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Class AA Medical Office Building
For Lease
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5115 Fannin Street, Houston, TX 77004

153,775 SF, 10-story medical office building for lease.

Space Size1,933 SF - 10,342 SF
Days on Market288

Property Features for 5115 Fannin Street

General Information

Standard status Active
Size 1,933 SF - 10,342 SF
Property subtype Healthcare

Spaces For Lease

at 5115 Fannin Street Contact us

Suite 101

Size
6,021 SF
Availability
Available
Contact us

Suite 102

Size
1,933 SF
Availability
Available
Contact us

Suite 750

Size
10,342 SF
Availability
Available
Contact us
Listing Agency: CBRE, Inc.
Listed By: Brandy Bellow Spinks
Source: Cbre
Added: Nov 22, 2025 Changed: Sep 5 Last Checked: Sep 6 at 6:08AM

Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of CBRE, Inc.

Investment Insights

Based on property information with market context.

This Class AA medical office building offers 153,775 square feet of space across 10 stories. The building includes first-floor medical space, five levels of structured parking, and four additional floors of medical space. Architectural features include a 7th-floor terrace with city views. The property is located in the Museum District, between the Texas Medical Center and Houston's Central Business District. It is accessible from I-69/US 59, State Highway 288, and Main Street, and is conveniently located near the METRORail between Fannin and San Jacinto, flanked by Palm Street and Southmore.

Key Highlights

  • Class AA Medical Office Building with 153,775 SF of medical space.
  • Convenient access to I‑69/US 59, State Highway 288 and Main Street.
  • Located in the Museum District between the Texas Medical Center and Houston CBD.

Property Analytics

Current Use

The Museo Institute for Medical ... Medical Clinic Museo Institute for Medical ... Corporate Office Hannah Muniz Castro Ophthalmologist George Basu, MD Physician Oscar Rosales, MD Physician

Suggested Use

Top Pick Auto Parts Store HVAC Service Bakery Electrical Service Locksmith Home Appliance Store

Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.

Lease Details

NNN (Triple Net)
Lease Type

Location Intelligence

Trade Area within ½ mile

2,855
Businesses Nearby
Under-served
Demand for This Use

Demographics for 77004, TX

37,005
Population
18,321
Households
2
Avg Household Size
31
Median Age
57%
College-Educated
96%
High-School Grad
5.2 sq mi
ZIP Area
7,116
Density / Sq Mi
$65,901
Median Household Income
$55,909
Median Earnings
$1,320
Median Rent
$384,100
Median Home Value

Market

Vacancy Rate% for Office in Houston, TX

21.3% 2019
24.5% 2020
25.2% 2021
26% 2022
25.3% 2023
25.5% 2024
24.8% 2025
Rey
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Similar Off Market Nearby

  • Skyline Animal Hospital 5108 Almeda Rd, Houston, TX 77004
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  • PetWell Partners 4203 Yoakum Blvd Suite 250, Houston, TX 77006

Frequently Asked Questions

What type of property is this?
Medical Office Space - 153,775 SF, 10-story medical office building for lease.
Where is this medical office space located?
The property is located at 5115 Fannin Street Houston, TX.
What are key features of this property?
This property features: Class AA Medical Office Building with 153,775 SF of medical space.; Convenient access to I‑69/US 59, State Highway 288 and Main Street.; Located in the Museum District between the Texas Medical Center and Houston CBD.
More about this property
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