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Former Medical Office and Community Space
For Sale
$1,750,000

6635 E 21st Street, Indianapolis, IN 46219

Former medical office with ADA-accessible layout, multiple entrances, and ample off-street parking.

Property Size7,548 SF
Price / SF$231.85
Days on Market41

Property Features for 6635 E 21st Street

General Information

Standard status Active
Size 7,548 SF
Total Parking Spaces 50
Zoning C-1

Additional Details

Highway Access Yes

Amenities

Attached, Common

Building Details

Building Size 7,548 SF
Stories 1
Listing Agency: Keller Williams Indy South
Listed By: Shelly Johnson · License #RB14043056
Source: Evrealestate
Added: Jul 15 Changed: Aug 24 Last Checked: Aug 23 at 2:23AM

Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of Keller Williams Indy South

Investment Insights

Based on property information with market context.

This former medical office building provides a flexible, ADA-accessible interior with room for multiple uses. The layout includes three private offices, a conference room, break room, a large waiting area, and a substantial open room that could support a variety of professional or community functions. The property also has four restrooms. Recent improvements are noted throughout, including a new roof, new water heater, eight gas furnaces and AC units, motion-sensored flood lights, new LED lighting, and a resurfaced parking lot.

The property includes multiple entrances and two parking lots with nearly 50 spaces, supporting access for staff, clients, and visitors. It is located along East 21st Street on Indianapolis’ east side with convenient connectivity to I-70/Shadeland Avenue, providing straightforward access to downtown Indianapolis, I-465, and surrounding Central Indiana communities.

The building’s configuration—private offices, restrooms, and a large open room—can accommodate both appointment-based and gathering-style environments, depending on the tenant’s operational needs.

Key Highlights

  • 7,548 SF former medical office built in 1990 with an ADA‑accessible layout
  • Flexible interior layout with three private offices, conference room, break room, and large waiting area plus a huge open room
  • Four restrooms including multiple private office and meeting/break spaces

Financial Insights

Estimated NOI and Cap Rate

NOI = area × lease_rate × (100 − vacancy) / 100 × (1 − expense_ratio). Net Operating Income — what the owner takes home each year before mortgage payments and income tax. Effective rent (asking rent minus vacancy losses) minus operating costs (taxes, insurance, maintenance, management).
NOI / Yr
$99,996
Cap rate = NOI / list price × 100. Capitalization rate — annual return on a fully cash purchase, before financing. NOI divided by price. Higher means more income per dollar invested, but usually also more risk or older condition. 5–8% is typical for stabilized commercial property; double digits often signal distressed deals.
Cap Rate
5.71%
Suggested Prices Based on Cap Rates Cap rates vary significantly by property type, market, and asset quality. Typical U.S. stable-market ranges: Multifamily — 4.5% to 6.5% (Class A in primary markets often sub-5%; Class C in secondary markets 6%+) Industrial / Logistics — 5.0% to 7.0% (compressed heavily in recent years due to e-commerce demand) Office — 6.5% to 9%+ (wide spread post-2020; CBD Class A vs. suburban Class B varies dramatically) Retail — 5.5% to 8.5% (grocery-anchored on the low end, unanchored strip centers higher) Hospitality / Hotels — 7.5% to 10%+ (higher due to operational risk) Self-Storage — 5.5% to 7.5% Medical Office — 6.0% to 7.5% Net Lease (single tenant, credit) — 5.0% to 7.0% depending on tenant credit and lease term Rules of thumb: Primary markets (NYC, SF, LA, Boston, DC) trade at lower cap rates than secondary/tertiary markets, often by 100–200 bps (bps, aka basis points; 1 bp = 0.01%). Class A assets trade ~50–150 bps tighter than Class B, and Class B tighter than Class C. Cap rates move inversely with price — a lower cap rate means a higher price for the same NOI. Spread to the 10-year Treasury is a common benchmark; historically 200–400 bps over the 10-year.
Cap Rate 5%
$1,999,920 $2.0M
Cap Rate 7%
$1,428,514 $1.4M
Cap Rate 9%
$1,111,067 $1.1M
Market Conditions
NOI Build-Up for 7,548 SF Vacancy — income lost from leasable area expected to sit empty during the year, subtracted from gross rent. EGI (Effective Gross Income) — gross rent minus vacancy losses, the realistic income before paying operating costs. OpEx (Operating Expenses) — recurring costs to operate the property (property tax, insurance, utilities, maintenance, management); excludes financing and capital improvements. NOI (Net Operating Income) — income a property generates after operating costs but before financing and taxes.
Gross rent
$181.2K $24.00/SF
− Vacancy
−$14.5K −$1.92/SF
EGI
$166.7K $22.08/SF
− OpEx
−$66.7K −$8.83/SF
NOI
$100.0K $13.25/SF
Area
Indianapolis, IN
Vacancy
8.00%
Lease Rate
$24.00 /SF/Yr
Expense Ratio
40.00%
Simulate Cap Rate and NOI
Suggested Prices Based on Cap Rates Cap rates vary significantly by property type, market, and asset quality. Typical U.S. stable-market ranges: Multifamily — 4.5% to 6.5% (Class A in primary markets often sub-5%; Class C in secondary markets 6%+) Industrial / Logistics — 5.0% to 7.0% (compressed heavily in recent years due to e-commerce demand) Office — 6.5% to 9%+ (wide spread post-2020; CBD Class A vs. suburban Class B varies dramatically) Retail — 5.5% to 8.5% (grocery-anchored on the low end, unanchored strip centers higher) Hospitality / Hotels — 7.5% to 10%+ (higher due to operational risk) Self-Storage — 5.5% to 7.5% Medical Office — 6.0% to 7.5% Net Lease (single tenant, credit) — 5.0% to 7.0% depending on tenant credit and lease term Rules of thumb: Primary markets (NYC, SF, LA, Boston, DC) trade at lower cap rates than secondary/tertiary markets, often by 100–200 bps (bps, aka basis points; 1 bp = 0.01%). Class A assets trade ~50–150 bps tighter than Class B, and Class B tighter than Class C. Cap rates move inversely with price — a lower cap rate means a higher price for the same NOI. Spread to the 10-year Treasury is a common benchmark; historically 200–400 bps over the 10-year.
Cap Rate 5%
$1,999,920
Cap Rate 7%
$1,428,514
Cap Rate 9%
$1,111,067

