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Lowell, MA Commercial Real Estate for Lease

37 results
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Downtown Lowell Retail Space Available
$2,000 / Mo
5,227 SF

Downtown Lowell Retail Space Available

183 Appleton St, Lowell, MA 01852

600 SF retail space in a high-traffic downtown location.

  • Highly visible, well‑traveled downtown location
  • Off‑street parking for customers and staff
  • 600 sq ft standalone retail space
  • Private office area
  • Employee bathroom
Updated: Dec 12, 2025
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Retail Space in High-Traffic Plaza
$22 SF/Yr

Retail Space in High-Traffic Plaza

1270 Westford St, Lowell, MA 01851

Retail space in a vibrant, high-traffic location near Route 3.

  • Strategic location on the Drum Hill retail corridor near Route 3 and the Lowell line.
  • High visibility and convenient access.
  • Abundant parking.
  • Anchored by a dynamic mix of national and regional retailers.
  • Strong demographics and heavy daily traffic counts.
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Second Floor Corner Office Unit
$950 / Mo

Second Floor Corner Office Unit

Second floor office unit available for rent in Methuen.

12 Baldwin St, Lowell, MA 01851
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Retail Space on Mammoth Road
$1,000 / Mo
1,200 SF

Retail Space on Mammoth Road

Retail space for lease on heavily traveled Mammoth Road.

49-51 Mammoth Rd, Lowell, MA 01854
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Downtown Lowell Equipped Bar Space
$2,500 / Mo

Downtown Lowell Equipped Bar Space

Equipped bar space for lease in downtown Lowell.

15-2 Kearney Sq, Lowell, MA 01852
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Automotive Repair Garage For Lease
Contact for pricing
658 SF

Automotive Repair Garage For Lease

Freestanding automotive repair garage available for lease in Lowell, MA.

397 School St, Lowell, MA 01851
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Retail Space Available on Route 3A
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Retail Space Available on Route 3A

Retail spaces available with high traffic and signalized access.

199- Plain St, Lowell, MA 01852
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Renovated Retail/Office Suite in Lowell
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1,087 SF

Renovated Retail/Office Suite in Lowell

Newly renovated retail/office suite available for lease in Downtown Lowell.

134-142 Middlesex St, Lowell, MA 01852
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Retail Space on Route 3A
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2,600 SF

Retail Space on Route 3A

Retail spaces available with high traffic and signalized access.

199 Plain St, Lowell, MA 01852
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Retail Space in Central Plaza
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3,500 SF

Retail Space in Central Plaza

Retail space available in a busy central business district.

55-131 Church St, Lowell, MA 01852
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Downtown Lowell Office/Retail Suite
$12 SF/Yr

Downtown Lowell Office/Retail Suite

Spacious 3,000 sq. ft. office/retail suite in downtown Lowell.

50 Central St, Lowell, MA 01852
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Class A Office Space Lowell
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97,686 SF

Class A Office Space Lowell

Prestigious office park with modern amenities, convenient suburban location.

59 Lowes Way, Lowell, MA 01851
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Downtown Lowell Office Space Available
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33,000 SF

Downtown Lowell Office Space Available

Office space for lease in historic downtown Lowell.

81 Bridge St, Lowell, MA 01852
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Retail Space in Lowell, MA
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Retail Space in Lowell, MA

Prominent retail property in a bustling commercial district.

181-211 Plain St, Lowell, MA 01852
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Lowell Flex / Lab Space
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28,500 SF

Lowell Flex / Lab Space

Flex / lab space available in Lowell, Massachusetts.

10 Technology Dr, Lowell, MA 01851
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Versatile Office Space Available
Contact for pricing
5,741 SF

Versatile Office Space Available

Adaptable office space with modern amenities and ample parking.

34 Wellman St, Lowell, MA 01851
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Office/Light Manufacturing/Warehouse Facility For Rent
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43,908 SF

Office/Light Manufacturing/Warehouse Facility For Rent

Three-story office/light manufacturing/warehouse facility near I-495 and Route 3.

1001 Pawtucket Blvd, Lowell, MA 01854
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Expansive Retail Space Available
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6,500 SF

Expansive Retail Space Available

6500 Sq Ft first floor retail unit for rent.

1088-1100 Gorham St, Lowell, MA 01852
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New Retail and Office Opportunity
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New Retail and Office Opportunity

New retail and office spaces available in Lowell, MA.

408 Suffolk St, Lowell, MA 01854
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Downtown Lowell Restaurant For Lease
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Downtown Lowell Restaurant For Lease

Established restaurant space available for lease in downtown Lowell.

15 Kearney Sq, Lowell, MA 01852
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Updated Retail/Office Space Available
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Updated Retail/Office Space Available

Retail or office space with recent updates and high traffic.

200 University Ave, Lowell, MA 01854
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Historic Building Retail Space Available
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Historic Building Retail Space Available

Commercial space in historic building with flexible uses for rent.

635 Middlesex St, Lowell, MA 01851
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Updated Retail Space Available
Contact for pricing
1,680 SF

Updated Retail Space Available

Renovated retail space with high traffic near UMass campus.

198 University Ave, Lowell, MA 01854
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Renovated Office Space in Lowell
Contact for pricing
29,607 SF

Renovated Office Space in Lowell

Historic mill with modern amenities and high-tech capabilities.

650 Suffolk St, Lowell, MA 01854
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Lowell, MA Commercial real estate Leasing Opportunities Market Analysis

Explore Commercial real estate leasing options in Lowell, MA with 70 listings featured on our commercial real estate exchange. The current inventory includes 5,162,347,881 square feet of properties with an estimated lease value of $66 SF/Yr.

Estimated lease rates for Commercial real estate in Lowell, MA begin at $4 SF/Yr, with an average of $13 SF/Yr and extend to $23 SF/Yr.
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