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Life Science Project with Bay Views
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409-499 Illinois Street, San Francisco, CA 94158

484,000 SF life science project near Chase Center.

Space Size1,324 SF - 7,011 SF
Days on Market327
Rey
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Property Features for 409-499 Illinois Street

General Information

Standard status Active
Size 1,324 SF - 7,011 SF
Property subtype Retail

Spaces For Lease

at 409-499 Illinois Street Contact us

409 Illinois Available

Size 1,324 SF
Type Retail
• Approximately 1,324 SF rentable (1,156 SF usable) • Directly across the street from Chase Center • Highly visible location on the corner of Illinois Street and 16th Street • Second generation café space with existing kitchen infrastructure and ADA restroom • Space can be delivered with all furniture, fixtures, and equipment
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499 Illinois Available

Size 7,011 SF
Type Retail
• Approximately 7,011 SF rentable (6,374 SF usable) o Usable: Front of house: 4,700 SF o Back of house: 1,674 SF o Total usable: 6,374 SF • Rentable: o Front of house: 5,170 SF o Back of house: 1,841 SF o Total usable: 7,011 SF • Second-generation full-service restaurant space with existing kitchen infrastructure • Two full-service kitchens with venting – Front of house open kitchen and back of house prep kitchen • Type 1 & Type 2 venting • ADA restrooms • Expansive dedicated outdoor patio and garden with views of the San Francisco Bay and Chase Center • Open floorplan with direct access to office lobby • Potential for large private events • Space can be delivered with all furniture, fixtures, and equipment
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Listing Agency: CBRE | San Francisco
Listed By: Alex Sagues · License #02055525
Source: Cbre
Added: Nov 22, 2025 Changed: Oct 6 Last Checked: Oct 14 at 9:37PM

Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of CBRE | San Francisco

Investment Insights

Based on property information with market context.

The Alexandria Center for Science and Technology is a 484,000 square foot life science project featuring bay views, a large garden terrace, onsite parking, and 24/7 security. The property is situated on the San Francisco Bay waterfront, opposite Chase Center, home of the Golden State Warriors, which hosts nearly 200 events a year. It is positioned directly across the street from UCSF’s Mission Bay campus, a 3.4 million square foot research, teaching, and clinical care campus with a daytime population of nearly 15,000. The neighborhood is accessible to employees and visitors throughout the San Francisco Bay Area via Interstate 280, MUNI’s T Third Street line, Caltrain, and the future Mission Bay Ferry Landing.

Key Highlights

  • Prime location on the San Francisco Bay waterfront, opposite Chase Center.
  • Directly across from UCSF’s Mission Bay campus.
  • 484,000 square foot life science project.

Property Analytics

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Open Analytics

Current Use

Retail space

Suggested Use

Top Pick Auto Parts Store Dental Office HVAC Service Pharmacy Auto Repair Shop Grocery & Convenience Store

Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.

Lease Details

NNN (Triple Net)
Lease Type

Location Intelligence

Trade Area within ½ mile

5,500
Businesses Nearby
31k
Monthly Visits Nearby

Foot Traffic Nearby

Home Improvements & Furnishings 55% Shops & Services 22% Dining 22%
RH (Restoration Hardware) Home Improvements & Furnishings
16,096 visits/mo 0.4 miles
Shell Shops & Services
5,177 visits/mo 0.1 miles
Boba Guys Dining
4,490 visits/mo 0.5 miles
Blue Bottle Coffee Dining
2,311 visits/mo 0.3 miles
The UPS Store Shops & Services
1,658 visits/mo 0.4 miles

Demographics for 94158, CA

11,327
Population
5,300
Households
2.1
Avg Household Size
33
Median Age
77%
College-Educated
94%
High-School Grad
0.6 sq mi
ZIP Area
18,878
Density / Sq Mi
$184,294
Median Household Income
$120,408
Median Earnings
$3,316
Median Rent
$1,501,100
Median Home Value
Check the figures for this property Cap Rate, Value Estimation, Potential NOI and more
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Market

Lease Benchmarks for San Francisco, CA

$35.48 /SF/Yr
Avg Asking Price
$1.48–$85 /SF/Yr
Price Range
8,911 SF
Avg Space Size

Vacancy Rate% for Retail in San Francisco, CA

4.8% 2019
6.5% 2020
6.6% 2021
6.3% 2022
6.4% 2023
6.5% 2024
5.8% 2025

Frequently Asked Questions

What type of property is this?
Retail space - 484,000 SF life science project near Chase Center.
Where is this retail space located?
The property is located at 409-499 Illinois Street San Francisco, CA.
What are key features of this property?
This property features: Prime location on the San Francisco Bay waterfront, opposite Chase Center.; Directly across from UCSF’s Mission Bay campus.; 484,000 square foot life science project.
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