Owensboro, KY Commercial real estate for sale

Versatile Commercial Building in Owensboro

$427,000

1,794 SF

Versatile Commercial Building in Owensboro

1411 E 4Th St, Owensboro, KY 42303

Free-standing commercial building suitable for various business types.

Versatile property suitable for various business types (mechanic shop, convenience store, etc.).
Environmental assessments (Phases 1 and 2) completed.
New roof planned.
Potential for remodeling into a donut shop or other desired business.
Concrete flooring.

Updated: Dec 9, 2025

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$230,000

Prime Commercial Opportunity in Owensboro, KY

501 Frederica St, Owensboro, KY 42301

High-visibility mixed-use property in downtown Owensboro, ideal for redevelopment.

Prime downtown location at the high‑traffic intersection of Frederica Street and 5th.
Unmatched exposure in a thriving commercial area.
Versatile options: renovate existing structure or redevelop the lot.
Ideal site for new construction: franchise, restaurant, retail, or local business.
Existing 3‑bay shop with office space.

Updated: Nov 12, 2025

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Renovated Downtown Owensboro Commercial Building

$4,000,000

30,600 SF

Renovated Downtown Owensboro Commercial Building

Four-story commercial building in downtown Owensboro, fully renovated with modern amenities.

121 E 2Nd St, Owensboro, KY 42303

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$290,000

Commercial Property in Owensboro, KY

Spacious commercial property suitable for retail, office, or community use.

3955 Hwy 144, Owensboro, KY 42301

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$975,000

10,500 SF

Move-in Ready Office Building

10,500 sq ft office building near bypass in Owensboro.

1650 Parrish Plaza Dr, Owensboro, KY 42301

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$595,000

5,057 SF

Historic Church Building with Amenities

Century-old church with classrooms, offices, meeting hall, and kitchen.

1400 Breckenridge St, Owensboro, KY 42303

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$622,000

Versatile Industrial Building Near Downtown

Centrally located industrial building suitable for manufacturing, warehousing, or flex.

1804 West 2Nd St, Owensboro, KY 42301

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$1,350,000

Downtown Investment Property with Multiple Streams

Turnkey bar, office space, and luxury apartment in Owensboro.

119 East 2Nd St, Owensboro, KY 42303

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Multi-Tenant Office Building in Owensboro

$799,000

17,564 SF

Multi-Tenant Office Building in Owensboro

Two-story office complex with income potential in a prime location.

1700 Frederica St, Owensboro, KY 42301

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$3,800,000

25,360 SF

Owensboro Office Investment Opportunity

High-traffic office complex with expansion potential in Owensboro, Kentucky.

3108 Fairview Dr, Owensboro, KY 42303

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$499,900

Updated Retail Building, Owensboro, KY

Recently updated retail building with tenant in Owensboro, Kentucky.

2101 W Parrish Ave, Owensboro, KY 42301

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Owensboro Retail Center Investment Opportunity

$3,600,000

11,830 SF

Owensboro Retail Center Investment Opportunity

11,830 SF retail center in a prime location.

5220 Frederica St, Owensboro, KY 42301

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$1,800,000

Turn-Key Storage Facility in Owensboro

Fully operational storage facility with climate-controlled, outdoor, and covered units.

3149 Commonwealth Ct, Owensboro, KY 42303

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$2,600,000

Income-Producing 40-Unit Apartment Complex

Fully stabilized apartment complex with consistent rent roll and strong demand.

1001 W Parrish Ave, Owensboro, KY 42301

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$99,500

Owensboro Industrial Free-Standing Building

Free-standing industrial building in Owensboro, Kentucky, available for sale.

1300 E 15Th St, Owensboro, KY 42303

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$3,999,000

Retail Center with Strong Tenants

Fully occupied shopping center with diverse tenants in growing area.

2845 W Parrish Ave, Owensboro, KY 42301

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$419,999

1,520 SF

Retail Opportunity on West Parrish

Retail property on a busy corridor with high visibility.

3196 W Parrish Ave, Owensboro, KY 42301

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$139,500

3,000 SF

Commercial Building Near 4th Street

3,000 SqFt commercial building suitable for storage or small business.

325 Hamilton Ave, Owensboro, KY 42303

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$739,000

Downtown Owensboro Mixed-Use Opportunity

Prime downtown building with retail and residential development potential.

511-513 Frederica St, Owensboro, KY 42301

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Owensboro Retail/Warehouse Space For Sale

$533,000

8,200 SF

Owensboro Retail/Warehouse Space For Sale

8200 SF shop/office/warehouse space in Owensboro, Kentucky.

2106 Triplett St, Owensboro, KY 42303

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$749,000

2,036 SF

Retail Space on Frederica Street

Retail or multi-use space available for sale or lease.

1331 Frederica St, Owensboro, KY 42301

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$299,000

Retail Building with Commercial Kitchen

Retail building with commercial kitchen, new roof, and fenced parking.

1601 W 2Nd St, Owensboro, KY 42301

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$109,900

931 SF

Owensboro Townhome with Loft

Charming townhome with downstairs bedroom and loft in Owensboro, KY.

641 Chuck Gray Ct, Owensboro, KY 42303

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$3,460,000

14,274 SF

Downtown Riverfront Office Building

Prime Owensboro Office Space, River Views

100 St Ann St, Owensboro, KY 42303

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Owensboro, KY Commercial Real Estate Investment Opportunities Market Analysis

Explore 4162 commercial real estate investment opportunities in Owensboro, KY with 91 listings featured on our commercial real estate marketplace. The current inventory includes 149,247,370 square feet of properties with an estimated value of $874,626,400.

Estimated prices for commercial real estate in Owensboro, KY begin at $35,000, with an average of $500,931 and extend to $12,550,000.

In Owensboro, KY, current investment values show:

Other commercial real estate positioned at $498,050
Land measuring $1,744,283
Other land assessed at $1,859,309
Residential income properties calculated at $2,006,375

Owensboro, KY Commercial Real Estate for Sale

Versatile Commercial Building in Owensboro

Free-standing commercial building suitable for various business types.

Prime Commercial Opportunity in Owensboro, KY

High-visibility mixed-use property in downtown Owensboro, ideal for redevelopment.