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    Seneca, SC

    Seneca, SC Commercial Real Estate for Sale

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    Two Warehouses Near Clemson
    Updated: Nov 25, 2025
    Two Warehouses Near Clemson

    306 By Pass 123, Seneca, SC

    $490,000
    9,650 sqft · 1.09 AC lot
    Two warehouse buildings totaling 9,650 SF on one acre in downtown Seneca.
    Zoned highway commercial, offering diverse commercial use opportunities (warehouse, office, supply, shipping, storage).
    Building C: Concrete block construction, 4,650 SF, 14’ ceiling, multiple doors (drive‑in, dock, ramped).
    Building E: Metal building, 5,000 SF, column‑free, heavy power, floor drain, 2 drive‑in doors.
    Convenient location near Clemson.
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    This listing looks promising.

    Here's a quick look at some key insights for

    306 By Pass 123, Seneca, SC

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    • Est. Cap Rate

      8.8%
      Above avg (5.9%)

    • Est. NOI

      $43K
      Annual

    • Price @ 7% Cap

      $616K
      Above asking

    • Last Sold

      Sep 2020
      $120K

    • Property Type

      Mini-Warehouse, Storage
      Built 1960
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    Seneca Commercial Building For Sale
    Updated: Jan 7
    Seneca Commercial Building For Sale

    518 W N 1st Street, Seneca, SC 29678

    $1,695,000
    8,000 sqft · 1.01 AC lot
    High‑traffic location in a growing area of Seneca, SC.
    All brick/concrete building construction.
    Existing tenants occupy approximately 8000 sqft, providing immediate income.
    Over 7000 sqft available for new tenant or owner‑occupancy.
    Warehouse‑style construction with 16‑foot ceilings.
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    Two-Lot Live-Work Development Land
    Two-Lot Live-Work Development Land

    Tract 18/19 S Walnut Street, Seneca, SC 29678

    $265,000
    2.20 AC lot

    Two adjacent lots offer flexible options for a residential build paired with a commercial storefront.

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    Versatile Retail and Office Building
    Versatile Retail and Office Building

    615 W N 1st Street, Seneca, SC 29678

    $214,900
    0.23 AC lot

    Open floor plan with two bathrooms, plus a side storage building and newly installed HVAC.

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    Seneca Retail Building For Sale
    Seneca Retail Building For Sale

    12020 North Radio Station Road, Seneca, SC 29678

    $1,399,999
    12,000 sqft · 2.42 AC lot

    12,000 SF building with conversion potential in Seneca, SC.

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    Turn-Key Restaurant Franchise Opportunity
    Turn-Key Restaurant Franchise Opportunity

    1053 By Pass 123 Bypass, Seneca, SC 29678

    $1,900,000
    0.78 AC lot

    Turn-key national franchise restaurant with real estate for sale.

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    Unrestricted Waterfront Development Land
    Unrestricted Waterfront Development Land

    Seneca Springs Landing, Seneca, SC 29678

    $425,000
    7.00 AC lot

    Unrestricted tract with 18 platted lots near Lake Hartwell, including a dock platform and prior livestock infrastructure.

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    NNN Bank Building
    NNN Bank Building

    1313 Sandifer Boulevard, Seneca, SC 29678

    $2,049,000

    For sale NNN bank building with corporate ABS structure in Seneca, SC.

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    Commercial Building with Open Plan
    Commercial Building with Open Plan

    615 W North 1st St, Seneca, SC 29678

    $214,900

    Own a tenant-occupied commercial building with an open floor plan, two bathrooms, and a recently installed HVAC unit.

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    Commercial Lot Near Wells Highway
    Commercial Lot Near Wells Highway

    Corner of Wells Hwy. & Return Church Rd. Highway, Seneca, SC 29678

    $395,000
    0.99 AC lot

    0.99-acre commercial lot with high visibility and easy access.

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    Office Building with Road Frontage
    Office Building with Road Frontage

    11081 N Radio Station Road, Seneca, SC 29678

    $217,000
    0.63 AC lot

    Single-building office asset just outside Seneca city limits with substantial road frontage on Radio Station Road.

