Freestanding Retail/Medical Space Available

222 Main St, Acton, MA 01720

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For Lease

$21 SF/Yr $5,250/Mo (calc)

Retail/medical space with high visibility and easy access.

Property size:

3,000 SF

HighLights

Superb visibility and easy accessibility.
Less than 1/4 mile from Route 2 (exit 42) and the Acton Commuter Rail (MBTA) station.
Building improvements in 2018: new roof, HVAC, exterior painting, and new sidewalk.
Approx. 3,000 +/- square feet of retail/medical space.
Suitable for medical or retail use.
Located in a plaza with Dunkin Donuts, hardware store, and restaurant.

We can help!

Listing Contact

George A. Robb

Learn more

For Lease

$21 SF/Yr $5,250/Mo (calc)

Retail/medical space with high visibility and easy access.

Property size:

3,000 SF

Added:: Apr 22, 2026
Days on Market:: 51
Last Refresh:: Apr 22 at 12:18 pm

Property Features for 222 Main St

General Information

Standard status: Active
Size: 3,000 SF

Building Details

Year Built: 1960

We can help!

Listing Contact

George A. Robb

Listing agent George A. Robb

Listing office Omni Properties

Listing date Apr 22, 2026

Source Liongatere

Displayed information is deemed reliable but is not guaranteed and should be independently verified.

All listing content including descriptions, pricing, images are the copyrighted material of Omni Properties

HighLights

Superb visibility and easy accessibility.
Less than 1/4 mile from Route 2 (exit 42) and the Acton Commuter Rail (MBTA) station.
Building improvements in 2018: new roof, HVAC, exterior painting, and new sidewalk.
Approx. 3,000 +/- square feet of retail/medical space.
Suitable for medical or retail use.
Located in a plaza with Dunkin Donuts, hardware store, and restaurant.

Overview

A freestanding building offers approximately 3,000 square feet of retail or medical space. The property benefits from high visibility and easy accessibility. It is located less than a quarter of a mile from Route 2 (exit 42) and the Acton Commuter Rail (MBTA) station. Building improvements completed in 2018 include a new roof, HVAC system, exterior painting, and a new sidewalk on the premises. The building is suitable for medical or retail use. Another tenant in the building is a pediatric dentist with a high-quality fit-up and state-of-the-art equipment. The second building in the plaza includes a Dunkin Donuts, a hardware store, and a restaurant.

Location Intelligence

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Village Pediatric Dental Dental Office Acton Fit Body ... Gym & Fitness Center Extra Steps Pediatric ... Rehabilitation Center

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Local Demand

City: Acton
County: Middlesex
State: Massachusetts
Longitude: -71.4564292
Latitude: 42.469519

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For lease
Retail space
MA
Acton
01720
222 Main St

What type of property is this?

Retail space - Retail/medical space with high visibility and easy access.

Where is this retail space located?

The property is located at 222 Main St Acton, MA.

What is the lease rate?

The lease rate is $21 SF/Yr.

What are key features of this property?

This property features: Superb visibility and easy accessibility.; Less than 1/4 mile from Route 2 (exit 42) and the Acton Commuter Rail (MBTA) station.; Building improvements in 2018: new roof, HVAC, exterior painting, and new sidewalk.