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Turnkey Restaurant Space in Cortex
For Lease
Contact for pricing

4220 Duncan Ave St, Saint Louis, MO

Ready-to-operate restaurant with patios in the Cortex Innovation District.

Space Size5,263 SF - 11,391 SF
Lot Size1.76 Acres
Days on Market270

Property Features for 4220 Duncan Ave St

General Information

Standard status Active
Size 5,263 SF - 11,391 SF
Lot size 1.76 Acres
Property subtype RETAIL

Spaces For Lease

at 4220 Duncan Ave St Contact us

Suite 303

Floor
3
Size
7,707 SF
Type
OFFICE
Rate
Contact for pricing
Availability
AVAILABLE, Now
Sublease
No
4220 Duncan is an expanded venue for innovation and entrepreneurism for small and...
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Contact us

Suite 403

Floor
4
Size
11,391 SF
Type
OFFICE
Rate
Contact for pricing
Availability
AVAILABLE, Now
Sublease
No
4220 Duncan is an expanded venue for innovation and entrepreneurism for small and...
show more
Contact us

Turnkey Restaurant Space Available for Lease

Size
5,263 SF
Type
RETAIL
Rate
Contact for pricing
Lease Type
GROSS
Availability
AVAILABLE, Now
Turnkey Restaurant Space Available for Lease in the Heart of the Cortex Innovation...
show more
Contact us
Listing Agency: SmartEquity
Listed By: Brandon Smart · License #MO 1999080493
Source: Moodyscre
Added: Nov 23, 2025 Changed: Aug 16 Last Checked: Aug 20 at 7:35AM

Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of SmartEquity

Investment Insights

Based on property information with market context.

A 5,263 square-foot restaurant space is available for lease. The property is located in the heart of the Cortex Innovation District and is ready for immediate occupancy. The fully built-out restaurant includes two expansive outdoor patios totaling 2,126 square feet. The patios are suitable for high-volume dining, events, and seasonal activation. The property is suitable for restaurants, retail properties, and turnkey restaurants.

Key Highlights

  • Turnkey 5,263 SF restaurant space ready for immediate occupancy.
  • Located in the heart of the Cortex Innovation District.
  • Includes two expansive outdoor patios totaling 2,126 square feet.

Property Analytics

Current Use

Turn key restaurants

Lease Details

NNN (Triple Net)
Lease Type

Location Intelligence

Trade Area within ½ mile

5,302
Businesses Nearby
78k
Monthly Visits Nearby
Well-served
Demand for This Use

Foot Traffic Nearby

Hotels & Casinos 38% Dining 32% Groceries 16% Shops & Services 13%
McDonald's Dining
22,069 visits/mo 0.5 miles
Marriott St. Louis Grand Hotels & Casinos
13,023 visits/mo 0.1 miles
Schnucks Groceries
12,829 visits/mo 0.0 miles
Holiday Inn St. Louis - Downtown Conv Ctr Hotels & Casinos
7,878 visits/mo 0.2 miles
Hampton Inn St. Louis-Downtown at the Gateway Arch Hotels & Casinos
6,458 visits/mo 0.4 miles

Market

Vacancy Rate% for Retail in Midwest region

8% 2020
7.3% 2021
6.5% 2022
6% 2023
5.7% 2024
6.3% 2025
Rey
Questions? Ask Rey
Realmo’s AI knows this listing — price, zoning, demand, history. Ask anything.

Similar Off Market Nearby

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  • Red Zucchini PCS & Catering 1610 Olive St, St. Louis, MO 63103
  • Nirvana Catering 1610 Olive St, St. Louis, MO 63103
  • Centenary Commissary Kitchen 1610 Olive St, St. Louis, MO 63103

Frequently Asked Questions

What type of property is this?
Restaurant - Ready-to-operate restaurant with patios in the Cortex Innovation District.
Where is this restaurant located?
The property is located at 4220 Duncan Ave St Saint Louis, MO.
What are key features of this property?
This property features: Turnkey 5,263 SF restaurant space ready for immediate occupancy.; Located in the heart of the Cortex Innovation District.; Includes two expansive outdoor patios totaling 2,126 square feet.
(314) 345-0533 Call to check price and availability
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