Prominent historic retail building in downtown Panama City for lease.
Space Size2,500 SF - 12,700 SF
Lot Size0.19 Acres
Days on Market415
Property Features for 485 Harrison Ave
General Information
Standard statusActive
Size2,500 SF - 12,700 SF
Lot size0.19 Acres
Property subtypeRETAIL
Spaces For Lease
at 485 Harrison AveContact us
485 Harrison AveAVAILABLE, Now
Floor1
Size2,500 SF
TypeRETAIL
RateContact for pricing
Lease TypeNNN
SubleaseNo
- 485 Harrison Avenue offers a rare opportunity to lease a prominent historic retail building in the heart of downtown Panama City. This two-story, ±12,700 SF building is situated on a high-visibility corner at Harrison Avenue and 5th Street, steps from government offices, banks, restaurants, and waterfront amenities. With vintage charm, expansive storefront windows, and flexible configurations, this former drugstore has long served as a landmark in the community. Space Options Being Considered: 1. Full Building – ±12,700 SF (Two Floors) Ideal for a flagship retail or mixed-use concept Includes ±8,608 SF on the ground floor and ±4,098 SF upstairs Prominent corner signage and dual street frontage Access to both floors via internal staircase 2. Ground Floor Only – ±8,608 SF High ceilings, open retail floorplate, and natural light Excellent for retail showroom, food/beverage, or gallery use 3. Multi-Tenant Ground Floor Concept – ±2,500 to ±2,600 SF Suites Proposed three-suite / multi-tenant layout with units sizes ranging of approximately 2,500, 5,000 to 6,000 +/- SF combinations Each space has direct exterior access and storefront exposure Ideal for boutique shops, local service providers, or small food/beverage operators *Pricing & timeline to be determined if multi-tenant options are pursued Location Description Positioned at the corner of Harrison Avenue and 5th Street, this building benefits from excellent foot traffic, visibility, and proximity to key downtown attractions. Located just four blocks from the marina and within walking distance of downtown's revitalized shops and businesses, 485 Harrison Avenue anchors Historic Downtown Panama City's main street. Highlights Iconic Downtown Corner: Prime visibility at Harrison Avenue & 5th Street Flexible Floorplans: Options for full-building, single-floor, or multi-tenant use Historic Character: Formerly the downtown corner drugstore with postcard-worthy prominence Large Storefront Windows: Expansive glass line ideal for display and branding Walkable Location: Surrounded by restaurants, government offices, and waterfront
Contact us
485 Harrison Ave$15/SF/Yr
FloorBldg
Size12,700 SF
TypeRETAIL
Lease TypeNNN
AvailabilityAVAILABLE, Now
SubleaseNo
- 485 Harrison Avenue offers a rare opportunity to lease a prominent historic retail building in the heart of downtown Panama City. This two-story, ±12,700 SF building is situated on a high-visibility corner at Harrison Avenue and 5th Street, steps from government offices, banks, restaurants, and waterfront amenities. With vintage charm, expansive storefront windows, and flexible configurations, this former drugstore has long served as a landmark in the community. Space Options Being Considered: 1. Full Building – ±12,700 SF (Two Floors) Ideal for a flagship retail or mixed-use concept Includes ±8,608 SF on the ground floor and ±4,098 SF upstairs Prominent corner signage and dual street frontage Access to both floors via internal staircase 2. Ground Floor Only – ±8,608 SF High ceilings, open retail floorplate, and natural light Excellent for retail showroom, food/beverage, or gallery use 3. Multi-Tenant Ground Floor Concept – ±2,500 to ±2,600 SF Suites Proposed three-suite / multi-tenant layout with units sizes ranging of approximately 2,500, 5,000 to 6,000 +/- SF combinations Each space has direct exterior access and storefront exposure Ideal for boutique shops, local service providers, or small food/beverage operators *Pricing & timeline to be determined if multi-tenant options are pursued Location Description Positioned at the corner of Harrison Avenue and 5th Street, this building benefits from excellent foot traffic, visibility, and proximity to key downtown attractions. Located just four blocks from the marina and within walking distance of downtown's revitalized shops and businesses, 485 Harrison Avenue anchors Historic Downtown Panama City's main street. Highlights Iconic Downtown Corner: Prime visibility at Harrison Avenue & 5th Street Flexible Floorplans: Options for full-building, single-floor, or multi-tenant use Historic Character: Formerly the downtown corner drugstore with postcard-worthy prominence Large Storefront Windows: Expansive glass line ideal for display and branding Walkable Location: Surrounded by restaurants, government offices, and waterfront
Contact us
Listing Agency:Five Bridges Real Estate Services(850) 913-9133
Added: Aug 26, 2025Changed: Aug 8Last Checked: Jul 25 at 7:53AM
Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of Five Bridges Real Estate Services
Investment Insights
Based on property information with market context.
Located at the corner of Harrison Avenue and 5th Street in downtown Panama City, the property at 485 Harrison Avenue offers a leasing opportunity in a historic retail building. The two-story building has a total area of approximately 12,700 square feet. The building is located steps from government offices, banks, restaurants, and waterfront amenities. The former drugstore has vintage charm, expansive storefront windows, and flexible configurations. Space options being considered include: the full building with approximately 12,700 square feet, including approximately 8,608 square feet on the ground floor and approximately 4,098 square feet upstairs, the ground floor only with approximately 8,608 square feet, or a multi-tenant ground floor concept with suites ranging from approximately 2,500 to approximately 6,000 square feet. The full building option is suited for a flagship retail or mixed-use concept. The ground floor features high ceilings, an open retail floorplate, and natural light, making it suitable for a retail showroom, food or beverage establishment, or gallery. The multi-tenant ground floor concept proposes a three-suite layout, each with direct exterior access and storefront exposure, ideal for boutique shops, local service providers, or small food and beverage operators. The building benefits from foot traffic, visibility, and proximity to downtown attractions, located four blocks from the marina and within walking distance of shops and businesses. It anchors Historic Downtown Panama City's main street.
Key Highlights
Prime corner location at Harrison Avenue & 5th Street in Historic Downtown Panama City.
Flexible floorplan options: full building, single floor, or multi‑tenant suites.
High visibility with large storefront windows ideal for display and branding.
Property Analytics
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Current Use
Harris Business Machines, ...Computer & Electronic Repair
Suggested Use
Top PickBakeryGarden Center(Bike/Boat/Book/etc) StoreCafe & Coffee ShopLocksmithGym & Fitness Center
Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.
Retail space - Prominent historic retail building in downtown Panama City for lease.
Where is this retail space located?
The property is located at 485 Harrison Ave Panama City, FL.
What is the lease rate?
The lease rate is $15 SF/Yr.
What are key features of this property?
This property features: Prime corner location at Harrison Avenue & 5th Street in Historic Downtown Panama City.; Flexible floorplan options: full building, single floor, or multi‑tenant suites.; High visibility with large storefront windows ideal for display and branding.
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