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Prime Retail Space in Cambridge
For Lease
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181 Massachusetts Avenue, Cambridge, MA 02139

Retail space available in the Novartis research building.

Space SizeContact for details
Days on Market271

Property Features for 181 Massachusetts Avenue

General Information

Standard status Active
Property subtype Retail
Listing Agency: CBRE - Boston
Listed By: Rob Robledo · License #RES.0777085
Source: Cbre
Added: Nov 22, 2025 Changed: Jul 6 Last Checked: Aug 20 at 7:50AM

Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of CBRE - Boston

Investment Insights

Based on property information with market context.

This property offers 1,876 square feet of retail space. It is located on the street level of the 850,000 square foot Novartis Institutes for BioMedical Research building in Cambridge, Massachusetts. The property is situated across the street from the Novartis global research headquarters.

Key Highlights

  • Prime retail space in Cambridge, MA
  • Located on the street level
  • 1,876 SF of retail space

Property Analytics

Current Use

Saloniki Greek Restaurant Novartis Pharmaceuticals Factory Oath Pizza - Central ... Restaurant

Suggested Use

Top Pick Big Box & Wholesale Store Nail Salon HVAC Service Building Supply Kitchen & Bath Showroom Auto Repair Shop

Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.

Lease Details

NNN (Triple Net)
Lease Type

Location Intelligence

Trade Area within ½ mile

3,534
Businesses Nearby
30k
Monthly Visits Nearby

Foot Traffic Nearby

Dining 78% Shops & Services 22%
McDonald's Dining
16,617 visits/mo 0.3 miles
Dunkin' Donuts Dining
6,688 visits/mo 0.4 miles
Sunoco Shops & Services
4,974 visits/mo 0.1 miles
U-Haul Moving & Storage at Central Square Shops & Services
1,620 visits/mo 0.2 miles

Demographics for 02139, MA

39,525
Population
16,930
Households
2.3
Avg Household Size
30
Median Age
78%
College-Educated
94%
High-School Grad
1.6 sq mi
ZIP Area
24,703
Density / Sq Mi
$124,648
Median Household Income
$61,025
Median Earnings
$2,613
Median Rent
$1,066,200
Median Home Value

Market

Lease Benchmarks for Cambridge, MA

$53.07 /SF/Yr
Avg Asking Price
$35–$70.87 /SF/Yr
Price Range
6,329 SF
Avg Space Size

Vacancy Rate% for Retail in Northeast region

6% 2019
7.1% 2020
6.5% 2021
6% 2022
5.7% 2023
5.6% 2024
6% 2025
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Frequently Asked Questions

What type of property is this?
Retail space - Retail space available in the Novartis research building.
Where is this retail space located?
The property is located at 181 Massachusetts Avenue Cambridge, MA.
What are key features of this property?
This property features: Prime retail space in Cambridge, MA; Located on the street level; 1,876 SF of retail space
More about this property
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