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    Brick Concrete Warehouse Flex Building
    Brick Concrete Warehouse Flex Building

    518 W North 1st St, Seneca, SC 29678

    $1,695,000

    All-brick warehouse flex space with 16-foot ceilings and existing tenants, offering room for another tenant or owner-occupancy.

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    Freestanding Office Building
    Freestanding Office Building

    631 By Pass 123, Seneca, SC 29678

    Contact for pricing

    For sale office building at 631 By Pass 123, offering a straightforward setup for professional tenants.

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    Prime Commercial Acreage For Sale
    Prime Commercial Acreage For Sale

    1018 E. North 1st Street, Seneca, SC 29678

    $3,500,000
    4.33 AC lot

    4.3 acres in Seneca, SC, ideal for retail or hospitality.

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    The Clemson Commercial Lot
    The Clemson Commercial Lot

    189 Seneca Creek Road, Seneca, SC 29678

    $175,000
    84,942 sqft · 1.95 AC lot

    1.95 Acres Land, The Clemson Commercial Lot

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    Oconee County Land For Sale
    Oconee County Land For Sale

    8006 Keowee School Road, Seneca, SC 29672

    $619,943
    24.70 AC lot

    24.7 acres of unrestricted land near Lake Keowee.

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    60 Acres Land 101 Friendship Road Tract B
    60 Acres Land 101 Friendship Road Tract B

    101 Friendship Road, Seneca, SC 29678

    $1,000,000
    2,613,600 sqft · 60.00 AC lot

    A convenient 60 acres to everything Clemson

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    Commercial Land Near Highway 123
    Commercial Land Near Highway 123

    1.8 Acres Rochester Highway, Seneca, SC 29672

    $699,000
    1.80 AC lot

    Unrestricted 1.8-acre commercial land near major retailers and highways.

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    Commercial Land on Clemson Boulevard
    Commercial Land on Clemson Boulevard

    10149 & 10161 Clemson Blvd, Seneca, SC 29678

    $1,400,000
    3.94 AC lot

    3.94 acres of commercial land with road frontage.

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    Corner Lot in Seneca
    Corner Lot in Seneca

    911 E. North 1st Street Street, Seneca, SC 29678

    $325,000
    1.29 AC lot

    1.29 acre corner lot zoned for commercial use.

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    Commercial Land on Radio Station Road
    Commercial Land on Radio Station Road

    11081 N Radio Station Road, Seneca, SC 29678

    $250,000
    0.63 AC lot

    Commercial land with building on busy Radio Station Road.

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    Automotive Shop Near Lake Keowee
    Automotive Shop Near Lake Keowee

    445 By Pass 123, Seneca, SC 29678

    $900,000

    10-bay automotive shop, redevelopment potential for fast food.

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    Established Hibachi Restaurant for Sale
    Established Hibachi Restaurant for Sale

    1510 Blue Ridge Boulevard, Seneca, SC 29672

    $219,000

    Turnkey Hibachi restaurant with existing lease and equipment included.

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    Land Near Clemson University
    Land Near Clemson University

    Union Station Dr, Seneca, SC 29678

    $350,000
    6.54 AC lot

    Land available near Clemson University, close to lakes.

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    Seneca, SC Commercial Real Estate Market Trends and Statistics

    Explore 72 commercial real estate for sale in Seneca, SC, showcased through 28 active listings on our real estate platform. These investment opportunities span a total of 2,742,592 square feet of properties for sale, with an estimated market value of $6,758,998.

    Sale prices for business properties in Seneca, SC start at $175,000, averaging $965,571, and reaching up to $1,695,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Demographics Overview

    Population 36K
    Population Growth (5Y) +2.7%
    Median Household Income $62,735
    College Educated 31.9%

    High-Yield Neighborhoods for Investment

    Identify Seneca submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    29672 $559.2K
    29678 $1.3M

    Listings Trend

    New vs delisted commercial listings in Oconee County

    New Delisted

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    Most Searched ZIP Codes in Seneca, SC

    • 29678
    • 29672

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