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Move-In Ready Medical Office Building
For Lease
Contact for pricing

500 E Main St, Columbus, OH 43215

Three-floor medical office with newly renovated lobby, covered patient drop-off, and ample on-site parking.

Space Size10,446 SF
Days on Market554

Property Features for 500 E Main St

General Information

Standard status Active
Size 10,446 SF
Property subtype OFFICE

Additional Details

Highway Access Yes

Amenities

Move-in ready medical suites
Walkable amenities
Newly renovated lobby
Covered patient drop-off
Ample on-site parking
Near Nationwide Children’s Hospital Main Campus and OhioHealth Grant Medical Center
In the heart of downtown with convenient highway access
Professional management and architectural space planning
Market leading TI packages

Building Details

Stories 3

Spaces For Lease

at 500 E Main St Contact us

500 E Main St

Floor
3
Size
10,446 SF
Type
OFFICE
Rate
Contact for pricing
Availability
AVAILABLE, Now
Sublease
No
- 55,844 SF - 3 floors - Move-in ready medical suites - Walkable amenities -...
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Listing Agency: JLL | Columbus
Listed By: Andy Dutcher, SIOR
Source: Moodyscre
Added: Mar 6, 2025 Changed: Sep 10 Last Checked: Sep 10 at 5:57AM

Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of JLL | Columbus

Investment Insights

Based on property information with market context.

This move-in ready medical office building offers 55,844 SF across three floors, with suites designed for medical use. The property includes a newly renovated lobby and a covered patient drop-off area, supported by professional management and architectural space planning, along with tenant improvement packages.

Located near Nationwide Children’s Hospital Main Campus and OhioHealth Grant Medical Center, the building sits in the heart of downtown with convenient highway access. Ample on-site parking is available for patient and staff convenience.

For tenants evaluating office space within a healthcare-focused setting, the building’s multi-floor configuration and healthcare-oriented improvements provide a practical foundation for occupancy.

Key Highlights

  • 55,844 SF medical office building with 3 floors
  • Move‑in ready medical suites
  • Newly renovated lobby

Property Analytics

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Current Use

Zimmer Inc Industrial Manufacturer OhioHealth Laboratory Services ... Medical Laboratory Fat Pat's BBQ Restaurant Dr. James B. ... Physician Downtown Laboratory Patient ... Medical Laboratory

Suggested Use

Top Pick Electrical Service Auto Parts Store (Bike/Boat/Book/etc) Store Grocery & Convenience Store Furniture & Home Goods Kitchen & Bath Showroom

Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.

Lease Details

Yes
Highway access
NNN (Triple Net)
Lease Type

Location Intelligence

Trade Area within ½ mile

5,960
Businesses Nearby
Under-served
Demand for This Use

Demographics for 43215, OH

20,761
Population
13,428
Households
1.5
Avg Household Size
32
Median Age
71%
College-Educated
97%
High-School Grad
5.1 sq mi
ZIP Area
4,071
Density / Sq Mi
$74,469
Median Household Income
$59,521
Median Earnings
$1,487
Median Rent
$508,300
Median Home Value
Check the figures for this property Cap Rate, Value Estimation, Potential NOI and more
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Market

Lease Benchmarks for Columbus, OH

$15.02 /SF/Yr
Avg Asking Price
$7–$33.42 /SF/Yr
Price Range
8,572 SF
Avg Space Size

Vacancy Rate% for Office in Columbus, OH

14.1% 2019
20.2% 2020
23.4% 2021
26.3% 2022
25.6% 2023
24.1% 2024
23.5% 2025
Rey
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Frequently Asked Questions

What type of property is this?
Medical Office Space - Three-floor medical office with newly renovated lobby, covered patient drop-off, and ample on-site parking.
Where is this medical office space located?
The property is located at 500 E Main St Columbus, OH.
What are key features of this property?
This property features: 55,844 SF medical office building with 3 floors; Move‑in ready medical suites; Newly renovated lobby
(614) 460-4403 Call to check price and availability
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