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    Des Moines, IA Commercial Real Estate for Lease

    172 results
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    Hub Tower
    Contact for pricing

    Hub Tower

    Workspaces, services and support to help you work better in Miami Airport

    699 Walnut St, Des Moines, IA 50309
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    IA, Des Moines - Grand Ave
    Contact for pricing

    IA, Des Moines - Grand Ave

    2323 Grand Ave, Des Moines, IA 50312

    Workspaces, services and support to help you work better in John Hancock Center

    • Be part of a vibrant coworking community with dedicated desk or hot desking options in thousands of idyllic locations across the globe
    • Grow in a modern workplace with the added advantage of a benefits program offering exclusive discounts and bespoke procurement support
    • Access Regus' network of workspaces and business lounges as often as you need and take advantage of their exclusive benefits
    • Impress clients, hold memorable workshops, and deliver a winning pitch in Regus' meeting spaces, fully equipped for gatherings of any size
    • Collaborate with like‑minded professionals and enjoy regular networking and community events with a Regus membership
    Updated: Feb 19
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    Modern Turn-Key Office Space
    Contact for pricing
    1,800 SF

    Modern Turn-Key Office Space

    323 E Walnut St, Des Moines, IA 50309

    Turn-key office space with ample parking near I-235.

    • Turn‑key, modern office space ready for your business.
    • Ample on‑site parking for employees and clients.
    • Located at a lighted intersection.
    • Close‑proximity to I‑235.
    • Access via East 6th Street.
    Updated: Sep 25, 2025
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    Class A+ Office Space
    Contact for pricing
    4,182 SF

    Class A+ Office Space

    Premier office location with river views and modern amenities.

    110 E Court Ave, Des Moines, IA 50309
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    Retail Space in East Village
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    2,381 SF

    Retail Space in East Village

    Retail space for lease in the heart of East Village.

    418 E Grand Ave, Des Moines, IA 50309
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    Des Moines Retail Space For Lease
    $20 SF/Yr
    139,000 SF

    Des Moines Retail Space For Lease

    Prime Ingersoll Ave location, 1,893 sq ft available.

    2301 Ingersoll Ave, Des Moines, IA 50312
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    Des Moines Office Space for Lease
    $12 SF/Yr
    11,920 SF

    Des Moines Office Space for Lease

    Prime Des Moines office, flexible suites available.

    2501 Grand Ave, Des Moines, IA 50312
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    I-35 Des Moines Flex Space
    $9 SF/Yr
    9,600 SF

    I-35 Des Moines Flex Space

    Des Moines industrial space for lease.

    5741 22Nd St, Des Moines, IA 50313
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    Des Moines Class A Coworking Space
    $8 SF/Yr
    165,584 SF

    Des Moines Class A Coworking Space

    Downtown Des Moines: 26 Suites Available

    400 Locust St, Des Moines, IA 50309
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    Des Moines Industrial/Office Space
    Contact for pricing
    155,650 SF

    Des Moines Industrial/Office Space

    Prime Des Moines location, flexible space available.

    1901 Bell Ave, Des Moines, IA 50315
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    RiverPoint Flex Space: Des Moines
    $6 SF/Yr
    53,600 SF

    RiverPoint Flex Space: Des Moines

    Des Moines flex space; 7,204 SF available.

    600 7Th St, Des Moines, IA 50309
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    Des Moines Warehouse Space Available
    $4 SF/Yr
    130,078 SF

    Des Moines Warehouse Space Available

    130,078 SF Warehouse, Des Moines, IA

    2425 Hubbell Ave, Des Moines, IA 50317
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    Argonne Retail: Des Moines Gem
    $14 SF/Yr
    4,110 SF

    Argonne Retail: Des Moines Gem

    Prime Des Moines retail space, fully vacant.

    1723 Grand Ave, Des Moines, IA 50309
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    Court Avenue Office Space
    $20 SF/Yr
    92,296 SF

    Court Avenue Office Space

    Des Moines CBD, IA: Classic office space available.

    100 Court Ave, Des Moines, IA 50309
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    Des Moines Restaurant/Office Space
    $18 SF/Yr
    2,296 SF

    Des Moines Restaurant/Office Space

    Prime Des Moines location, 2,296 sq ft available.

    11th & Martin Luther King Jr Pkwy, Des Moines, IA 50309
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    Des Moines Retail Space: Prime Location
    $24 SF/Yr
    2,310 SF

    Des Moines Retail Space: Prime Location

    2,310 SF Retail Space, Des Moines, IA

    300 Martin Luther King Jr Pkwy, Des Moines, IA 50309
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    Des Moines Executive Office Suites
    $16 SF/Yr
    8,593 SF

    Des Moines Executive Office Suites

    Prestigious Des Moines Office Space Available

    130 3Rd St, Des Moines, IA 50309
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    Des Moines Executive Office Space
    Contact for pricing
    10,816 SF

    Des Moines Executive Office Space

    10,816 SF Office, Ample Parking

    2620 Fleur Dr, Des Moines, IA 50321
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    Des Moines Warehouse: 20,000 SF
    Contact for pricing
    20,000 SF

    Des Moines Warehouse: 20,000 SF

    Prime Des Moines warehouse, 20,000 sq ft, ample parking.

    113 8Th St, Des Moines, IA 50309
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    Des Moines Executive Office Space
    $16 SF/Yr
    18,378 SF

    Des Moines Executive Office Space

    Prime Des Moines Office, 2,576 sq ft Available

    420 Watson Powell Jr Way, Des Moines, IA 50309
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    699 Walnut St
    $8 SF/Yr
    15,518 SF

    699 Walnut St

    Office space • 15,518 SF

    699 Walnut St, Des Moines, IA 50309
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    Des Moines Medical Office Space
    $12 SF/Yr
    18,190 SF

    Des Moines Medical Office Space

    Prime Des Moines location, 6,401 SF vacant.

    1300 Walnut St, Des Moines, IA 50319
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    East Pointe Plaza: Des Moines Office
    $9 SF/Yr
    4,790 SF

    East Pointe Plaza: Des Moines Office

    Des Moines executive office suites available.

    2574 Hubbell Ave, Des Moines, IA 50317
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    Des Moines Flex Space Available
    $6 SF/Yr
    77,270 SF

    Des Moines Flex Space Available

    77,270 SF Flex Space, 8,160 SF Vacant

    1710 Guthrie Ave, Des Moines, IA 50316
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    Des Moines, IA Commercial Real Estate Leasing Opportunities Market Analysis

    Explore Commercial Real Estate leasing options in Des Moines, IA with 275 listings featured on our commercial real estate exchange. The current inventory includes 180,239,997,960 square feet of properties with an estimated lease value of $1,789 /Mo.

    Estimated lease rates for Commercial Real Estate in Des Moines, IA begin at $1.50 SF/Yr, with an average of $14 SF/Yr and extend to $34 SF/Yr.

    In Des Moines, IA, current lease rates show:

    • Office Properties & Spaces positioned at $14
    • Retail properties measuring $16
    • Retail space assessed at $17
    • Industrial properties calculated at $8
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    Browse Commercial real estate for Lease Near Des Moines, IA

    Popular Searches in Des Moines, IA

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    Most Searched ZIP Codes in Des Moines, IA

    • 50309
    • 50313
    • 50312
    • 50317
    • 50314
    • 50320
    • 50321
    • 50315
    • 50310
    • 50316
    • 50311
    • 50322

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