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    Charleston, SC Commercial Real Estate for Lease

    254 results
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    Downtown Charleston
    Contact for pricing

    Downtown Charleston

    170 Floors, Charleston, SC 29401

    Flexible workspace in Las Colinas MacArthur

    • Be part of a vibrant coworking community with dedicated desk or hot desking options in thousands of idyllic locations across the globe
    • Grow in a modern workplace with the added advantage of a benefits program offering exclusive discounts and bespoke procurement support
    • Access Regus' network of workspaces and business lounges as often as you need and take advantage of their exclusive benefits
    • Impress clients, hold memorable workshops, and deliver a winning pitch in Regus' meeting spaces, fully equipped for gatherings of any size
    • Collaborate with like‑minded professionals and enjoy regular networking and community events with a Regus membership
    Updated: Feb 19
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    Whole Foods Anchored Shopping Center
    Contact for pricing

    Whole Foods Anchored Shopping Center

    1133 Savannah Hwy, Charleston, SC 29407

    Premier shopping center in West Ashley with high-traffic location.

    • Anchored by a 45,164 SF Whole Foods Market, ensuring consistent, quality foot traffic.
    • Located in Charleston’s thriving West Ashley submarket on Savannah Highway.
    • Premier shopping center with a dynamic mix of retail, restaurant, and wellness tenants.
    • Fully Leased, providing immediate income.
    • High visibility from a major thoroughfare with multiple access points from Savannah Highway and robust parking.
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    Charleston Flex Retail Space
    Contact for pricing

    Charleston Flex Retail Space

    Flex retail space in established commercial corridor with high traffic.

    1436 Meeting Street Rd, Charleston, SC 29405
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    Downtown Charleston Office Space
    $29 SF/Yr

    Downtown Charleston Office Space

    Office space for rent in Charleston's growing Upper Peninsula.

    11 Isabella St, Charleston, SC 29403
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    Daniel Island Office/Medical Opportunity
    Contact for pricing
    3,047 SF

    Daniel Island Office/Medical Opportunity

    Office/Medical space in Publix-anchored Daniel Island shopping center.

    162 Seven Farms Dr, Charleston, SC 29492
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    Retail Space on Rivers Avenue
    $17 SF/Yr
    1,600 SF

    Retail Space on Rivers Avenue

    Retail space available in a busy Charleston strip center.

    8510 Rivers Ave, Charleston, SC 29406
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    Prime Retail Space on King
    $75 SF/Yr
    3,740 SF

    Prime Retail Space on King

    High-profile retail space in Charleston's premier shopping destination.

    229 King St, Charleston, SC 29401
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    Retail Space in James Island
    $36 SF/Yr

    Retail Space in James Island

    Retail space for lease in a high-traffic shopping center.

    1739 Maybank Hwy, Charleston, SC 29412
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    Benefitfocus Way Office Space Sublease
    Contact for pricing

    Benefitfocus Way Office Space Sublease

    Office spaces for sublease in two buildings near I-526.

    215 Benefitfocus Way, Charleston, SC 29492
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    Furnished Office Building Sublease Opportunity
    $24 SF/Yr
    78,394 SF

    Furnished Office Building Sublease Opportunity

    Well-appointed, fully furnished office building available for sublease on Daniel Island.

    125 Fairchild St, Charleston, SC 29492
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    Charleston Historic District Office Space
    $22 SF/Yr
    16,816 SF

    Charleston Historic District Office Space

    Renovated office suites with harbor views in Charleston's historic district.

    2 Cumberland St, Charleston, SC 29401
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    King Street Retail Space Available
    $60 SF/Yr
    1,920 SF

    King Street Retail Space Available

    New retail space with patio on King Street.

    677 King Street Ext, Charleston, SC 29403
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    Class A Office Space Available
    $22 SF/Yr

    Class A Office Space Available

    Class A office suite for lease in growing Daniel Island/Cainhoy.

    1951 Clements Ferry Rd, Charleston, SC 29492
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    Corner Office Space Available
    Contact for pricing
    1,658 SF

    Corner Office Space Available

    Office space for rent located on a prominent corner.

    852 Orleans Rd, Charleston, SC 29407
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    Class A Office Sublease
    $38 SF/Yr
    10,499 SF

    Class A Office Sublease

    Class A office space available for sublease in Charleston, SC.

    100 Calhoun St, Charleston, SC 29401
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    Office Complex on 10.82 Acres
    $24 SF/Yr
    9,275 SF

    Office Complex on 10.82 Acres

    Three-building office complex with large parking field on 10.82 acres.

    1 South Park Cir, Charleston, SC 29407
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    Downtown Charleston Office Space Available
    $25 SF/Yr
    2,040 SF

    Downtown Charleston Office Space Available

    Office suites for lease in downtown Charleston's office district.

    180 Meeting St, Charleston, SC 29401
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    Office Space on Jessen Lane
    $20 SF/Yr
    1,500 SF

    Office Space on Jessen Lane

    Highly visible office space in a rapidly growing commercial corridor.

    405 Jessen Ln, Charleston, SC 29492
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    Office Space with Harbor Views
    $22 SF/Yr
    1,600 SF

    Office Space with Harbor Views

    Corner office suite with views of Charleston Harbor available for rent.

    3 Lockwood Dr, Charleston, SC 29401
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    Historic Downtown Charleston Office Space
    $30 SF/Yr
    2,851 SF

    Historic Downtown Charleston Office Space

    Recently renovated office space in historic downtown Charleston.

    11 Broad St, Charleston, SC 29401
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    Upper King Street Office Space
    $34 SF/Yr
    3,204 SF

    Upper King Street Office Space

    Office space for rent in Charleston's Upper King District.

    463 King Street Ext, Charleston, SC 29403
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    Prime Retail Space on King
    $75 SF/Yr

    Prime Retail Space on King

    High-profile retail space in downtown Charleston near Charleston Place.

    229 King St, Charleston, SC 29401
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    Explore Similar Spaces for Sale in Charleston, SC

    Consider Similar Space for Sale. We found 139 Spaces in Nearby Locations matching your search parameters.

    Charleston Medical Property Investment
    $1,895,000
    5,567 SF

    Charleston Medical Property Investment

    Thriving medical property in Charleston, SC with favorable lease terms.

    2039 Savannah Hwy, Charleston, SC 29407
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    Renovated Duplex in Downtown Charleston
    $925,000
    1,461 SF

    Renovated Duplex in Downtown Charleston

    Turnkey duplex near MUSC & CofC, completed renovation in 2025.

    68 Lee St, Charleston, SC 29403
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    Charleston, SC Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Charleston, SC with 392 listings featured on our commercial real estate exchange. The current inventory includes 93,338,364,240 square feet of properties with an estimated lease value of $80,912.

    Estimated lease rates for Commercial real estate in Charleston, SC begin at $8 SF/Yr, with an average of $652 /Mo and extend to $45,000.
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    Browse Commercial real estate for Lease Near Charleston, SC

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