley View Pkwy, Independence, MO 64055
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Medical Office Space Available
$1,900 / Mo
1,200 SF

Medical Office Space Available

2700 SF medical office with multiple exam/office rooms.

3800 S Elizabeth St, Independence, MO 64057
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Office Space Near I-70/I-470
Contact for pricing
2,616 SF

Office Space Near I-70/I-470

Centrally located office space with good highway visibility.

4721-4731 S Cliff Ave, Independence, MO 64055
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Retail Space with High Visibility
Contact for pricing
3,906 SF

Retail Space with High Visibility

Retail space available with excellent visibility and access.

17820 E 39Th St S, Independence, MO 64055
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Retail Space in Independence Heart
Contact for pricing
1,526 SF

Retail Space in Independence Heart

Retail space for lease in a high-traffic area.

1528 E 23Rd St S, Independence, MO 64055
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Retail Space on S. Noland
Contact for pricing
1,300 SF

Retail Space on S. Noland

Retail space with private office available March 1st, 2025.

1507 S Noland Rd, Independence, MO 64050
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Retail Space in High-Traffic Center
Contact for pricing
2,850 SF

Retail Space in High-Traffic Center

Retail space available in established shopping center with high visibility.

13500-13920 E 40Th St, Independence, MO 64055
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Retail Space on 39th Street
Contact for pricing
2,100 SF

Retail Space on 39th Street

2,100 SF retail space with excellent visibility on 39th Street.

3901 S Bolger Rd, Independence, MO 64055
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Retail Space Near Highway 291
Contact for pricing
2,622 SF

Retail Space Near Highway 291

Retail space near major retailers and high-traffic areas.

19210 E 39Th St S, Independence, MO 64057
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Retail Space For Lease/Sale
Contact for pricing
3,908 SF

Retail Space For Lease/Sale

Retail spaces and pad sites available for lease or sale.

4600 S Noland Rd, Independence, MO 64055
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Retail Space in High-Traffic Area
Contact for pricing
8,000 SF

Retail Space in High-Traffic Area

Retail spaces available in a 300,000 SF shopping center.

13500-13920 E Us Highway 40, Independence, MO 64055
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Retail Space Near Grocery Store
Contact for pricing
1,310 SF

Retail Space Near Grocery Store

Retail spaces available with high visibility and traffic counts.

4540 S Noland Rd, Independence, MO 64055
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Freestanding Retail Building For Lease
Contact for pricing
5,653 SF

Freestanding Retail Building For Lease

5,653 SF freestanding retail building in established Independence, Missouri corridor.

19921 E Jackson Dr, Independence, MO 64057
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Retail Space Near Highway 291
Contact for pricing
2,000 SF

Retail Space Near Highway 291

Retail space available near major retailers and medical center.

19130 E 39Th St S D, Independence, MO 64057
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Office Space with Private Restroom
Contact for pricing
1,361 SF

Office Space with Private Restroom

Office space featuring private offices, restroom, and designated storage.

14405 E 42Nd St S, Independence, MO 64055
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Retail Space in Major Corridor
Contact for pricing
3,200 SF

Retail Space in Major Corridor

3,200 SF retail space in high-traffic Independence location.

3503-3545 S Noland Rd, Independence, MO 64050
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Retail Space Near Highway 291
Contact for pricing
2,228 SF

Retail Space Near Highway 291

Retail space available near major retailers and high-traffic areas.

18800-19120 E 39Th St S, Independence, MO 64057
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Retail Space in Independence Center
Contact for pricing
779 SF

Retail Space in Independence Center

Retail spaces available for lease in a super-regional shopping mall.

18801-18813 E 39Th St S, Independence, MO 64057
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Office Spaces Available in 2025
Contact for pricing
1,237 SF

Office Spaces Available in 2025

Office spaces for rent with ample parking and updates.

3675 S Noland Rd, Independence, MO 64055
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Medical Office Space For Rent
Contact for pricing
5,276 SF

Medical Office Space For Rent

Medical office space with hospital access and ample parking.

19550-19600 E 39Th St S, Independence, MO 64057
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Retail Space in Upgraded Center
Contact for pricing
3,900 SF

Retail Space in Upgraded Center

Retail spaces available in recently upgraded shopping center.

17911-18011 E Us Highway 24, Independence, MO 64056
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Renovated Office Space Available
Contact for pricing
7,575 SF

Renovated Office Space Available

3,000-7,575 SF office space for lease after 2021 renovations.

201 E Partridge Ave, Independence, MO 64055
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Independence, MO Commercial real estate Leasing Opportunities Market Analysis

Explore Commercial real estate leasing options in Independence, MO with 140 listings featured on our commercial real estate exchange. The current inventory includes 22,745,437,721 square feet of properties with an estimated lease value of $379 /Mo.

Estimated lease rates for Commercial real estate in Independence, MO begin at $10 SF/Yr, with an average of $34 SF/Yr and extend to $228 SF/Yr.
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