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    Waynesville, MO Commercial Real Estate for Sale

    6 results
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    Downtown Waynesville Commercial Opportunity
    $175,000
    875 SF

    Downtown Waynesville Commercial Opportunity

    217 North St, Waynesville, MO 65583

    Versatile 875 SF commercial space with drive-through in downtown Waynesville.

    • Prime downtown Waynesville location with high visibility and foot traffic.
    • 875 sq ft of versatile commercial space suitable for various business ventures.
    • Features a highly desirable drive‑through window.
    • Option to purchase commercial freezers and other essential equipment.
    • Convenient corner location.
    Updated: Nov 29, 2025
    View details
    Historic Route 66 Landmark Property
    $399,500
    1,750 SF

    Historic Route 66 Landmark Property

    307 Historic Rte 66, Waynesville, MO 65583

    Turnkey commercial property on Historic Route 66 in Waynesville, MO.

    • Prime location on Historic Route 66 in Waynesville, offering high visibility and traffic.
    • Turnkey property previously operated as a successful coffee shop and restaurant, suitable for various businesses.
    • Ample parking, easy access, and a well‑maintained interior with a functional kitchen and spacious dining area.
    • Proximity to local attractions and Fort Leonard Wood, ensuring year‑round exposure.
    • Remodeled in 2019, blending modern updates with the nostalgic charm of Route 66.
    Updated: Nov 15, 2025
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    Turnkey Event & Hospitality Venue
    $799,000
    15.00 Acres

    Turnkey Event & Hospitality Venue

    Fully operational venue on 15 acres near Fort Leonard Wood.

    25330 Republic Rd, Waynesville, MO 65583
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    Route 66 Commercial Property
    $375,000
    2,400 SF

    Route 66 Commercial Property

    Freestanding 2,400 SF commercial building on Route 66.

    1002 Historic 66, Waynesville, MO 65583
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    Waynesville Multi-Tenant Commercial Property
    $1,400,000
    22,714 SF

    Waynesville Multi-Tenant Commercial Property

    22,714 sq ft commercial complex with 15 units.

    000 Ichord Ave, Waynesville, MO 65583
    View details
    Waynesville Office Building For Sale
    $590,000
    1.44 Acres

    Waynesville Office Building For Sale

    Commercial property with over 6,000 SF office space.

    19788 Sackett Ln, Waynesville, MO 65583
    View details
    Based on your search, we've compiled 210 Potential Opportunities for your consideration. Besides 6 Active listings in Waynesville, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 200 Off-Market properties to explore as potential leads

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Prime St. Robert Office Complex
    $395,000
    12,834 SF

    Prime St. Robert Office Complex

    Fully Leased Mixed-Use Investment

    1126 Old Route 66, Saint Robert, MO 65584
    View details
    Prime Commercial Land on Route 66
    $600,000
    5.40 Acres

    Prime Commercial Land on Route 66

    5.4 acres of highly visible land on historic Route 66.

    1125 Old Rt. 66, Saint Robert, MO 65584
    View details
    Leased Commercial Property with Warehouse
    $395,000
    0.84 Acres

    Leased Commercial Property with Warehouse

    Income-producing property with office space and warehouse, fully leased.

    1126 Old Rte 66, St Robert, MO 65584
    View details
    Prime Commercial Land Opportunity
    $849,900
    13.75 Acres

    Prime Commercial Land Opportunity

    13.75-acre commercial land with I-44 and Route 66 frontage.

    530 Old Rte 66, St Robert, MO 65584
    View details

    Explore Off-Market Properties in Waynesville, MO

    Consider similar Off-Market properties in Waynesville, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    310 Rt. 66

    310 Rt. 66

    Office space • 2,604 SF
    Value Estimation by Request
    310 Rt. 66, Waynesville, MO 65583
    View details
    1104 Rt. 66

    1104 Rt. 66

    Individual retail properties • 8,000 SF
    Value Estimation by Request
    1104 Rt. 66, Waynesville, MO 65583
    View details
    217 North St

    217 North St

    Commercial real estate • 0.06 Acres
    Value Estimation by Request
    217 North St, Waynesville, MO 65583
    View details
    24415 Highway 17

