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    Mechanicsburg, PA Commercial Real Estate for Lease

    82 results
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    Mechanicsburg Retail and Office Spaces
    $550 / Mo
    164,657 SF

    Mechanicsburg Retail and Office Spaces

    5275 E Trindle Rd, Mechanicsburg, PA 17050

    Renovated retail and office spaces with ample parking available for lease.

    • Brand new renovations to both retail storefronts and office spaces.
    • Ample parking available.
    • Excellent connectivity to Rt. 83, I‑81, and East/West Shores.
    • First floor retail/office spaces available from 1,500SF up to 6,500SF with drive‑thru potential.
    • Second floor turn‑key furnished private executive offices starting at $550/month.
    Updated: Jan 5
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    Office Space in Mechanicsburg, PA
    $12,000 / Mo
    40,075 SF

    Office Space in Mechanicsburg, PA

    Cumberland Pkwy, Mechanicsburg, PA 17055

    Professional office space available for lease in Mechanicsburg, PA.

    • Up to 5,000 SF available.
    • Great location and visibility.
    • Zoned Professional Office.
    • Build to suit.
    • Central Air cooling.
    Updated: Dec 22, 2025
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    Mechanicsburg Retail Space For Lease
    $1,500 / Mo
    17,860 SF

    Mechanicsburg Retail Space For Lease

    Retail space available for lease in Mechanicsburg, Pennsylvania.

    2-8 W Allen St, Mechanicsburg, PA 17055
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    Carlisle Pike Retail/Office Space
    $995 / Mo
    36,000 SF

    Carlisle Pike Retail/Office Space

    Highly visible space on Carlisle Pike, suitable for office/retail.

    5515-5521 Carlisle Pike, Mechanicsburg, PA 17050
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    Refurbished Office Suites on Trindle
    $18 SF/Yr
    510 SF

    Refurbished Office Suites on Trindle

    Versatile office spaces with monument signage and ample parking.

    5021-5023 E Trindle Rd, Mechanicsburg, PA 17050
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    Mechanicsburg Medical Office Suite
    $19 SF/Yr
    4,250 SF

    Mechanicsburg Medical Office Suite

    Class A medical office suite in Mechanicsburg's Waterford Building.

    21 Waterford Dr, Mechanicsburg, PA 17050
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    Carlisle Pike Retail/Office Space
    $995 / Mo
    800 SF

    Carlisle Pike Retail/Office Space

    Highly visible retail or office spaces on Carlisle Pike.

    5521 Carlisle Pike, Mechanicsburg, PA 17050
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    Mechanicsburg Office/Flex Suites Available
    $9 SF/Yr
    79,193 SF

    Mechanicsburg Office/Flex Suites Available

    Adaptable office and flex suites in well-maintained Mechanicsburg business park.

    5095 Ritter Rd, Mechanicsburg, PA 17055
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    Mechanicsburg Office Space For Rent
    $14 SF/Yr
    8,700 SF

    Mechanicsburg Office Space For Rent

    Office space in Mechanicsburg with private offices, reception, and kitchenette.

    5 Kacey Ct, Mechanicsburg, PA 17055
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    Mechanicsburg Corner Office Suite
    $17 SF/Yr
    9,820 SF

    Mechanicsburg Corner Office Suite

    Two-story office building with renovated 1,540 SF corner suite.

    2 Kacey Ct, Mechanicsburg, PA 17055
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    Class A Office Suite Available
    $17 SF/Yr
    48,000 SF

    Class A Office Suite Available

    7,088 SF Class A office space with solar power.

    4550 Lena Dr, Mechanicsburg, PA 17055
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    Mechanicsburg Flex Space with Garage
    $12,750 / Mo

    Mechanicsburg Flex Space with Garage

    Flex space featuring a workroom, offices, restroom, and garage.

    5020 Ritter Rd, Mechanicsburg, PA 17055
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    Modern Office Space Available
    $12 SF/Yr
    2,000 SF

    Modern Office Space Available

    Professional office space with flexible floor plans and modern amenities.

    5010 Ritter Rd, Mechanicsburg, PA 17055
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    Mechanicsburg Office Space For Rent
    $16 SF/Yr
    1,000 SF

    Mechanicsburg Office Space For Rent

    Office space available for lease in Mechanicsburg, Pennsylvania.

    2 Market Plaza Way, Mechanicsburg, PA 17055
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    Retail Space on Carlisle Pike
    $21 SF/Yr
    9,200 SF

    Retail Space on Carlisle Pike

    Retail space available with high visibility and traffic.

    4713 Carlisle Pike, Mechanicsburg, PA 17050
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    Mechanicsburg Warehouse Space Available
    $9 SF/Yr
    49,311 SF

    Mechanicsburg Warehouse Space Available

    Customizable warehouse space with convenient highway access.

    381 Independence Ave, Mechanicsburg, PA 17055
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    Prestigious Office Space in Mechanicsburg
    $21 SF/Yr
    56,107 SF

    Prestigious Office Space in Mechanicsburg

    Office space available in Bent Creek Business Park.

    1700 Bent Creek Blvd, Mechanicsburg, PA 17050
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    Mechanicsburg Office Space Available
    $18 SF/Yr
    38,000 SF

    Mechanicsburg Office Space Available

    First-class office space for lease in Mechanicsburg, Pennsylvania.

    1000 Bent Creek Blvd, Mechanicsburg, PA 17050
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    Commercial Land For Lease
    $25 SF/Yr
    3,200 SF

    Commercial Land For Lease

    Commercial land available for lease with potential for retail uses.

    4618 Carlisle Pike, Mechanicsburg, PA 17050
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    Mechanicsburg Industrial Warehouse Space
    $5 SF/Yr
    32,730 SF

    Mechanicsburg Industrial Warehouse Space

    Versatile industrial warehouse space in Silver Spring Township available for lease.

    2 Brenneman Cir, Mechanicsburg, PA 17050
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    Established Corner Restaurant Opportunity
    Contact for pricing
    1,100 SF

    Established Corner Restaurant Opportunity

    Corner retail/restaurant location available for lease.

    5155 Simpson Ferry Rd, Mechanicsburg, PA 17050
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    Land Ready for Build-to-Suit
    Contact for pricing
    3 SF

    Land Ready for Build-to-Suit

    3-acre land suitable for up to 18,000 SF building.

    5041 Louise Dr, Mechanicsburg, PA 17055
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    Mechanicsburg Build-to-Suit Land For Rent
    Contact for pricing

    Mechanicsburg Build-to-Suit Land For Rent

    Land suitable for flex building with permitted uses.

    5041 Richard Ln, Mechanicsburg, PA 17055
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    Mechanicsburg Industrial Space For Lease
    Contact for pricing
    342,500 SF

    Mechanicsburg Industrial Space For Lease

    342,500 SF industrial space in premier logistics corridor.

    500 Independence Ave, Mechanicsburg, PA 17055
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    Mechanicsburg, PA Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Mechanicsburg, PA with 130 listings featured on our commercial real estate exchange. The current inventory includes 56,525,712,357 square feet of properties with an estimated lease value of $617 /Mo.

    Estimated lease rates for Commercial real estate in Mechanicsburg, PA begin at $1.01 SF/Yr, with an average of $16 SF/Yr and extend to $55 SF/Yr.
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