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    Medical Office Space Available Title is generated by Realmo AI

    500 E Main St, Columbus, OH 43215

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    Medical office space for lease in downtown Columbus.

    Type:office
    Property size:
    3,866 SF
    Added:
    Apr 15, 2026
    Days on Market:
    48
    Last Refresh:
    Apr 14 at 8:08 pm

    Property Features for 500 E Main St

    General Information

    Standard status
    Active
    Size
    3,866 SF
    Property subtype
    office

    Spaces For Lease

    at 500 E Main St Contact us

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    Listing Contact
    Andrew Dutcher
    Andrew Dutcher

    Listing agent Andrew Dutcher License #SAL.2007003283

    Listing office Columbus

    Listing date Apr 15, 2026

    Source Property.jll

    Displayed information is deemed reliable but is not guaranteed and should be independently verified.

    All listing content including descriptions, pricing, images are the copyrighted material of Columbus

    HighLights

    • Move‑in ready medical suites
    • Ample on‑site parking for staff and patients
    • Near Nationwide Children’s Hospital Main Campus and OhioHealth Grant Medical Center
    • Covered patient drop‑off area
    • Newly renovated lobby provides a welcoming atmosphere
    • Walkable amenities offer convenience for staff and visitors

    Overview

    Medical office space is available for lease at 500 E Main St. The available space ranges from 1,979 to 4,840 square feet within a 55,844 square foot building. The building has 3 floors and features move-in ready medical suites. A newly renovated lobby and covered patient drop-off area are present. Ample on-site parking is available. The property is located in the heart of downtown with convenient highway access and walkable amenities. It is near Nationwide Children’s Hospital Main Campus and OhioHealth Grant Medical Center.
    Location Intelligence

    Current Use by Public Records

    Zimmer Inc Industrial Manufacturer OhioHealth Laboratory Services ... Medical Laboratory Fat Pat's BBQ Restaurant Dr. James B. ... Physician Downtown Laboratory Patient ... Medical Laboratory

    Suggested Use

    Real Estate Agency Restaurant Spa & Massage Center Dental Office Hair Salon Law Firm Nail Salon Building Supply Auto Repair Shop Gym & Fitness Center

    Zoning and permitted uses should be independently verified with local authorities.

    Similar Places Nearby

    • Care Pet Clinic 785 E Main St, Columbus, OH 43205
    • The Veterinary Relief Company 341 S 3rd St suite 100-282, Columbus, OH 43215
    • MedVet columbus, oh 43215

    Location Insight

    • Map
    • Local Demand
    City
    Columbus
    County
    Delaware
    State
    Ohio
    Longitude
    -82.9862559
    Latitude
    39.9577977

    FAQs

    What type of property is this?
    Medical Office Space - Medical office space for lease in downtown Columbus.
    Where is this medical office space located?
    The property is located at 500 E Main St Columbus, OH.
    What are key features of this property?
    This property features: Move‑in ready medical suites; Ample on‑site parking for staff and patients; Near Nationwide Children’s Hospital Main Campus and OhioHealth Grant Medical Center
    More about this property
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