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    Panama City, FL Commercial Real Estate for Lease

    183 results
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    Downtown Panama City Office Space
    $21 SF/Yr
    1,906 SF

    Downtown Panama City Office Space

    455 Harrison Ave, Panama City, FL 32401

    Professional office space in downtown Panama City for lease.

    • Prime Downtown Panama City location on Harrison Avenue.
    • 1906 sq ft of professional office space.
    • Well‑maintained: Rebuilt in the early 2000s and consistently occupied since.
    • Includes a large executive office, two senior level offices, three staff offices, and a conference room.
    • Features two accessible bathrooms and a breakroom.
    Updated: Feb 12
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    Versatile Commercial Building on Highway 77
    $5,000 / Mo
    4,814 SF

    Versatile Commercial Building on Highway 77

    13919 Highway 77, Panama City, FL 32409

    4,800 SF steel building on 1.24 acres with frontage.

    • High‑visibility location on rapidly growing Hwy 77.
    • 4,800 SF steel building on 1.24 acres with ample parking and easy trailer access.
    • Equipped with commercial‑grade septic system for a restaurant, existing kitchen hood range, and drive‑through setup.
    • Dedicated ingress/egress right on State Hwy 77.
    • Located near a 140‑home community under construction.
    Updated: Feb 18
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    Panama City Beach Commercial Property
    $7,250 / Mo
    2,418 SF

    Panama City Beach Commercial Property

    Commercial property in high-traffic area, previously a residential treatment center.

    9719 Thomas Dr, Panama City, FL 32408
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    Retail Space in Panama City
    $24 SF/Yr
    51,876 SF

    Retail Space in Panama City

    Retail space available for lease in Panama City, Florida.

    133 S Tyndall Pkwy, Panama City, FL 32404
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    Retail Center in Panama City
    $12 SF/Yr
    51,876 SF

    Retail Center in Panama City

    52,000 SF retail center, opening Spring 2027.

    133 S Tyndall Pkwy, Panama City, FL 32404
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    Retail Space in Panama City
    $24 SF/Yr
    51,876 SF

    Retail Space in Panama City

    Retail space available for lease in Panama City, Florida.

    133 S Tyndall Pkwy, Panama City, FL 32404
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    Retail Center in Panama City
    $22 SF/Yr
    51,896 SF

    Retail Center in Panama City

    Retail spaces available in Panama City, FL, opening Spring 2027.

    133 S Tyndall Pkwy, Panama City, FL 32404
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    Retail Center in Panama City
    $21 SF/Yr
    51,876 SF

    Retail Center in Panama City

    Retail spaces available in upcoming Panama City shopping center.

    133 S Tyndall Pkwy, Panama City, FL 32404
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    Retail Center in Panama City
    $16 SF/Yr
    51,876 SF

    Retail Center in Panama City

    Retail space available in Panama City, Florida.

    133 S Tyndall Pkwy, Panama City, FL 32404
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    Panama City Office Space Available
    $2,500 / Mo
    1,903 SF

    Panama City Office Space Available

    Well-located office building ideal for small businesses or professional services.

    309 E 7Th St, Panama City, FL 32401
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    Versatile Commercial Space Off Highway
    $3,500 / Mo
    6,500 SF

    Versatile Commercial Space Off Highway

    Flexible leasing options near Highway 231, ideal for various businesses.

    6804 Bayou George Dr, Panama City, FL 32404
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    Cleared Commercial Land For Lease
    $3,700 / Mo
    121,968 SF

    Cleared Commercial Land For Lease

    2.8 acres of vacant commercial land available for lease.

    2110 Industrial Dr, Panama City, FL 32405
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    Retail Space in Panama City
    $15 SF/Yr
    17,577 SF

    Retail Space in Panama City

    Open span retail space with office, breakroom, and bathrooms.

    401 E 23Rd St, Panama City, FL 32405
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    Versatile Office and Warehouse Space
    $5,000 / Mo

    Versatile Office and Warehouse Space

    Versatile office and warehouse space in an ideal location.

    1337 W 19Th St, Panama City, FL 32405
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    Office Space on 23rd Street
    $995 / Mo
    7,820 SF

    Office Space on 23rd Street

    Office space in a high-demand central location.

    330 W 23Rd St, Panama City, FL 32405
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    Downtown Panama City Warehouse Complex
    $8,500 / Mo
    8,464 SF

    Downtown Panama City Warehouse Complex

    Downtown Panama City warehouse complex with flexible leasing options.

    733 Mulberry Ave, Panama City, FL 32401
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    Warehouse with Office Space Available
    $3,000 / Mo
    6,130 SF

    Warehouse with Office Space Available

    Versatile commercial property with warehouse and office space for lease.

    2824 Highway 2321, Panama City, FL 32409
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    Retail Space on Highway 77
    $10,000 / Mo
    62,220 SF

    Retail Space on Highway 77

    Retail space in central location with storefront and roll door.

    3101 Highway 77, Panama City, FL 32405
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    Medical Office Space For Rent
    $18 SF/Yr
    2,801 SF

    Medical Office Space For Rent

    Well-designed medical office space with excellent visibility and convenient access.

    2420 Jenks Ave, Panama City, FL 32405
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    Professional Office Building For Rent
    $16 SF/Yr
    4,845 SF

    Professional Office Building For Rent

    Functional office space in Panama City's business district.

    833 Harrison Ave, Panama City, FL 32401
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    Downtown Panama City Commercial Space
    $15 SF/Yr
    2,700 SF

    Downtown Panama City Commercial Space

    Versatile commercial space in historic downtown Panama City with parking.

    416 Jenks Ave, Panama City, FL 32401
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    Highway 77 Commercial Opportunity
    $5,000 / Mo
    4,814 SF

    Highway 77 Commercial Opportunity

    Versatile 4,800 SF building on 1.24 acres for rent.

    13919 Highway 77, Panama City, FL 32409
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    Move-in Ready Medical Office Suite
    $20 SF/Yr
    2,604 SF

    Move-in Ready Medical Office Suite

    Fully built-out medical office with exam rooms and parking.

    2338 State Ave, Panama City, FL 32405
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    Downtown Office Space For Rent
    $2,850 / Mo
    4,309 SF

    Downtown Office Space For Rent

    Spacious downtown office with bayou views and convenient amenities.

    231 E Beach Dr, Panama City, FL 32401
    View details

    Panama City, FL Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Panama City, FL with 624 listings featured on our commercial real estate exchange. The current inventory includes 107,927,697,240 square feet of properties with an estimated lease value of $1,834 /Mo.

    Estimated lease rates for Commercial real estate in Panama City, FL begin at $0.55 SF/Yr, with an average of $17 SF/Yr and extend to $45 SF/Yr.
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