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100 North Main Street, Winston-Salem, NC, 27101
Class A Office Space Available

100 North Main Street Winston-Salem, NC 27101

For Lease
Contact for pricing

Class A office tower with unparalleled amenities in Winston-Salem.

Property Size218,488 SF
Days on Market248

Property Features for 100 North Main Street

General Information

Standard status Active
Size 218,488 SF
Property subtype Office
Listing Agency:
Listed By: Richard Mossman
Source: Cbre
Added: Nov 22, 2025 Changed: Jul 6 Last Checked: Jul 27 at 6:28AM

Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of Richard Mossman

Investment Insights

Based on property information with market context.

Located at 100 N. Main Street, Wells Fargo Center in Winston-Salem is a signature office tower offering 28 floors of Class A office space. The property provides various amenities, including an on-site cafeteria, a fitness center, 24/7 security, and a barber shop. Parking is available for visitors and employees in the garage under the building, as well as in the parking deck with secure access via a walkway under Main Street. Suites are available to accommodate small tenants and large corporate users. The property is within walking distance of the Wake Forest Innovation Quarter, local restaurants, hotels, arts and entertainment venues, and the courthouse. Nearby attractions include the Winston-Salem Dash Baseball Stadium, Bailey Park, and the Kaleideum Learning Center. The property contains 218488 square feet of office space.

Key Highlights

  • Class A office space in a signature tower.
  • Unparalleled amenities: enjoy the convenience of an on‑site cafeteria, fitness center, 24/7 security, and barber shop.
  • Suites available for various tenant sizes.

Property Analytics

Property Profile Location Intelligence

Current Use

Isalis (Bike/Boat/Book/etc) Store Party City Party Supply Store Skunk Funk Big Box & Wholesale Store Carl's Trading Co Hat Shop Bushka's Kitchen LLC (Bike/Boat/Book/etc) Store

Suggested Use

Top Pick Building Supply Restaurant Big Box & Wholesale Store Auto Parts Store Auto Repair Shop HVAC Service

Zoning and permitted uses should be independently verified with authorities.

Frequently Asked Questions

What type of property is this?
Office building - Class A office tower with unparalleled amenities in Winston-Salem.
Where is this office building located?
The property is located at 100 North Main Street Winston-Salem, NC.
What are key features of this property?
This property features: Class A office space in a signature tower.; Unparalleled amenities: enjoy the convenience of an on‑site cafeteria, fitness center, 24/7 security, and barber shop.; Suites available for various tenant sizes.
More about this property
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