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Mixed-Use Property with Medical Layout
For Sale
Contact for pricing
Pending

4221 Derry Street, Harrisburg, PA 17111

Corner-lot building combines an established medical configuration with a second-floor apartment and Commercial Limited zoning.

Property SizeContact for details
Days on Market146

Property Features for 4221 Derry Street

General Information

Standard status Pending
Property subtype Mixed Use

Additional Details

Multifamily Units 1

Building Details

Buildings 1
Tenancy Multi
Listing Agency: NAI CIR
Listed By: Amber Corbo · License #PA
Source: Crexi
Added: Apr 12 Changed: Aug 31 Last Checked: Sep 4 at 7:39AM

Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of NAI CIR

Investment Insights

Based on property information with market context.

This mixed-use building includes a medical office configuration on the main level and an apartment on the second floor. The residential component produces income, while the commercial space has supported the same tenant for 5 years. Recent capital improvements include a new roof, A/C unit, and hot water heater.

Commercial Limited zoning allows a broad range of uses. The existing medical arrangement can be retained, adapted for a similar application requiring plumbing in each room, or converted to conventional office space. Positioned on a corner lot along Derry Street, the property combines commercial and residential components within one building.

Key Highlights

  • Mixed‑use building with medical office configuration and second‑floor apartment
  • Income‑producing apartment located on the second floor
  • Current tenant has occupied the property for 5 years

Property Analytics

Current Use

CIC Insurance Agency Insurance Agency Penn Dot and Notary Law Firm Mary's Grooming Boutique Pet Grooming Service

Suggested Use

Top Pick Dental Office Skin Care Clinic Grocery & Convenience Store (Bike/Boat/Book/etc) Store Barber Shop Furniture & Home Goods

Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.

Lease Details

1
Residential units
Multi-tenant
Tenancy

Location Intelligence

Trade Area within ½ mile

475
Businesses Nearby

Demographics for 17111, PA

36,557
Population
14,880
Households
2.5
Avg Household Size
40
Median Age
33%
College-Educated
90%
High-School Grad
18.4 sq mi
ZIP Area
1,987
Density / Sq Mi
$84,314
Median Household Income
$47,256
Median Earnings
$1,309
Median Rent
$225,500
Median Home Value

Market

Vacancy Rate% for Office in Northeast region

13.1% 2019
15.4% 2020
17.6% 2021
19.1% 2022
20.2% 2023
20.9% 2024
19.9% 2025
Rey
Questions? Ask Rey
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Frequently Asked Questions

What type of property is this?
Mixed-use property - Corner-lot building combines an established medical configuration with a second-floor apartment and Commercial Limited zoning.
Where is this mixed-use property located?
The property is located at 4221 Derry Street Harrisburg, PA.
What are key features of this property?
This property features: Mixed‑use building with medical office configuration and second‑floor apartment; Income‑producing apartment located on the second floor; Current tenant has occupied the property for 5 years
(717) 395-1804 Call to check price and availability
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