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Class A Life Science Facility
For Lease
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330 Yale Avenue North, Seattle, WA 98109

South Lake Union Class A life science facility for lease.

Space SizeContact for details
Days on Market268

Property Features for 330 Yale Avenue North

General Information

Standard status Active
Property subtype LifeSciences
Listing Agency: CBRE - Seattle
Listed By: Paul Carr · License #104966
Source: Cbre
Added: Nov 22, 2025 Changed: Aug 8 Last Checked: May 19 at 8:43PM

Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of CBRE - Seattle

Investment Insights

Based on property information with market context.

This Class A life science facility in South Lake Union offers prominent signage opportunities facing I-5, which sees 180,000 cars per day. Lab spec suites are available on floors 2 and 3, with additional suites planned for floor 9. The property features a robust loading dock with direct access to a freight elevator and a dedicated tenant backup power generator. The building is shell and core LEED Platinum certified. Ideal life science floorplates range from 8,500 to 32,000 square feet. A common glasswash/autoclave is available, along with on-site building security, bike storage, and showers. A rooftop terrace offers views of Lake Union. The property provides easy access to SCRI, Fred Hutch, UW Medicine, and I-5. Secure tenant and visitor parking is available. On-site retail and abundant nearby restaurants enhance the location.

Key Highlights

  • Prominent signage opportunity facing I‑5’s 180,000 cars per day
  • Class A life science facility in South Lake Union
  • Lab spec suites on Floor 2 & 3, planned for Floor 9

Property Analytics

Current Use

Cascadian at 330 Yale Corporate Office

Suggested Use

Top Pick (Bike/Boat/Book/etc) Store Pet Grooming Service Pet Store Clothing & Fashion Store Butcher Electrical Service

Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.

Lease Details

NNN (Triple Net)
Lease Type

Location Intelligence

Trade Area within ½ mile

7,802
Businesses Nearby

Demographics for 98109, WA

34,551
Population
23,162
Households
1.5
Avg Household Size
32
Median Age
78%
College-Educated
98%
High-School Grad
1.9 sq mi
ZIP Area
18,185
Density / Sq Mi
$130,845
Median Household Income
$104,202
Median Earnings
$2,329
Median Rent
$986,000
Median Home Value

Market

Lease Benchmarks for Seattle, WA

$28.39 /SF/Yr
Avg Asking Price
$4.18–$53 /SF/Yr
Price Range
12,157 SF
Avg Space Size

Vacancy Rate% for Office in Seattle, WA

8.5% 2019
13.4% 2020
17.6% 2021
19.5% 2022
24.3% 2023
30% 2024
32.3% 2025
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Frequently Asked Questions

What type of property is this?
Office units - South Lake Union Class A life science facility for lease.
Where is this office units located?
The property is located at 330 Yale Avenue North Seattle, WA.
What are key features of this property?
This property features: Prominent signage opportunity facing I‑5’s 180,000 cars per day; Class A life science facility in South Lake Union; Lab spec suites on Floor 2 & 3, planned for Floor 9
More about this property
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