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Charleston, SC Commercial Real Estate for Lease

237 results
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Downtown Charleston
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Downtown Charleston

170 Floors, Charleston, SC 29401

Flexible workspace in Las Colinas MacArthur

  • Be part of a vibrant coworking community with dedicated desk or hot desking options in thousands of idyllic locations across the globe
  • Grow in a modern workplace with the added advantage of a benefits program offering exclusive discounts and bespoke procurement support
  • Access Regus' network of workspaces and business lounges as often as you need and take advantage of their exclusive benefits
  • Impress clients, hold memorable workshops, and deliver a winning pitch in Regus' meeting spaces, fully equipped for gatherings of any size
  • Collaborate with like‑minded professionals and enjoy regular networking and community events with a Regus membership
Updated: Feb 19
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Retail Space in James Island
$36 SF/Yr
90,993 SF

Retail Space in James Island

1739 Maybank Hwy, Charleston, SC 29412

Retail space for lease in a high-traffic shopping center.

  • Prime corner location at the intersection of Maybank Highway and Folly Road.
  • High traffic intersection with 30,700 VPD on Maybank Hwy & 29,600 VPD on Folly Rd.
  • Anchor tenants include Harris Teeter, CVS, and Pet Supplies Plus.
  • Easy access with multiple entrances from both Maybank Highway and Folly Road.
  • Less than 10 minutes from downtown Charleston and less than 5 minutes from Highway 17.
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Prime Retail Space on King
$75 SF/Yr
3,740 SF

Prime Retail Space on King

High-profile retail space in Charleston's premier shopping destination.

229 King St, Charleston, SC 29401
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Benefitfocus Way Office Space Sublease
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Benefitfocus Way Office Space Sublease

Office spaces for sublease in two buildings near I-526.

215 Benefitfocus Way, Charleston, SC 29492
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Furnished Office Building Sublease Opportunity
$24 SF/Yr
78,394 SF

Furnished Office Building Sublease Opportunity

Well-appointed, fully furnished office building available for sublease on Daniel Island.

125 Fairchild St, Charleston, SC 29492
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Charleston Historic District Office Space
$22 SF/Yr
16,816 SF

Charleston Historic District Office Space

Renovated office suites with harbor views in Charleston's historic district.

2 Cumberland St, Charleston, SC 29401
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Renovated Retail Space on King
$23 SF/Yr
2,000 SF

Renovated Retail Space on King

Recently renovated retail space with high foot traffic and parking.

577 King St, Charleston, SC 29401
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Clements Ferry Road Office Space
$20 SF/Yr
1,010 SF

Clements Ferry Road Office Space

Second floor office space available for rent in Charleston.

2414 Clements Ferry Rd, Charleston, SC 29492
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Downtown Charleston Office with Drive-Thru
$37 SF/Yr
1,978 SF

Downtown Charleston Office with Drive-Thru

Turn-key office space with parking and drive-thru in Charleston.

172 Ashley Ave, Charleston, SC 29401
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Office Space on Jessen Lane
$20 SF/Yr
1,500 SF

Office Space on Jessen Lane

Highly visible office space in a rapidly growing commercial corridor.

405 Jessen Ln, Charleston, SC 29492
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Retail Space Near College
$45 SF/Yr
2,030 SF

Retail Space Near College

Retail spaces for lease near the College of Charleston.

55 George St, Charleston, SC 29401
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Savannah Highway Retail/Office Building
$16 SF/Yr
2,800 SF

Savannah Highway Retail/Office Building

Free-standing 2,800 SF retail or office building for lease.

2413 Savannah Hwy, Charleston, SC 29414
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Retail Space on Folly Road
$26 SF/Yr
640 SF

Retail Space on Folly Road

Retail space for lease in a high-traffic shopping center.

915 Folly Rd, Charleston, SC 29412
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West Ashley Medical Office Space
$22 SF/Yr
3,000 SF

West Ashley Medical Office Space

3,000 SF office space in the heart of West Ashley.

1027 Physicians Dr, Charleston, SC 29414
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Downtown Charleston Office Space Available
$25 SF/Yr
2,040 SF

Downtown Charleston Office Space Available

Office suites for lease in downtown Charleston's office district.

180 Meeting St, Charleston, SC 29401
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Retail Space on Rivers Avenue
$17 SF/Yr
1,600 SF

Retail Space on Rivers Avenue

Retail space available in a busy Charleston strip center.

8510 Rivers Ave, Charleston, SC 29406
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Retail Space on Savannah Highway
$19 SF/Yr
3,044 SF

Retail Space on Savannah Highway

High-visibility retail center with ample parking and heavy traffic.

1649 Savannah Hwy, Charleston, SC 29407
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Downtown Retail Space For Lease
$30 SF/Yr
1,363 SF

Downtown Retail Space For Lease

New retail spaces available in downtown Charleston apartment community.

1310 Meeting St, Charleston, SC 29403
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Renovated Office Space on King
$23 SF/Yr
2,631 SF

Renovated Office Space on King

Renovated office space in Charleston's 'Dine & Design' district.

579 King Street Ext, Charleston, SC 29403
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Wappoo Creek Office Space Available
$20 SF/Yr
2,944 SF

Wappoo Creek Office Space Available

Office space for lease in a convenient Charleston location.

125 Wappoo Creek Dr, Charleston, SC 29412
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Downtown Charleston Office Space
$29 SF/Yr
1,650 SF

Downtown Charleston Office Space

Office space for rent in Charleston's growing Upper Peninsula.

11 Isabella St, Charleston, SC 29403
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Corner Office Space Available
Contact for pricing
1,658 SF

Corner Office Space Available

Office space for rent located on a prominent corner.

852 Orleans Rd, Charleston, SC 29407
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Class A Office Space Available
$22 SF/Yr
20,028 SF

Class A Office Space Available

Class A office suite for lease in growing Daniel Island/Cainhoy.

1951 Clements Ferry Rd, Charleston, SC 29492
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Class A Office Sublease
$38 SF/Yr
10,499 SF

Class A Office Sublease

Class A office space available for sublease in Charleston, SC.

100 Calhoun St, Charleston, SC 29401
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Charleston, SC Commercial real estate Leasing Opportunities Market Analysis

Explore Commercial real estate leasing options in Charleston, SC with 366 listings featured on our commercial real estate exchange. The current inventory includes 93,338,364,240 square feet of properties with an estimated lease value of $80,912.

Estimated lease rates for Commercial real estate in Charleston, SC begin at $8 SF/Yr, with an average of $652 /Mo and extend to $45,000.
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