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    Key Largo, FL Commercial Real Estate for Sale

    99 results
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    Turnkey Inn & Hospitality Investment
    $14,900,000
    23,092 SF

    Turnkey Inn & Hospitality Investment

    99202 Overseas Hwy, Key Largo, FL 33037

    Income-producing inn with development potential in prime Key Largo location.

    • Turnkey, income‑producing inn in a prime Key Largo location.
    • Includes 50 transferable transient licenses (nightly rentals) offering exceptional short‑term rental income.
    • Features a 5COP full liquor license for the on‑site restaurant and bar.
    • 50 total guest rooms, including 12 spacious two‑room suites.
    • Highly visible location with 450 feet on US 1 and 9 parcels included.
    Updated: Jan 27
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    Key Largo Vacant RV Lot
    $300,000

    Key Largo Vacant RV Lot

    101551 Overseas Hwy, Key Largo, FL 33037

    Vacant RV lot in Key Largo Kampground & Marina.

    • Income‑producing potential with existing rental program earning approximately $125-$150 per night.
    • Prime location in Key Largo Kampground & Marina, a premier RV/campground and marina community in the Florida Keys.
    • Extensive amenity package including a heated swimming pool, marina, beaches, sports courts, playground, and clubhouse.
    • Located on 40 scenic oceanside acres inside of John Pennekamp State Park.
    • Full RV hookups (30/50 amp), gated security, and Wi‑Fi access.
    Updated: Feb 17
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    Key Largo Commercial Space Available
    Contact for pricing

    Key Largo Commercial Space Available

    5,457 sqft commercial space in Key Largo for lease.

    99451 Overseas Hwy, Key Largo, FL 33037
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    Waterfront Property for Rehab/Assisted Living
    $13,499,000
    1.77 Acres

    Waterfront Property for Rehab/Assisted Living

    Waterfront property ideal for rehab center or assisted living facility.

    97340-60 Overseas Hwy, Key Largo, FL 33037
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    Iconic Waterfront Restaurant and Bar
    $4,900,000

    Iconic Waterfront Restaurant and Bar

    Legendary waterfront restaurant/bar with long-term lease in Key Largo, FL.

    58000 Card Sound Rd, Key Largo, FL 33037
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    Key Largo Restaurant with Drive-Through
    $2,199,000

    Key Largo Restaurant with Drive-Through

    Profitable franchise with real estate and drive-through in Key Largo.

    92661 Overseas Hwy, Key Largo, FL 33037
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    Highway Frontage Commercial Building
    Contact for pricing

    Highway Frontage Commercial Building

    Commercial building with highway frontage and upstairs space for lease.

    106600 Overseas Hwy, Key Largo, FL 33037
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    Unfinished Retail Space Opportunity
    Contact for pricing

    Unfinished Retail Space Opportunity

    Second floor unfinished retail space available for sale.

    106600 Overseas Hwy, Key Largo, FL 33037
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    Highway Frontage Commercial Building
    Contact for pricing

    Highway Frontage Commercial Building

    Commercial building with highway frontage and additional rental options.

    106600 Overseas Hwy, Key Largo, FL 33037
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    Vacant Land in Key Largo
    $95,000

    Vacant Land in Key Largo

    Vacant lot in Key Largo, perfect for building or investment.

    109 Jasmine Dr, Key Largo, FL 33037
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    Mixed-Use Commercial Building For Sale
    $2,995,000

    Mixed-Use Commercial Building For Sale

    Mixed-use commercial building with US 1 visibility in Tavernier.

    92295 Old State Rd, Key Largo, FL 33070
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    Commercial Building Lot Opportunity
    $1,295,000

    Commercial Building Lot Opportunity

    Approved site plan for a 2,500 sq. ft. commercial building.

    101201 Overseas Hwy, Key Largo, FL 33037
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    Key Largo Commercial Real Estate Opportunity
    $2,995,000

    Key Largo Commercial Real Estate Opportunity

    Commercial property with dual exposure in Key Largo, Florida.

    98250 Overseas Hwy, Key Largo, FL 33037
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    Key Largo Retail Investment Opportunity
    $2,990,000

    Key Largo Retail Investment Opportunity

    2,400 SF building with vacant lot in Key Largo.

    102970 Overseas Hwy, Key Largo, FL 33037
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    Commercial Vacant Land Key Largo
    $169,000

    Commercial Vacant Land Key Largo

    Commercial vacant lot with high visibility and easy access.

    106360 Overseas Hwy, Key Largo, FL 33037
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    Key Largo Oceanside Commercial Building
    $5,400,000

    Key Largo Oceanside Commercial Building

    Commercial building with deep water dockage and direct ocean access.

    522 Caribbean Dr, Key Largo, FL 33037
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    Key Largo Lot with RV
    $325,000
    0.03 Acres

    Key Largo Lot with RV

    Lot with RV, utilities, and community amenities in Key Largo.

    325 Calusa St, Key Largo, FL 33037
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    Key Largo Mixed-Use Property
    $1,790,000

    Key Largo Mixed-Use Property

    High-visibility mixed-use property with commercial storefront and residential apartment.

    100636 Overseas Hwy, Key Largo, FL 33037
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    Key Largo Retail Investment Opportunity
    $2,965,000
    0.46 Acres

    Key Largo Retail Investment Opportunity

    2,400 SF building with adjacent lot in Key Largo.

    102970 Overseas Hwy, Key Largo, FL 33037
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    Buildable Vacant Land in Key Largo
    $220,000

    Buildable Vacant Land in Key Largo

    Value-priced, fully buildable lot near Key Largo Elementary School.

    10 N Marlin Ave, Key Largo, FL 33037
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    Oceanside Marina in Florida Keys
    $5,000,000

    Oceanside Marina in Florida Keys

    Marina with deep-water dockage, RV pads, and investment potential.

    199 Morris Ave, Key Largo, FL 33037
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    Key Largo Storage and Marina
    Contact for pricing

    Key Largo Storage and Marina

    Storage and marina with dockage in Key Largo, Florida.

    106600 Overseas Hwy, Key Largo, FL 33037
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    Private Island with Marina
    Contact for pricing
    26.00 Acres

    Private Island with Marina

    26-acre private island with marina and mainland home.

    10 Cannon Pt, Key Largo, FL 33037
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    Overseas Highway Commercial Property
    $2,850,000

    Overseas Highway Commercial Property

    Road frontage property with storage yard and marina license.

    98468 Overseas Hwy, Key Largo, FL 33037
    View details

    Key Largo, FL Commercial Real Estate Investment Opportunities Market Analysis

    Explore 38 commercial real estate for sale in Key Largo, FL, showcased through 99 active listings on our real estate platform. These investment opportunities span a total of 1,324,507 square feet of properties for sale, with an estimated market value of $110,689,000.

    Sale prices for business properties in Key Largo, FL start at $325,000, averaging $18,448,166, and reaching up to $75,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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