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Three-Story Medical Office Building
For Lease
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500 E Main St, Columbus, OH 43215

Move-in ready medical suites with a newly renovated lobby and covered patient drop-off.

Property Size4,840 SF
Days on Market515

Property Features for 500 E Main St

General Information

Standard status Active
Size 4,840 SF
Net Rentable 55,844 SF
Property subtype OFFICE

Space & Availability

Available Space 55,844 SF
Space Use Medical Office
Condition Move-in Ready

Additional Details

Highway Access Yes

Amenities

Newly renovated lobby
Covered patient drop-off
On-site parking
Professional management
Architectural space planning

Building Details

Stories 3
Listing Agency: JLL | Columbus
Listed By: Joey Lamb · License #SAL.2021005923
Source: Moodyscre
Added: Mar 6, 2025 Changed: Jul 30 Last Checked: Aug 2 at 12:59PM

Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of JLL | Columbus

Investment Insights

Based on property information with market context.

This three-story medical office building offers move-in ready medical suites designed for patient-serving workflows. The property features a newly renovated lobby and covered patient drop-off, helping support convenient arrivals. Ample on-site parking is available for staff and visitors, and walkable amenities add day-to-day convenience for tenants and patients.

Located in the heart of downtown with convenient highway access, the building is positioned near Nationwide Children’s Hospital Main Campus and OhioHealth Grant Medical Center. That proximity can help simplify commutes and strengthen access for referrals and patient care teams.

Professional management and architectural space planning are available to support tenant buildout needs. The building also offers tenant improvement (TI) packages to help facilitate customized medical suite arrangements.

Key Highlights

  • Three floors of move‑in ready medical suites
  • Newly renovated lobby
  • Covered patient drop‑off

Property Analytics

Current Use

Zimmer Inc Industrial Manufacturer OhioHealth Laboratory Services ... Medical Laboratory Fat Pat's BBQ Restaurant Dr. James B. ... Physician Downtown Laboratory Patient ... Medical Laboratory

Suggested Use

Top Pick Electrical Service Auto Parts Store (Bike/Boat/Book/etc) Store Grocery & Convenience Store Furniture & Home Goods Kitchen & Bath Showroom

Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.

Lease Details

Yes
Highway access
NNN (Triple Net)
Lease Type

Location Intelligence

Trade Area within ½ mile

5,960
Businesses Nearby
Under-served
Demand for This Use

Demographics for 43215, OH

20,761
Population
13,428
Households
1.5
Avg Household Size
32
Median Age
71%
College-Educated
97%
High-School Grad
5.1 sq mi
ZIP Area
4,071
Density / Sq Mi
$74,469
Median Household Income
$59,521
Median Earnings
$1,487
Median Rent
$508,300
Median Home Value

Market

Lease Benchmarks for Columbus, OH

$12.58 /SF/Yr
Avg Asking Price
$0.7–$16.5 /SF/Yr
Price Range
12,518 SF
Avg Space Size

Vacancy Rate% for Office in Columbus, OH

14.1% 2019
20.2% 2020
23.4% 2021
26.3% 2022
25.6% 2023
24.1% 2024
23.5% 2025
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Frequently Asked Questions

What type of property is this?
Medical Office Space - Move-in ready medical suites with a newly renovated lobby and covered patient drop-off.
Where is this medical office space located?
The property is located at 500 E Main St Columbus, OH.
What are key features of this property?
This property features: Three floors of move‑in ready medical suites; Newly renovated lobby; Covered patient drop‑off
(614) 460-4403 Call to check price and availability
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