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Des Moines, IA Commercial Real Estate for Lease

204 results
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Hub Tower
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Hub Tower

Workspaces, services and support to help you work better in Miami Airport

699 Walnut St, Des Moines, IA 50309
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IA, Des Moines - Grand Ave
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IA, Des Moines - Grand Ave

2323 Grand Ave, Des Moines, IA 50312

Workspaces, services and support to help you work better in John Hancock Center

  • Be part of a vibrant coworking community with dedicated desk or hot desking options in thousands of idyllic locations across the globe
  • Grow in a modern workplace with the added advantage of a benefits program offering exclusive discounts and bespoke procurement support
  • Access Regus' network of workspaces and business lounges as often as you need and take advantage of their exclusive benefits
  • Impress clients, hold memorable workshops, and deliver a winning pitch in Regus' meeting spaces, fully equipped for gatherings of any size
  • Collaborate with like‑minded professionals and enjoy regular networking and community events with a Regus membership
Updated: Feb 19
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Retail Space on SE 14th
$15 SF/Yr
1,400 SF

Retail Space on SE 14th

6201-6221 SE 14Th St, Des Moines, IA 50320

Highly visible retail space in revitalized corridor, flexible options.

  • Highly visible location on SE 14th Street (Hwy 69) with over 25,000 vehicles per day.
  • Flexible floorplan options from 1,400 SF up to 5,250 SF.
  • Join a revitalized retail corridor near Target, Hy‑Vee, and the redeveloping Southridge Mall.
  • Easy access & ample parking in front and rear of building.
  • Pylon signage available with excellent street visibility.
Updated: Jan 30
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Office Space Near Sculpture Park
$12 SF/Yr
6,401 SF

Office Space Near Sculpture Park

Office space with exposed brick near restaurants and sculpture park.

1300 Walnut St, Des Moines, IA 50309
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East Euclid Avenue Flex Space
$12 SF/Yr
8,500 SF

East Euclid Avenue Flex Space

Former tire service center suitable for auto, retail, or flex.

1566 East Euclid Ave, Des Moines, IA 50313
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Des Moines Flex Space Available
$8 SF/Yr
3,200 SF

Des Moines Flex Space Available

3,356 SF flex space with mezzanine office in Des Moines.

2100 Dixon St, Des Moines, IA 50316
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Class A Office Retail Building
$8 SF/Yr
158,557 SF

Class A Office Retail Building

Eight-story Class A office and retail building in downtown Des Moines.

400 Locust St, Des Moines, IA 50309
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Des Moines Flex Space Available
$6 SF/Yr
7,204 SF

Des Moines Flex Space Available

Multi-tenant flex building near Des Moines CBD with ample parking.

600 Southwest 7Th St, Des Moines, IA 50309
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Retail Space with Ample Parking
$13 SF/Yr
1,587 SF

Retail Space with Ample Parking

Retail space with high visibility and ample parking.

550 SW 9Th St, Des Moines, IA 50319
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East Village Mixed-Use Retail Space
$14 SF/Yr
2,639 SF

East Village Mixed-Use Retail Space

New retail space in a mixed-use East Village development.

201 Southeast 6Th St, Des Moines, IA 50309
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Retail Space Near Sculpture Park
$4,400 / Mo
2,450 SF

Retail Space Near Sculpture Park

Retail space for rent near downtown attractions and office buildings.

1301 Locust St, Des Moines, IA 50309
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Ingersoll Avenue Retail Opportunity
Contact for pricing
11,257 SF

Ingersoll Avenue Retail Opportunity

Retail space available in redeveloped Des Moines shopping center.

2700 Ingersoll Ave, Des Moines, IA 50312
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Ingersoll Avenue Retail Opportunity
$20 SF/Yr
6,270 SF

Ingersoll Avenue Retail Opportunity

Retail space in Soll Apartments, close to Des Moines CBD.

2301 Ingersoll Ave, Des Moines, IA 50312
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Retail Space on Court Avenue
$25 SF/Yr
2,780 SF

Retail Space on Court Avenue

Retail space available for lease in Des Moines, Iowa.

420 Court Ave, Des Moines, IA 50309
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Des Moines Office Space Available
$14 SF/Yr
7,576 SF

Des Moines Office Space Available

7576 square foot office space for rent.

304 15Th St, Des Moines, IA 50309
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Des Moines Flex Space Available
$5 SF/Yr
8,344 SF

Des Moines Flex Space Available

Multi-tenant flex building with stable power and convenient location.

601 Southwest 9Th St, Des Moines, IA 50309
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Retail/Office Space in Mixed-Use Building
$18 SF/Yr
4,539 SF

Retail/Office Space in Mixed-Use Building

Trendy retail or office space in a modern urban neighborhood.

210 Southwest 11Th St, Des Moines, IA 50309
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Retail/Office Space Near Airport
$10 SF/Yr
2,400 SF

Retail/Office Space Near Airport

Affordable retail or office space with convenient access to downtown.

2017 Southlawn Dr, Des Moines, IA 50315
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Grand Avenue Office Space Available
$10 SF/Yr
8,971 SF

Grand Avenue Office Space Available

Highly visible office building in the Grand Avenue corridor.

2141 Grand Ave, Des Moines, IA 50312
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Modern Retail Space Available
$22 SF/Yr
2,950 SF

Modern Retail Space Available

Highly visible retail space with excellent signage opportunities.

4814 Southwest 9Th St, Des Moines, IA 50315
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New Mixed-Use Building on Ingersoll
$30 SF/Yr
2,609 SF

New Mixed-Use Building on Ingersoll

New mixed-use building on busy street with high traffic.

2701 Ingersoll Ave, Des Moines, IA 50312
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Retail Space in Mixed-Use Building
$10 SF/Yr
1,327 SF

Retail Space in Mixed-Use Building

Retail space available in a mixed-use building.

1938 Southeast 6Th St, Des Moines, IA 50315
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Retail Space Near Des Moines Airport
$15 SF/Yr
5,793 SF

Retail Space Near Des Moines Airport

Well-maintained retail space near Des Moines International Airport.

4210-4214 Fleur Dr, Des Moines, IA 50321
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Explore Similar Spaces for Sale in Des Moines, IA

Consider Similar Space for Sale. We found 208 Spaces in Nearby Locations matching your search parameters.

Adaptable Commercial Space, Des Moines/Ankeny
$950,000
1.86 Acres

Adaptable Commercial Space, Des Moines/Ankeny

Renovated commercial space suitable for retail, office, or service businesses.

1380 NE 66Th Ave, Des Moines, IA 50313
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Des Moines, IA Commercial real estate Leasing Opportunities Market Analysis

Explore Commercial real estate leasing options in Des Moines, IA with 410 listings featured on our commercial real estate exchange. The current inventory includes 161,274,758,040 square feet of properties with an estimated lease value of $1,068 /Mo.

Estimated lease rates for Commercial real estate in Des Moines, IA begin at $1.50 SF/Yr, with an average of $14 SF/Yr and extend to $34 SF/Yr.
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