Search
Howell Health Hub Office Space
For Lease
$19 SF/Yr

645 W Grand River, Howell, MI 48843

Professional and medical office building near Downtown Howell, Michigan.

Space Size108,000 SF
Days on Market287

Property Features for 645 W Grand River

General Information

Standard status Active
Size 108,000 SF
Class B
Property subtype Office
Lease Term NNN

Building Details

Building Size 108,231 SF
Year Built 1956

Spaces For Lease

at 645 W Grand River Contact us

645 W. Grand River $19/SF/Yr

Size
108,000 SF
Term
Negotiable
Contact us
Listing Agency: Thomas Duke Company
Listed By: John Porth · License #6501336460
Source: Thomasduke
Added: Nov 24, 2025 Changed: Sep 5 Last Checked: Sep 7 at 5:18AM

Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of Thomas Duke Company

Investment Insights

Based on property information with market context.

Located at 645 W. Grand River Avenue, the Howell Health Hub is a well-established professional and medical office building near Downtown Howell, Michigan. The building spans 108,231 square feet across three stories and sits on 5.33 professionally landscaped acres. The property features an expansive 400-space surface parking lot, recent improvements to the roof and HVAC system, and a full-building backup generator. Well-maintained, built-out space from 4,000 to 80,000 square feet is immediately available for occupancy. Office amenities and features include an attended lobby entrance, conference rooms, natural-light-filled private perimeter offices, and primarily open floor plans, allowing for ample space for individual workstations. Situated on the south side of the Grand River at Byron Road, 645 W Grand River Avenue is just west of Michigan Avenue and within walking distance to downtown. Tenants and guests are close to Diamonds Steaks and Seafood, Uptown Coffeehouse, M Street Baking Company, 2FOG’s Pub, the Historic Howell Theater, the Livingston County Courthouse, and more. Route 59 and I-96 provide easy highway accessibility.

Key Highlights

  • Large, well‑maintained office spaces (4,000‑80,000 sq ft) immediately available.
  • Located near Downtown Howell, offering convenient access to amenities and attractions.
  • Expansive 400‑space surface parking lot.

Property Analytics

Current Use

York Risk Services Insurance Agency The Steele Real Estate ... Real Estate Agency Julie Tucker, Realtor Real Estate Agency Elena Krumrei - REALTOR® ... Real Estate Agency Team Murphy Real ... Real Estate Agency

Suggested Use

Top Pick Grocery & Convenience Store (Bike/Boat/Book/etc) Store Storage Facility Nail Salon Carpet & Flooring Store Locksmith

Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.

Lease Details

NNN (Triple Net)
Lease Type
$2.85 /SF/Yr
CAM

Location Intelligence

Trade Area within ½ mile

800
Businesses Nearby

Demographics for 48843, MI

47,704
Population
19,001
Households
2.5
Avg Household Size
41
Median Age
37%
College-Educated
95%
High-School Grad
89.6 sq mi
ZIP Area
532
Density / Sq Mi
$91,620
Median Household Income
$48,613
Median Earnings
$1,221
Median Rent
$323,100
Median Home Value

Market

Vacancy Rate% for Office in Midwest region

13.7% 2019
15.6% 2020
17.1% 2021
18.9% 2022
21% 2023
22% 2024
21.3% 2025
Rey
Questions? Ask Rey
Realmo’s AI knows this listing — price, zoning, demand, history. Ask anything.

Frequently Asked Questions

What type of property is this?
Office building - Professional and medical office building near Downtown Howell, Michigan.
Where is this office building located?
The property is located at 645 W Grand River Howell, MI.
What is the lease rate?
The lease rate is $19 SF/Yr.
What are key features of this property?
This property features: Large, well‑maintained office spaces (4,000‑80,000 sq ft) immediately available.; Located near Downtown Howell, offering convenient access to amenities and attractions.; Expansive 400‑space surface parking lot.
More about this property
Thanks! Your message was sent.
Error! Your message wasn't sent.
Please enter your name
Please enter email
Please enter the email in the correct format
Please enter phone
Please enter the number in the correct format
Please enter message