Alternative Uses

Best Use
Healthcare Medical
$1.43M
$1.25M – $1.67M (±1% cap)
NOI $99,996 @ 7.0% cap · market cap 5.71%
Second Best
Office B
$1.42M
$1.25M – $1.66M (±1% cap)
NOI $99,656 @ 7.0% cap · market cap 5.69%
Theoretical Best
Office A
$1.88M
$1.64M – $2.19M (±1% cap)
NOI $131,516 @ 7.0% cap · market cap 7.52%
Zoning and permitted uses should be independently verified with authorities.

Property Analytics

Current Use

Dr. Megan O'bryan Physician Fiducial Business Centers, ... Consultant RCG Indianapolis Medical Clinic Meliyah Harris Counselor Samantha Saxman Physician

Suggested Use

Top Pick Real Estate Agency Law Firm Dental Office Electrical Service Garden Center Kitchen & Bath Showroom

Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.

Lease Details

Yes
Highway access

Location Intelligence

Trade Area within ½ mile

552
Businesses Nearby
Under-served
Demand for This Use

Demographics for 46219, IN

36,556
Population
17,028
Households
2.1
Avg Household Size
38
Median Age
26%
College-Educated
86%
High-School Grad
13.0 sq mi
ZIP Area
2,812
Density / Sq Mi
$57,811
Median Household Income
$38,995
Median Earnings
$991
Median Rent
$177,000
Median Home Value

Market

Vacancy Rate% for Office in Indianapolis, IN

17.4% 2019
17.8% 2020
19.1% 2021
19.3% 2022
22.2% 2023
22.8% 2024
21.4% 2025
Rey
Questions? Ask Rey
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Frequently Asked Questions

What type of property is this?
Medical Office Space - Former medical office with ADA-accessible layout, multiple entrances, and ample off-street parking.
Where is this medical office space located?
The property is located at 6635 E 21st Street Indianapolis, IN.
What is the asking price?
The asking price for this property is $1,750,000.
What are key features of this property?
This property features: 7,548 SF former medical office built in 1990 with an ADA‑accessible layout; Flexible interior layout with three private offices, conference room, break room, and large waiting area plus a huge open room; Four restrooms including multiple private office and meeting/break spaces
More about this property
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