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    Charleston, SC Commercial Real Estate for Lease

    243 results
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    Downtown Charleston
    Contact for pricing

    Downtown Charleston

    Discover many ways to work your way in Downtown Charleston

    170 Floors, Charleston, SC 29401
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    Charleston Historic District Office Space
    $22 SF/Yr

    Charleston Historic District Office Space

    2 Cumberland St, Charleston, SC 29401

    Renovated office suites with harbor views in historic Charleston.

    • Rare views of Charleston Harbor, Ravenel Bridge, US Customs House, and USS Yorktown.
    • Newly renovated suites with modern finishes ready for immediate occupancy.
    • Located in the historic district of Charleston's peninsula.
    • Open floorplans provide functional versatility.
    • Suites available on the 2nd and 3rd floors, each with 4,204 RSF.
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    Downtown Charleston Freestanding Building
    $29 SF/Yr

    Downtown Charleston Freestanding Building

    276 East Bay St, Charleston, SC 29401

    Freestanding building in historic downtown Charleston for lease.

    • Prime location in historic downtown Charleston, near East Bay Harris Teeter and Ansonborough Inn.
    • ±14,518 SF freestanding building with flexible use options: retail, office, or restaurant.
    • Rare on‑site parking with 38 spaces.
    • High traffic volume: 28,300 VPD on East Bay (SCDOT 2024) and high walkability score of 83%.
    • Proximity to Union Pier mixed‑use development and future College of Charleston Business School.
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    James Island Office Space Available
    $20 SF/Yr

    James Island Office Space Available

    Office space for lease in a convenient Charleston location.

    125 Wappoo Creek Dr, Charleston, SC 29412
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    Prime Retail Space on George
    $45 SF/Yr

    Prime Retail Space on George

    Retail space for lease in downtown Charleston near King Street.

    51 George St, Charleston, SC 29401
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    Whole Foods Anchored Shopping Center
    Contact for pricing

    Whole Foods Anchored Shopping Center

    Premier shopping center in West Ashley with high-traffic location.

    1133 Savannah Hwy, Charleston, SC 29407
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    Furnished Office Building Sublease Opportunity
    $24 SF/Yr
    78,394 SF

    Furnished Office Building Sublease Opportunity

    Well-appointed, fully furnished office building available for sublease on Daniel Island.

    125 Fairchild St, Charleston, SC 29492
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    Charleston Historic District Office Space
    $22 SF/Yr
    16,816 SF

    Charleston Historic District Office Space

    Renovated office suites with harbor views in Charleston's historic district.

    2 Cumberland St, Charleston, SC 29401
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    Retail Space in James Island
    $38 SF/Yr

    Retail Space in James Island

    Retail space for lease in a high-traffic shopping center.

    1739 Maybank Hwy, Charleston, SC 29412
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    Prime Retail Space on King
    $75 SF/Yr
    3,740 SF

    Prime Retail Space on King

    High-profile retail space in Charleston's premier shopping destination.

    229 King St, Charleston, SC 29401
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    Daniel Island Office/Medical Opportunity
    Contact for pricing
    3,047 SF

    Daniel Island Office/Medical Opportunity

    Office/Medical space in Publix-anchored Daniel Island shopping center.

    162 Seven Farms Dr, Charleston, SC 29492
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    Charleston Flex Retail Space
    Contact for pricing

    Charleston Flex Retail Space

    Flex retail space in established commercial corridor with high traffic.

    1436 Meeting Street Rd, Charleston, SC 29405
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    King Street Retail Space Available
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    King Street Retail Space Available

    Prime retail space in downtown Charleston's shopping corridor.

    338-A King Street Ext, Charleston, SC 29401
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    Retail Space in Growing Area
    Contact for pricing
    1,692 SF

    Retail Space in Growing Area

    Class-A retail space available in a neighborhood center anchored by Publix.

    730 Hopewell Dr, Charleston, SC 29492
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    King Street Retail Space Available
    $60 SF/Yr
    1,920 SF

    King Street Retail Space Available

    New retail space with patio on King Street.

    677 King Street Ext, Charleston, SC 29403
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    Prime Retail Space on King
    $75 SF/Yr

    Prime Retail Space on King

    High-profile retail space in downtown Charleston near Charleston Place.

    229 King St, Charleston, SC 29401
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    Class A Office Space Available
    $22 SF/Yr

    Class A Office Space Available

    Class A office suite for lease in growing Daniel Island/Cainhoy.

    1951 Clements Ferry Rd, Charleston, SC 29492
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    West Ashley Multi-Tenant Office Property
    $25 SF/Yr
    38,510 SF

    West Ashley Multi-Tenant Office Property

    Multi-tenant office property in West Ashley with suites available for lease.

    1460 Tobias Gadson Blvd, Charleston, SC 29407
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    Historic French Quarter Office Space
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    Historic French Quarter Office Space

    Charming 2,400 SF office in Charleston's French Quarter.

    46A Lodge Aly, Charleston, SC 29401
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    Benefitfocus Way Office Space Sublease
    Contact for pricing

    Benefitfocus Way Office Space Sublease

    Office spaces for sublease in two buildings near I-526.

    215 Benefitfocus Way, Charleston, SC 29492
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    Daniel Island Office Space Available
    $32 SF/Yr
    3,975 SF

    Daniel Island Office Space Available

    Second-floor office suite in Daniel Island's Town Center.

    115 River Landing Dr, Charleston, SC 29492
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    Class A Office Sublease
    $38 SF/Yr
    10,499 SF

    Class A Office Sublease

    Class A office space available for sublease in Charleston, SC.

    100 Calhoun St, Charleston, SC 29401
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    Prime Retail Space in Charleston
    $38 SF/Yr

    Prime Retail Space in Charleston

    Street-front retail with high ceilings, free parking, great visibility.

    601 Meeting Street Rd, Charleston, SC 29403
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    Explore Similar Spaces for Sale in Charleston, SC

    Consider Similar Space for Sale. We found 138 Spaces in Nearby Locations matching your search parameters.

    Charleston Medical Property Investment
    $1,895,000
    5,567 SF

    Charleston Medical Property Investment

    Thriving medical property in Charleston, SC with favorable lease terms.

    2039 Savannah Hwy, Charleston, SC 29407
    View details

    Charleston, SC Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Charleston, SC with 380 listings featured on our commercial real estate exchange. The current inventory includes 91,919,223,000 square feet of properties with an estimated lease value of $35,893.

    Estimated lease rates for Commercial real estate in Charleston, SC begin at $2 SF/Yr, with an average of $299 SF/Yr and extend to $32,000.
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