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Class A Research Facility
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222 5th Avenue North, Seattle, WA 98109

197,919 RSF Class A life science facility for rent.

Space Size23,511 SF - 25,554 SF
Days on Market315

Property Features for 222 5th Avenue North

General Information

Standard status Active
Size 23,511 SF - 25,554 SF
Property subtype LifeSciences

Spaces For Lease

at 222 5th Avenue North Contact us

Level 3 Available

Size 23,540 SF
Type Lifesciences
Divisible down to 500 SF
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Level 4 Available

Size 23,579 SF
Type Lifesciences
Spec Suites Available North Suite: 11,222 SF South Suite: 11,902 SF
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Level 2 Available

Size 25,554 SF
Type Lifesciences
Spec Suites Available North Suite: 12,338 SF South Suite: 13,381 SF
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Level 5 Available

Size 23,599 SF
Type Lifesciences
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Level 6 Available

Size 23,629 SF
Type Lifesciences
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Level 7 Available

Size 23,599 SF
Type Lifesciences
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Level 8 Available

Size 23,511 SF
Type Lifesciences
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Level 9 Available

Size 23,754 SF
Type Lifesciences
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Listing Agency: CBRE
Listed By: Marcus Yamamoto · License #104966
Source: Cbre
Added: Nov 22, 2025 Changed: Oct 3 Last Checked: Oct 2 at 7:45PM

Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of CBRE

Investment Insights

Based on property information with market context.

This is a 197,919 RSF, 10-story Class A facility purpose-built for research. It offers central access to UW Medicine, Fred Hutch, Allen Institute, and SCRI.

Key Highlights

  • State‑of‑the‑art Class A life science facility.
  • Boasting 197,919 RSF (Rentable Square Feet).
  • Purpose‑built for research.

Property Analytics

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Open Analytics

Current Use

Office buildings

Suggested Use

Top Pick Building Supply Auto Repair Shop Auto Parts Store Big Box & Wholesale Store Electrical Service HVAC Service

Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.

Lease Details

NNN (Triple Net)
Lease Type

Location Intelligence

Trade Area within ½ mile

7,781
Businesses Nearby

Demographics for 98109, WA

34,551
Population
23,162
Households
1.5
Avg Household Size
32
Median Age
78%
College-Educated
98%
High-School Grad
1.9 sq mi
ZIP Area
18,185
Density / Sq Mi
$130,845
Median Household Income
$104,202
Median Earnings
$2,329
Median Rent
$986,000
Median Home Value
Check the figures for this property Cap Rate, Value Estimation, Potential NOI and more
View Realmo Analytics

Market

Lease Benchmarks for Seattle, WA

$33.9 /SF/Yr
Avg Asking Price
$22–$42.5 /SF/Yr
Price Range
24,518 SF
Avg Space Size

Vacancy Rate% for Office in Seattle, WA

8.5% 2019
13.4% 2020
17.6% 2021
19.5% 2022
24.3% 2023
30% 2024
32.3% 2025
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Frequently Asked Questions

What type of property is this?
Office building - 197,919 RSF Class A life science facility for rent.
Where is this office building located?
The property is located at 222 5th Avenue North Seattle, WA.
What are key features of this property?
This property features: State‑of‑the‑art Class A life science facility.; Boasting 197,919 RSF (Rentable Square Feet).; Purpose‑built for research.
More about this property
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