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    West Columbia, SC Commercial Real Estate for Lease

    61 results
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    Versatile Commercial Space in West Columbia
    $4,800 / Mo
    23,087 SF

    Versatile Commercial Space in West Columbia

    818 Williams St, West Columbia, SC 29169

    Functional warehouse and office space with mezzanine, ideal for various uses.

    • Over 10,000 SF of functional space at an exceptional value.
    • LM zoning allows for a wide range of uses.
    • Versatile property combining warehouse functionality with finished office space.
    • Upstairs mezzanine (1,064 SF) framed and wired, ready to be finished.
    • Two sliding bay doors (15' wide and 13' high) and 14' clear ceiling height in the warehouse.
    Updated: Dec 22, 2025
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    Medical Office Space For Lease
    $20 SF/Yr
    7,659 SF

    Medical Office Space For Lease

    161 Medical Cir, West Columbia, SC 29169

    Medical office space in prime healthcare corridor location.

    • Located across Sunset Blvd. from Lexington Medical Center
    • Prime healthcare corridor location
    • Exam rooms with plumbing
    • 3,155 SF medical office space for lease
    • Excellent visibility & signage opportunities
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    Class-A Mixed-Use Development For Rent
    Contact for pricing
    15,000 SF

    Class-A Mixed-Use Development For Rent

    New mixed-use development with commercial and residential spaces available for rent.

    351 Meeting St, West Columbia, SC 29169
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    Office Suite in West Columbia
    $15 SF/Yr
    9,890 SF

    Office Suite in West Columbia

    Office suite for lease near downtown Columbia and Lexington Medical Center.

    1523 Sunset Blvd, West Columbia, SC 29169
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    West Columbia Office/Medical Suite
    $18 SF/Yr
    12,000 SF

    West Columbia Office/Medical Suite

    Office/medical suite for lease near Lexington Medical Hospital.

    3618 Sunset Blvd, West Columbia, SC 29169
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    West Columbia Showroom/Office/Flex Space
    $14 SF/Yr
    19,000 SF

    West Columbia Showroom/Office/Flex Space

    17,800 SF showroom/office/flex space available for sublease in West Columbia.

    100 Corporate Blvd, West Columbia, SC 29169
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    West Columbia Office/Retail Space
    Contact for pricing
    15,000 SF

    West Columbia Office/Retail Space

    1,438 SF office/retail space in a vibrant community.

    121 State St, West Columbia, SC 29169
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    Freestanding Building in West Columbia
    $18 SF/Yr
    10,000 SF

    Freestanding Building in West Columbia

    10,125 SF freestanding building on a busy retail corridor.

    1210 Charleston Hwy, West Columbia, SC 29169
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    Highly Visible Office Space
    Contact for pricing
    7,838 SF

    Highly Visible Office Space

    Office space with ample parking near downtown and central business

    501 State St, West Columbia, SC 29169
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    West Columbia Office/Warehouse Space
    Contact for pricing
    4,662 SF

    West Columbia Office/Warehouse Space

    4,662 SF office and warehouse space for lease.

    1049 Sunset Blvd, West Columbia, SC 29169
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    West Columbia Freestanding Retail Building
    $18 SF/Yr
    10,125 SF

    West Columbia Freestanding Retail Building

    Freestanding retail building in West Columbia available for lease/sale.

    1210 Charleston Hwy, West Columbia, SC
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    Flex Space Near Interstate Access
    $15 SF/Yr
    2,305 SF

    Flex Space Near Interstate Access

    Flex space in professional park with easy interstate access.

    104 Corporate Blvd, West Columbia, SC 29169
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    Medical Office Space Available
    Contact for pricing
    39,722 SF

    Medical Office Space Available

    Accessible medical office space in a growing Columbia corridor.

    3221 Sunset Blvd, West Columbia, SC 29169
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    West Columbia Office Space Available
    $19 SF/Yr
    7,200 SF

    West Columbia Office Space Available

    Office space for lease near Lexington Medical Center corridor.

    3634 Sunset Blvd, West Columbia, SC 29169
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    West Columbia Warehouse with Loading
    $8 SF/Yr
    30,000 SF

    West Columbia Warehouse with Loading

    30,000 SF office/warehouse with loading docks and drive-in bay.

    120 Queen Pkwy, West Columbia, SC 29169
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    West Columbia Retail/Office Space
    Contact for pricing
    1,343 SF

    West Columbia Retail/Office Space

    Retail/office suite available in West Columbia with high visibility.

    501-521 Meeting St, West Columbia, SC 29169
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    West Columbia Retail/Restaurant Space
    Contact for pricing
    2,200 SF

    West Columbia Retail/Restaurant Space

    Retail or restaurant space with ample parking and high traffic.

    1471 Platt Spg Rd, West Columbia, SC
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    Medical Office Near Lexington Medical
    Contact for pricing
    1,711 SF

    Medical Office Near Lexington Medical

    Medical office building for lease near Lexington Medical Center.

    3119 Sunset Blvd, West Columbia, SC 29169
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    Retail Space on Airport Boulevard
    Contact for pricing
    17,633 SF

    Retail Space on Airport Boulevard

    17,633 SF retail space for lease with on-site parking.

    1640 Airport Blvd, West Columbia, SC
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    Retail Space in City Market
    Contact for pricing
    7,596 SF

    Retail Space in City Market

    Retail space available in the Triangle City Market Area.

    612-622 12 St, West Columbia, SC
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    Professional Office Space Available
    Contact for pricing
    1,300 SF

    Professional Office Space Available

    1,300 SF office space with private offices and reception.

    1087 Harbor Dr, West Columbia, SC 29169
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    Retail Space Near Lexington Medical
    Contact for pricing
    2,500 SF

    Retail Space Near Lexington Medical

    Retail space available near Lexington Medical Center and Downtown Columbia.

    1811 Sunset Blvd, West Columbia, SC 29169
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    Class A Office Space Available
    Contact for pricing
    9,400 SF

    Class A Office Space Available

    Well-maintained Class A office space with modern amenities for lease.

    110 Saxe Gotha Rd, West Columbia, SC
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    West Columbia Flex/Industrial/Office Space
    Contact for pricing
    6,500 SF

    West Columbia Flex/Industrial/Office Space

    Meticulously maintained flex/industrial/office space in West Columbia for lease.

    2 C Trotter Rd, West Columbia, SC 29169
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    West Columbia, SC Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in West Columbia, SC with 135 listings featured on our commercial real estate exchange. The current inventory includes 29,365,268,362 square feet of properties with an estimated lease value of $239 SF/Yr.

    Estimated lease rates for Commercial real estate in West Columbia, SC begin at $2 SF/Yr, with an average of $13 SF/Yr and extend to $20 SF/Yr.
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