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Historic Brick and Beam Office
For Lease
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222 Third Street, Cambridge, MA 02142

Office space in a historic building near transit and amenities.

Space Size1,691 SF
Property Size120,668 SF
Days on Market286

Property Features for 222 Third Street

General Information

Standard status Active
Size 1,691 SF
Class B
Property subtype Office

Building Details

Building Size 120,668 SF

Spaces For Lease

at 222 Third Street Contact us

222 Third Street (Sublease)

Size
1,691 SF
Type
Office Building
Term
Negotiable
Rate
Contact for pricing
Contact us
Listing Agency: Boston Realty Advisors
Listed By: Owen Murphy · License #MA #9632849-RE-S
Source: Bradvisors
Added: Nov 24, 2025 Changed: Aug 25 Last Checked: Sep 5 at 7:02AM

Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of Boston Realty Advisors

Investment Insights

Based on property information with market context.

The American Twine Building offers office spaces within a historic brick and beam structure. Located within walking distance of the Kendall Square Red Line and Lechmere Green Line MBTA stations, the building is surrounded by new restaurants and retail options. Suites feature exposed brick and beams, complemented by large windows that provide natural light. The property provides on-site reserved parking, 24-hour security, a grab-and-go cafe, showers, and a shared conference room. The available space is 3,597 square feet.

Key Highlights

  • Convenient location near Kendall Square Red Line and Lechmere Green Line MBTA stations.
  • Historic brick and beam building with exposed brick and beams and large windows.
  • Abundance of natural light throughout suites.

Property Analytics

Current Use

Vibrant Insights Consultant Carlone & Associates Architect Zapoint Business Service Center CoLucid Pharmaceuticals, Inc Factory Intrepid (Bike/Boat/Book/etc) Store

Suggested Use

Top Pick Nail Salon Kitchen & Bath Showroom Food Market Grocery & Convenience Store Home Appliance Store Tattoo & Piercing Shop

Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.

Lease Details

NNN (Triple Net)
Lease Type

Location Intelligence

Trade Area within ½ mile

4,763
Businesses Nearby

Demographics for 02142, MA

4,499
Population
2,445
Households
1.8
Avg Household Size
32
Median Age
91%
College-Educated
100%
High-School Grad
0.3 sq mi
ZIP Area
14,997
Density / Sq Mi
$168,788
Median Household Income
$82,157
Median Earnings
$3,501
Median Rent
$1,726,900
Median Home Value

Market

Vacancy Rate% for Office in Northeast region

13.1% 2019
15.4% 2020
17.6% 2021
19.1% 2022
20.2% 2023
20.9% 2024
19.9% 2025
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Frequently Asked Questions

What type of property is this?
Office building - Office space in a historic building near transit and amenities.
Where is this office building located?
The property is located at 222 Third Street Cambridge, MA.
What are key features of this property?
This property features: Convenient location near Kendall Square Red Line and Lechmere Green Line MBTA stations.; Historic brick and beam building with exposed brick and beams and large windows.; Abundance of natural light throughout suites.
More about this property
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