141 Portland Street, Cambridge, MA 02139

Spaces For Lease

at 141 Portland Street Contact us

Listing office CBRE | Boston t***@cbre.com Show Phone

Listing date Mar 16, 2026

Source Cbre

Displayed information is deemed reliable but is not guaranteed and should be independently verified.

All listing content including descriptions, pricing, images are the copyrighted material of CBRE | Boston

Report an issue

---

Overview

Available for lease is 4,715 to 63,337 square feet of office space at 141 Portland Street in Cambridge, Massachusetts. The space is located on the lower level, floors 1-2, and floors 8-10. The building is situated across the street from Technology Square and One Kendall Square developments, providing an advantageous location for companies seeking a Kendall Square address. The property is located minutes from downtown Boston, Logan Airport, Harvard Square, and Back Bay. Access is facilitated by Interstate 93, the Red Line Kendall MBTA Station, and the EZ Ride Shuttle Bus. The surrounding neighborhood offers a variety of shops, restaurants, and cinemas. Neighboring institutions and corporations include MIT, Amgen, Biogen, and Novartis.

Suggested Use

Nail Salon Hair Salon Nursing Home Food Market Nursing Home Cosmetic Store Big Box & Wholesale Store Discount Store Kitchen & Bath Showroom Carpet & Flooring Store

Zoning and permitted uses should be independently verified with local authorities.

Location Insight

• Map
• Local Demand

City

Cambridge

County

Suffolk

State

Massachusetts

Longitude

-71.0923

Latitude

42.3656

Nearby Similar for Lease

• 

  $48 SF/Yr

  6,846 SF

  Cambridge Office Space with River Views

  Renovated office space with Charles River views and easy access.

  810 Memorial Dr, Cambridge, MA 02139

  View Details
• 

  $48 SF/Yr

  2,442 SF

  Cambridge Office Space Available

  Renovated office space with river views and convenient amenities.

  810 Memorial Dr, Cambridge, MA 02139

  View Details
• 

  $48 SF/Yr

  443 SF

  Cambridge Office Space For Lease

  Renovated office spaces with amenities near universities and public transportation.

  810 Memorial Dr, Cambridge, MA 02139

  View Details
• 

  $45 SF/Yr

  2,080 SF

  Cambridge Office Space for Rent

  Modern office space near Alewife T station with flexible layout.

  185 Alewife Brook Pkwy, Cambridge, MA 02138

  View Details
• 

  $45 SF/Yr

  1,250 SF

  Cambridge Office Suite Near Transit

  1,250 SF office suite near Central Square T.

  552 Massachusetts Ave, Cambridge, MA 02139

  View Details
• 

  $45 SF/Yr

  1,500 SF

  Office Suite Near Central Square T

  An office suite with open-plan work area, conference room, three interior offices, and shared kitchen with 24/7 access.

  552 Massachusetts Ave, Cambridge, MA 02139

  View Details
• 

  $45 SF/Yr

  2,100 SF

  Built-Out Studio Office Suite

  Like-new studio suite with wood floors and multiple offices, suitable for open-area fitness and wellness uses.

  552 Massachusetts Ave, Cambridge, MA 02139

  View Details
• 

  $39 SF/Yr

  2,239 SF

  Cambridge Office Space For Lease

  Office space with private entrance and signage opportunities in Cambridge.

  6 University Road, Cambridge, MA 02138

  View Details
• 

  $40 SF/Yr

  850 SF

  Cambridge Office Space For Rent

  Office space with on-site parking and convenient public transportation.

  545 Concord Ave, Cambridge, MA 02138

  View Details
• 

  $39 SF/Yr

  5,170 SF

  Cambridge Commercial Space For Lease

  Office space available in Cambridge, suitable for various businesses.

  2-6 University Road, Cambridge, MA 02138

  View Details
• 

  $39 SF/Yr

  2,931 SF

  Cambridge Office Space for Lease

  Office space with private entrance and signage opportunities in Cambridge.

  2 University Road, Cambridge, MA 02138

  View Details
• 

  $25 SF/Yr

  3,000 SF

  Cambridge Office Suite For Lease

  3,000 sq ft office suite near public transportation.

  26 New St, Cambridge, MA 02138

  View Details

FAQs

What type of property is this?

Office building - High-quality office space in thriving Kendall Square neighborhood.

Where is this office building located?

The property is located at 141 Portland Street Cambridge, MA.

What are key features of this property?

This property features: Prime Kendall Square Location: Directly across from Technology Square and One Kendall Square.; Excellent Transportation Access: Proximity to I‑93, Red Line (Kendall MBTA), and EZ Ride Shuttle.; High‑Quality Office Space: Available space ranges from 4,715 to 63,337 SF.