    24415 Highway 17

    Residential income properties
    Value Estimation by Request
    24415 Highway 17, Waynesville, MO 65583
    View details
    611 Us Rte

    611 Us Rte

    Commercial real estate
    Value Estimation by Request
    611 Us Rte, Waynesville, MO 65583
    View details
    309 Historic Rt. 66

    309 Historic Rt. 66

    Commercial real estate • 0.10 Acres
    Value Estimation by Request
    309 Historic Rt. 66, Waynesville, MO 65583
    View details
    1413 Rt. 66

    1413 Rt. 66

    Individual retail properties • 10,542 SF
    Value Estimation by Request
    1413 Rt. 66, Waynesville, MO 65583
    View details
    404 School St

    404 School St

    Residential income properties • 0.86 Acres
    Value Estimation by Request
    404 School St, Waynesville, MO 65583
    View details
    403 Highway 17

    403 Highway 17

    Commercial real estate • 0.19 Acres
    Value Estimation by Request
    403 Highway 17, Waynesville, MO 65583
    View details
    24610 Hwy 17

    24610 Hwy 17

    WAREHOUSE, STORAGE • 6,250 SF
    Value Estimation
    $260,000
    24610 Hwy 17, Waynesville, MO 65583-8315
    View details
    Sackett Ln

    Sackett Ln

    MINI-WAREHOUSE, STORAGE • 3,080 SF
    Value Estimation
    $300,000
    Sackett Ln, Waynesville, MO 65583
    View details
    19851 Sackett Ln, Unit A

    19851 Sackett Ln, Unit A

    MINI-WAREHOUSE, STORAGE • 3,840 SF
    Value Estimation
    $265,000
    19851 Sackett Ln, Waynesville, MO 65583-3521
    View details
    26346 Rapier Rd

    26346 Rapier Rd

    WAREHOUSE, STORAGE • 1,500 SF
    Value Estimation
    $235,000
    26346 Rapier Rd, Waynesville, MO 65583-2957
    View details
    603 Historic 66th W

    603 Historic 66th W

    MINI-WAREHOUSE, STORAGE • 3,450 SF
    Value Estimation
    $335,000
    603 Historic 66th W, Waynesville, MO 65583-2118
    View details
    16910 Lawrence Ln

    16910 Lawrence Ln

    MINI-WAREHOUSE, STORAGE • 1,264 SF
    Value Estimation
    $190,000
    16910 Lawrence Ln, Waynesville, MO 65583
    View details
    22895 Lace Ln

    22895 Lace Ln

    MINI-WAREHOUSE, STORAGE • 1,800 SF
    Value Estimation
    $235,000
    22895 Lace Ln, Waynesville, MO 65583
    View details
    22950 Hwy T T

    22950 Hwy T T

    WAREHOUSE, STORAGE • 2,878 SF
    Value Estimation
    $285,000
    22950 Hwy T T, Waynesville, MO 65583-2757
    View details
    1901 Historic 66th W

    1901 Historic 66th W

    MINI-WAREHOUSE, STORAGE • 2,400 SF
    Value Estimation
    $260,000
    1901 Historic 66th W, Waynesville, MO 65583-2419
    View details

    Waynesville, MO Commercial Real Estate Investment Opportunities Market Analysis

    Explore 185 commercial real estate investment opportunities in Waynesville, MO with 6 listings featured on our commercial real estate marketplace. The current inventory includes 30,851,762 square feet of properties with an estimated value of $43,205,200.

    Estimated prices for commercial real estate in Waynesville, MO begin at $48,500, with an average of $411,478 and extend to $9,300,000.

    In Waynesville, MO, current investment values show:

    • Retail properties positioned at $364,193
    • Individual retail properties measuring $410,400
    • Office Properties & Spaces assessed at $364,210
    • Office buildings calculated at $313,750
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    Browse Commercial real estate for Sale Near Waynesville, MO

    Popular Searches in Waynesville, MO

    Most Searched ZIP Codes in Waynesville, MO

    • 65583
    • 65556

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