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Centennial, CO Commercial Real Estate for Lease

154 results
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The Point at Inverness
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The Point at Inverness

Discover many ways to work your way in Beau Terre

8310 Valley Hwy, Unit 300, Centennial, CO 80112
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CO, Centennial - Chester St
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CO, Centennial - Chester St

8085 Chester St, Centennial, CO 80112

Discover many ways to work your way in CO, Centennial - Chester St

  • Be part of a vibrant coworking community with dedicated desk or hot desking options in thousands of idyllic locations across the globe
  • Grow in a modern workplace with the added advantage of a benefits program offering exclusive discounts and bespoke procurement support
  • Access Regus' network of workspaces and business lounges as often as you need and take advantage of their exclusive benefits
  • Impress clients, hold memorable workshops, and deliver a winning pitch in Regus' meeting spaces, fully equipped for gatherings of any size
  • Collaborate with like‑minded professionals and enjoy regular networking and community events with a Regus membership
Updated: Feb 19
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Centennial Retail and Office Space
$21 SF/Yr
10,880 SF

Centennial Retail and Office Space

5730 E Otero Ave, Centennial, CO 80112

Office and retail spaces available in Centennial, Colorado.

  • Strategically located in Centennial, a thriving city with abundant amenities.
  • King Soopers anchored, ensuring consistent traffic.
  • Convenient access to major transportation routes, dining, shopping, and entertainment.
  • High income area, attracting a desirable customer base.
  • Multiple uses permitted, offering flexibility for various businesses.
Updated: Nov 21, 2025
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Centennial Office Space For Rent
$20 SF/Yr
13,178 SF

Centennial Office Space For Rent

Office space in a quiet, private building with ample parking.

6746 S Revere Pkwy, Bldg B, Centennial, CO 80112
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Centennial Office Space For Rent
$15 SF/Yr
9,974 SF

Centennial Office Space For Rent

Office space in park-like setting with flexible terms.

7353 South Alton Way, Building A, Centennial, CO 80112
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Updated Office Medical Building
$24 SF/Yr
29,788 SF

Updated Office Medical Building

29,755 SF office medical building with ample parking.

6979 S Holly Circle, Centennial, CO 80112
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Retail Space in Southglenn Square
Contact for pricing
61,487 SF

Retail Space in Southglenn Square

Retail spaces for lease in high-traffic Centennial shopping center.

7562 - 7592 S University Blvd, Centennial, CO 80122
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Centennial Flex Space with Storage
$20 SF/Yr
6,600 SF

Centennial Flex Space with Storage

Flex space with drive-in door and fenced outdoor storage.

15354 East Hinsdale Circle, Centennial, CO 80112
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Centennial Retail Space Available
$8 SF/Yr
8,990 SF

Centennial Retail Space Available

Retail space available for lease in Centennial, Colorado.

7562-7592 S University Blvd, Centennial, CO
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Retail Space in Heritage Green
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12,000 SF

Retail Space in Heritage Green

Retail units available in a busy Centennial shopping center.

8203-8269 South Holly Street |, Centennial, CO 80122
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Centennial Office Space For Rent
$21 SF/Yr
2,983 SF

Centennial Office Space For Rent

Office space in a quiet, private, and accessible building.

6746 S Revere Pkwy, Centennial, CO
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Centennial Office Space Available Now
$18 SF/Yr
110,718 SF

Centennial Office Space Available Now

1,938 SF office space for lease in Centennial, Colorado.

7430 E Caley Avenue #130E, Centennial, CO 80111
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Centennial Office Suite with Balcony
$3,669 /Mo
655 SF

Centennial Office Suite with Balcony

Office suite with mountain views, covered parking, and patio.

13275 E Freemont Pl, Centennial, CO
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Centennial Retail Space For Rent
$21 SF/Yr
1,676 SF

Centennial Retail Space For Rent

Retail space for lease in Centennial, Colorado.

5730 E Otero, Centennial, CO
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Class A Office Space Available
$18 SF/Yr
49,953 SF

Class A Office Space Available

Tenant-centric office space with modern amenities and flexible options.

9110 E Nichols Ave, Centennial, CO
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Office Space with Mountain Views
$24 SF/Yr
4,465 SF

Office Space with Mountain Views

Office space for rent with mountain views and rooftop access.

9200 E Mineral Ave, Centennial, CO
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Retail Space in Centennial, CO
$22 SF/Yr
7,200 SF

Retail Space in Centennial, CO

Retail space available for lease in a vibrant Littleton setting.

7680 S University Blvd, Centennial, CO
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New Centennial Flex Space
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8,000 SF

New Centennial Flex Space

Scalable, modern flex/industrial space in a premier Centennial location.

13320 E Briarwood Ave, Centennial, CO 80112
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Centennial Office Space Available
$14 SF/Yr
1,298 SF

Centennial Office Space Available

Office space available for rent in Centennial, Colorado.

7600 E Arapahoe Rd, Centennial, CO
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Retail Space in Growing Center
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2,124 SF

Retail Space in Growing Center

Retail space for lease in a high-income area.

6862-6882 S Yosemite, Centennial, CO
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Centennial Flex Space Available
$16 SF/Yr
3,524 SF

Centennial Flex Space Available

Single-story flex space complex near I-25 and Dry Creek.

7332 S Alton Way, Centennial, CO
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Centennial Flex Space Available
$12 SF/Yr
3,245 SF

Centennial Flex Space Available

Single-story flex space in Centennial, near I-25.

7310 S Alton, Centennial, CO
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Centennial Airport Office/Warehouse Complex
$12 SF/Yr
12,600 SF

Centennial Airport Office/Warehouse Complex

Single-story office/warehouse complex with convenient access to I-25.

12508-12650 E Briarwood Ave, Centennial, CO 80016
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Centennial Office Space for Rent
$17 SF/Yr
4,146 SF

Centennial Office Space for Rent

Office space featuring multiple rooms, conference room, and kitchen.

6551 S Revere Pkwy, Centennial, CO
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Centennial, CO Commercial real estate Leasing Opportunities Market Analysis

Explore Commercial real estate leasing options in Centennial, CO with 154 listings featured on our commercial real estate exchange. The current inventory includes 10,983,479,760 square feet of properties with an estimated lease value of $373 /Mo.

Estimated lease rates for Commercial real estate in Centennial, CO begin at $8 SF/Yr, with an average of $28 SF/Yr and extend to $165 SF/Yr.
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