388 Cambridge Avenue Palo Alto, CA 94306

Spaces For Lease

at 388 Cambridge Avenue Contact us

Listing office CBRE | San Francisco a***@cbre.com Show Phone

Listing date Nov 22, 2025

Source Cbre

Displayed information is deemed reliable but is not guaranteed and should be independently verified.

All listing content including descriptions, pricing, images are the copyrighted material of CBRE | San Francisco

Report an issue

---

Investment Insights

Based on property information with market context.

This premier mixed-use development at 388 Cambridge Ave. features 30,000 square feet of space, including two floors of Class A office space above two ground-floor retail spaces. The property's design incorporates a classic brick and metal facade, complemented by bronzed gold signage and fixtures. The building aims to achieve LEED Platinum certification and net-zero energy usage. Located one block from the California Street shopping and dining area, the property benefits from high foot traffic and convenient access to local amenities. Ample parking and proximity to public transportation enhance accessibility for both customers and staff. This location is suitable for retailers seeking to engage with Palo Alto’s dynamic retail environment.

Key Highlights

• Premier mixed‑use development with Class A office and retail spaces.
• Located one block from the California Avenue shopping and dining corridor.
• Sustainable design targeting LEED Platinum and net‑zero energy certification.

Property Analytics

Property Profile Location Intelligence

Similar For Rent Nearby

• 

  $5.50 SF/Yr

  10,517 SF

  Plug-and-Play Office Suite

  Modern technology-style upgrades with renovated lobby and restrooms, plus an outdoor area suited for meetings and events.

  3300 Hillview Ave, Palo Alto, CA 94304

  View Details
• 

  $43,601 SF/Yr

  Multi-Use Office and Retail Suite

  Flexible suite with two restrooms, five offices, and a large main area for office, retail, or restaurant concepts.

  353 University AVE, PALO ALTO, CA 94301

  View Details
• 

  $7,380/Mo

  3,261 SF

  Corner Retail NNN Space

  Lease a 1,200 SF corner retail/service space with C2S zoning on a Colorado Ave frontage.

  706 Colorado Ave, Palo Alto, CA 94303

  View Details
• 

  $6.45 SF/Yr

  5,387 SF

  Plug-and-Play Office Suite

  Move-in ready office with 27 workstations, three conference rooms, and a kitchenette for collaborative teams.

  385 Forest Ave, Palo Alto, CA 94301

  View Details
• 

  $87 SF/Yr

  7,400 SF

  Downtown Palo Alto Freestanding Office

  Freestanding office building in prime downtown location for sublease.

  411 High Street, Palo Alto, CA 94301

  View Details
• 

  $3.25 SF/Yr

  1,584 SF

  Downtown Palo Alto Office Space

  Office space for lease in the heart of Palo Alto.

  540 University Ave, Palo Alto, CA

  View Details
• 

  $43,601 SF/Yr

  6,014 SF

  Downtown Mixed-Use Retail Office Space

  Versatile downtown suite with multiple offices, large open area, and two restrooms for office, retail, or restaurant users.

  353 University Avenue, PALO ALTO, CA 94301

  View Details
• 

  $66 SF/Yr

  1,764 SF

  Retail Space in Palo Alto

  Prime retail space in a vibrant Palo Alto shopping center.

  833-855 El Camino Real, Palo Alto, CA

  View Details
• 

  $6.50 SF/Yr

  4,174 SF

  Palo Alto Office Sublease Available

  Sublease office space with workstations and parking near Caltrain.

  101 University Avenue, Palo Alto, CA, 94301

  View Details
• 

  $11.50 SF/Yr

  1,780 SF

  Downtown Palo Alto Office Space

  Economical Palo Alto office with flexible terms and abundant light.

  525 University Ave, Palo Alto, CA

  View Details
• 

  $7.50 SF/Yr

  988 SF

  Renovated Office Space in Palo Alto

  Available office space in a completely renovated Palo Alto building.

  535-555 Middlefield Rd, Palo Alto, CA

  View Details
• 

  $6 SF/Yr

  2,100 SF

  Freestanding Office/Tech/Medical Space Available

  2,100 SF office/tech/medical space with parking near El Camino.

  450 Sheridan Ave, Palo Alto, CA 94306

  View Details

FAQs

What type of property is this?

Retail space - Premier retail and office space in vibrant Palo Alto location.

Where is this retail space located?

The property is located at 388 Cambridge Avenue Palo Alto, CA.

What are key features of this property?

This property features: Premier mixed‑use development with Class A office and retail spaces.; Located one block from the California Avenue shopping and dining corridor.; Sustainable design targeting LEED Platinum and net‑zero energy certification.