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    Des Moines, IA Commercial Real Estate for Sale

    369 results
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    Adaptable Commercial Space, Des Moines/Ankeny
    $950,000
    1.86 Acres

    Adaptable Commercial Space, Des Moines/Ankeny

    1380 NE 66Th Ave, Des Moines, IA 50313

    Renovated commercial space suitable for retail, office, or service businesses.

    • Extensively renovated in 2017 with modern finishes and updated systems.
    • Highly adaptable layout suitable for retail, office, studio, or service‑oriented businesses.
    • Prime location on NE 66th Avenue in the Des Moines/Ankeny corridor with convenient access and visibility.
    • Recent addition in 2024 enhances functionality and square footage.
    • Move‑in‑ready condition, ideal for immediate occupancy and operation.
    Updated: Jan 26
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    Des Moines Office/Warehouse Opportunity
    $425,000
    1.74 Acres

    Des Moines Office/Warehouse Opportunity

    2679 Maury St, Des Moines, IA 50317

    Over 5000 sq ft building suitable for office or warehouse.

    • Large Building: Over 5000 sq ft of usable space.
    • Ample Parking: 22,000 sq ft of exterior parking area.
    • Flexible Usage: Suitable for office or warehouse purposes.
    • High Ceilings: 12'6" ceiling height.
    • Durable Construction: Brick construction.
    Updated: Nov 29, 2025
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    Automotive Shop in Des Moines
    $325,000
    0.16 Acres

    Automotive Shop in Des Moines

    Fully functioning automotive shop in a high-traffic location.

    1501 6Th Ave, Des Moines, IA 50314
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    Historic Mixed-Use Property For Sale
    $225,000
    3,550 SF

    Historic Mixed-Use Property For Sale

    Unique mixed-use property with commercial space and residential apartments.

    3516 SW 9Th St, Des Moines, IA 50315
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    Des Moines Land Opportunity
    $300,000
    1.92 Acres

    Des Moines Land Opportunity

    1.92 acres of land suitable for development.

    3101 SE 22Nd St, Des Moines, IA 50320
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    Des Moines Duplex: Investment Opportunity
    $195,000
    1,282 SF

    Des Moines Duplex: Investment Opportunity

    Charming Des Moines duplex, ideal for investors or homeowners.

    1442 34Th St, Des Moines, IA 50311
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    Productive Farmland Near Des Moines
    Contact for pricing
    231.09 Acres

    Productive Farmland Near Des Moines

    231-acre farm with high CSR2 rating and highway access.

    Hartford Ave, Des Moines, IA 50320
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    Commercial Land Near Des Moines Airport
    $535,000
    1.42 Acres

    Commercial Land Near Des Moines Airport

    Commercial land near Des Moines Airport, ideal for entrepreneurs.

    2501 Mckinley Ave, Des Moines, IA 50321
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    Des Moines Retail Property For Sale
    $1,600,000
    1.09 Acres

    Des Moines Retail Property For Sale

    Retail property available for sale in Des Moines, Iowa.

    606 E Army Post Rd, Des Moines, IA 50315
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    Retail Center on E University
    $1,680,000
    0.76 Acres

    Retail Center on E University

    Fully leased retail center with high visibility on E University.

    2910 E University Ave, Des Moines, IA 50317
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    Des Moines Land Opportunity
    $149,950
    2.49 Acres

    Des Moines Land Opportunity

    2.49-acre parcel with potential for high-density residential conversion.

    2009-2013 Martin Luther King Jr Pkwy, Des Moines, IA 50314
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    Ocean-View Development Land in Ostional
    $1,900,000
    19.84 Acres

    Ocean-View Development Land in Ostional

    19.84-acre development land with ocean views, subdivided into 20 lots.

    Playa Ostional, Des Moines, IA 50309
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    Historic Office Condo For Sale
    $335,000
    2,028 SF

    Historic Office Condo For Sale

    Office condo in historic building near Court Avenue District.

    100 Court Ave, Des Moines, IA 50309
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    Des Moines Commercial Corridor Property
    $550,000

    Des Moines Commercial Corridor Property

    Well-maintained property in accessible commercial corridor, ideal for various businesses.

    3508 Delaware Ave, Des Moines, IA 50313
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    Luxury Villas Near Costa Rica Beach
    $799,000
    2,691 SF

    Luxury Villas Near Costa Rica Beach

    Boutique villas, walk to beach, income potential.

    Villas Cabuya, Des Moines, IA 50308
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    Versatile Des Moines Commercial Building
    $2,133,600

    Versatile Des Moines Commercial Building

    17,780 SF building with office, shop, and warehouse space.

    1536 E Army Post Rd, Des Moines, IA 50320
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    Des Moines Commercial Development Land
    $300,000

    Des Moines Commercial Development Land

    Commercial development land for sale in Des Moines, Iowa.

    1475 Hart Ave, Des Moines, IA 50320
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    Profitable ATV Tour Business
    $250,000

    Profitable ATV Tour Business

    Turnkey ATV tour business in Tamarindo, Costa Rica.

    Atv Business Opportunity, Des Moines, IA 50309
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    Freestanding Retail Building For Sale
    $750,000

    Freestanding Retail Building For Sale

    Freestanding retail building in a mixed-use neighborhood.

    4931 Douglas Ave, Des Moines, IA 50310
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    Des Moines, IA Commercial Real Estate Investment Opportunities Market Analysis

    Explore 208 commercial real estate for sale in Des Moines, IA, showcased through 369 active listings on our real estate platform. These investment opportunities span a total of 7,748,683 square feet of properties for sale, with an estimated market value of $46,759,798.

    Sale prices for business properties in Des Moines, IA start at $149,950, averaging $1,263,778, and reaching up to $4,950,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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