408 Greene St, Key West, FL 33040

Building Details

Year Built

1933

Spaces For Lease

at 408 Greene St Contact us

Listing office Berkshire Hathaway HomeServices Knight & Gardner Realty

Listing date Jun 11, 2026

Source Crexi

Displayed information is deemed reliable but is not guaranteed and should be independently verified.

All listing content including descriptions, pricing, images are the copyrighted material of Berkshire Hathaway HomeServices Knight & Gardner Realty

Report an issue

---

Overview

This leasing opportunity includes approximately 1,398 square feet of total space, with 1,078 square feet of ground-floor commercial area plus an additional 320-square-foot loft/workspace. The configuration supports a mix of retail and office-style operations, including gallery or service-oriented uses, depending on how you plan to use the interior and the upper workspace.

The property is located in the heart of Old Town Key West and offers usable outdoor areas at the front, side, and rear of the premises. The large backyard can support business uses such as outdoor seating, storage, product or display space, or other complementary activity. The offering is described as having excellent visibility and accessibility.

For tenants looking for adaptable space, the combination of a street-facing ground-floor area, an added loft/workspace, and multiple outdoor zones can be useful for operations that benefit from both interior customer flow and optional exterior use. The lease structure is base rent only, with NNN expenses not included, so tenants should plan for additional operating cost responsibilities separately.

Suggested Use

Law Firm Real Estate Agency Dental Office Spa & Massage Center Hair Salon Restaurant Nail Salon Building Supply Gym & Fitness Center Daycare Center

Zoning and permitted uses should be independently verified with local authorities.

Location Insight

• Map
• Local Demand

City

Key West

County

Monroe

State

Florida

Longitude

-81.8058461

Latitude

24.5584136

Nearby Similar for Lease

• 

  $8,900/Mo

  900 SF

  Retail Storefront in Cruise District

  Street-facing retail space positioned in Key West’s Old Town cruise-ship area with rear employee parking.

  419 Duval Street, Key West, FL 33040

  View Details
• 

  $26,276 SF/Yr

  7,007 SF

  Key West Office/Medical Space

  7,007 SF office/medical space in desirable New Town location.

  1111 12th Street, Key West, FL 33040

  View Details
• 

  $35,000 SF/Yr

  6,230 SF

  Prime Duval Street Commercial Building

  Two-story building on Duval Street, ideal for retail or restaurant.

  132 Duval Street, Key West, FL 33040

  View Details
• 

  $4,635/Mo

  1,235 SF

  Key West Office/Medical Space

  Move-in ready office or medical suite in central Key West.

  1111 12th Street, Key West, FL 33040

  View Details
• 

  $4,500/Mo

  1,100 SF

  End Unit Retail Space with Parking

  Centrally located Old Town end unit retail suite with hurricane-rated openings and one assigned parking spot.

  1206 White Street, Key West, FL 33040

  View Details
• 

  $8,000/Mo

  1,913 SF

  High-Visibility Retail Space on Highway

  Prime commercial property on Overseas Highway with high visibility.

  5300 Overseas Highway, Key West, FL 33040

  View Details
• 

  $1,100/Mo

  190 SF

  Key West Office Space Available

  190 sq ft office space for rent in Key West.

  3706 N Roosevelt Boulevard, Key West, FL 33040

  View Details
• 

  $6,000/Mo

  1,491 SF

  New Retail Space in Key West

  New retail space for lease in a mixed-use development.

  3201 Flagler Avenue, Key West, FL 33040

  View Details
• 

  $1,400/Mo

  160 SF

  Updated Office Space in Key West

  Small, updated office space in Old Town Key West.

  524 Eaton Street, Key West, FL 33040

  View Details
• 

  $5,828/Mo

  657 SF

  Key West Retail Space For Rent

  Retail space in high-traffic Key West location.

  431 Front Street, Key West, FL 33040

  View Details
• 

  $44,677 SF/Yr

  5,901 SF

  Duval Street Retail Opportunity

  Prime retail or restaurant space on Key West's Duval Street.

  210-216 Duval Street, Key West, FL 33040

  View Details
• 

  $1,250/Mo

  232 SF

  Updated Office Space in Key West

  Small, updated office space in Old Town Key West.

  524 Eaton Street, Key West, FL 33040

  View Details

FAQs

What type of property is this?

Retail space - Flexible ground-floor retail or office layout with a loft/workspace and usable front, side, and rear outdoor areas.

Where is this retail space located?

The property is located at 408 Greene St Key West, FL.

What are key features of this property?

This property features: Year built 1933 building with approx. 1,398 SF total space: 1,078 SF ground‑floor plus a 320 SF loft/workspace; Flexible layout suitable for retail, office, gallery, or service‑oriented uses; Usable front, side, and rear outdoor areas, including a large backyard for outdoor seating, storage, displays, or events