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Office/Life Science/R&D HQ Opportunity
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110 Worcester Street, Wellesley, MA 02481

Up to 122,730 SF opportunity in Wellesley Hills, MA.

Space Size122,730 SF
Days on Market279

Property Features for 110 Worcester Street

General Information

Standard status Active
Size 122,730 SF
Property subtype Office / Life Science / R&D

Spaces For Lease

at 110 Worcester Street Contact us

122,730 SF Full Building Availability

Size
122,730 SF
Term
Negotiable
Rate
Contact for pricing
Contact us
Listing Agency: Newmark | Boston
Listed By: Matthew Malatesta
Source: Nmrk
Added: Nov 24, 2025 Changed: Aug 23 Last Checked: Aug 29 at 8:14AM

Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of Newmark | Boston

Investment Insights

Based on property information with market context.

This property presents an opportunity for an office, life science, or R&D headquarters, offering up to 122,730 square feet of space. Located within Wellesley Gateway South, the property benefits from significant highway visibility, providing a unique opportunity for signage and branding.

Key Highlights

  • Up to 122,730 SF Office / Life Science / R&D HQ Opportunity
  • Tremendous highway visibility
  • Unique signage/branding opportunity

Property Analytics

Current Use

Flex space

Suggested Use

Top Pick Restaurant Building Supply Hair Salon Dental Office Nail Salon Big Box & Wholesale Store

Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.

Lease Details

NNN (Triple Net)
Lease Type

Location Intelligence

Trade Area within ½ mile

1,057
Businesses Nearby
Balanced
Demand for This Use

Demographics for 02481, MA

17,280
Population
5,145
Households
3.4
Avg Household Size
36
Median Age
90%
College-Educated
98%
High-School Grad
6.1 sq mi
ZIP Area
2,833
Density / Sq Mi
$250,001
Median Household Income
$82,159
Median Earnings
$3,064
Median Rent
$1,642,700
Median Home Value

Market

Vacancy Rate% for Office in Northeast region

13.1% 2019
15.4% 2020
17.6% 2021
19.1% 2022
20.2% 2023
20.9% 2024
19.9% 2025
Rey
Questions? Ask Rey
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Frequently Asked Questions

What type of property is this?
Flex space - Up to 122,730 SF opportunity in Wellesley Hills, MA.
Where is this flex space located?
The property is located at 110 Worcester Street Wellesley, MA.
What are key features of this property?
This property features: Up to 122,730 SF Office / Life Science / R&D HQ Opportunity; Tremendous highway visibility; Unique signage/branding opportunity
More about this property
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