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Wayne, PA Commercial Real Estate for Lease

43 results
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Main Line Office Opportunity
$5,279 / Mo

Main Line Office Opportunity

528 E Lancaster Ave, Wayne, PA 19087

Freestanding office building with frontage on Lancaster Avenue.

  • Prominent Lancaster Avenue frontage with pylon and building signage for HIGH VISIBILITY.
  • Convenient location: short walk to Paoli‑Thorndale Train Line, Giant supermarket, and local banks.
  • Ample parking with front and rear entries for easy access.
  • Well‑equipped office space: conference room, private offices, open work area, storage, kitchenette, and two bathrooms.
  • Easy access to major highways: I‑76, I‑476, PA Turnpike, Routes 202, 422, and 3.
Updated: Feb 3
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Chesterbrook Townhome with Loft
$2,595 / Mo
1,056 SF

Chesterbrook Townhome with Loft

107 Cavalry Ct, Chesterbrook, PA 19087

Updated 2-bedroom townhome with loft in desirable Chesterbrook community.

  • Desirable Chesterbrook location with quick access to major routes.
  • Updated end‑unit townhome with 2 bedrooms, 1.5 baths, and a loft, featuring a fresh, neutral color palette.
  • Kitchen equipped with STAINLESS STEEL APPLIANCES, GRANITE countertops, white cabinetry, and subway tile backsplash.
  • Primary bedroom with VAULTED CEILINGS, private balcony, large closet, and a second‑story loft with built‑in desk and shelving.
  • Private back deck with peaceful wooded views.
Updated: Aug 7, 2025
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Wayne, PA Office Space for Lease
$8 SF/Yr
6,249 SF

Wayne, PA Office Space for Lease

Flexible Office Solutions in Chester County

724 Lancaster Ave, Wayne, PA 19087
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Wayne PA Medical Office Opportunity
Contact for pricing
14,673 SF

Wayne PA Medical Office Opportunity

Prime Medical Office Space - 7,673 SF Available

237 Lancaster Ave, Wayne, PA 19087
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Wayne, PA Medical Office Space
$20 SF/Yr
8,521 SF

Wayne, PA Medical Office Space

Prime Medical Office Suites Available

1100 Valley Rd, Wayne, PA 19087
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The Meadows Office Campus
$24 SF/Yr
32,800 SF

The Meadows Office Campus

Wayne, PA Office Space Available

0 485/487/489 Devon Park Dr, Wayne, PA 19087
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Strafford Office Space: Prime Location
$25 SF/Yr
20,000 SF

Strafford Office Space: Prime Location

Modern Office Suites Available, Chester County

85 Old Eagle School Rd, Strafford, PA 19087
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Radnor Office Space Available
$11 SF/Yr
4,629 SF

Radnor Office Space Available

Flexible workspace solutions in Radnor, PA.

201 King Of Prussia Rd, Radnor, PA 19087
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Chesterbrook Premier HQ Office Sublease
Contact for pricing
233,120 SF

Chesterbrook Premier HQ Office Sublease

Sublease opportunity in Chesterbrook, Wayne, PA, offering premier office space.

1500-1550 Liberty Ridge Dr, Wayne, PA 19087
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Wayne Flex/Industrial Space Available
Contact for pricing
61,272 SF

Wayne Flex/Industrial Space Available

61,272 SF flex/industrial space for lease in Wayne, PA.

400 Devon Park Dr, Wayne, PA 19087
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Retail Space in Wayne, PA
Contact for pricing
1,417 SF

Retail Space in Wayne, PA

Retail space available in high-traffic Wayne location.

111-295 Swedesford Rd, Wayne, PA 19087
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Premier Retail Space in Wayne
Contact for pricing
1,465 SF

Premier Retail Space in Wayne

Open-air retail destination on Lancaster Avenue in affluent Main Line.

517 Lancaster Ave, Wayne, PA 19087
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Class A Office Space Available
Contact for pricing
20,290 SF

Class A Office Space Available

40-acre campus with extensive amenities and flexible office suites.

1300 Morris Dr, Wayne, PA 19087
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Wayne Office Space Available
Contact for pricing
4,398 SF

Wayne Office Space Available

Strategically located office space with amenities and convenient access.

170 Radnor Chester Rd, Wayne, PA 19087
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Office Space Near Public Transit
$27 SF/Yr
315 SF

Office Space Near Public Transit

Office space with on-site management and ample parking.

290 King Of Prussia Rd, Wayne, PA 19087
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Premier Retail Space in Wayne
Contact for pricing
1,468 SF

Premier Retail Space in Wayne

High-end retail space in a sought-after, high-traffic location.

503 Lancaster Ave, Wayne, PA 19087
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Office Space with Mountain Views
Contact for pricing
2,602 SF

Office Space with Mountain Views

Office space in a tranquil suburban campus setting.

1200 Liberty Ridge Dr, Chesterbrook, PA 19087
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Retail Space in Devon Village
Contact for pricing
3,342 SF

Retail Space in Devon Village

Retail space available in affluent Philadelphia suburban community.

841 Lancaster Ave, Strafford, PA 19087
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Move-in Ready Office Sublease
$23 SF/Yr
2,552 SF

Move-in Ready Office Sublease

Sublease available immediately with high-end finishes through October 2026.

985 Old Eagle School Rd, Wayne, PA 19087
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Suburban Office Space with Fitness Center
Contact for pricing
41,409 SF

Suburban Office Space with Fitness Center

Office space in a tranquil suburban campus setting with amenities.

1400 Liberty Ridge Dr, Wayne, PA 19087
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Wayne Office Space Available
$26 SF/Yr
3,194 SF

Wayne Office Space Available

Office space available for lease in Wayne, Pennsylvania.

940 West Valley Rd, Wayne, PA 19087
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Radnor Office Space Available
Contact for pricing
3,936 SF

Radnor Office Space Available

Strategically located office space with amenities and transit access.

555 E Lancaster Ave, Radnor, PA 19087
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Retail Building with Drive Thru
Contact for pricing
14,673 SF

Retail Building with Drive Thru

Retail building with drive-thru available for lease.

231-245 E Lancaster Ave, Wayne, PA 19087
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Wayne Office Space Available
Contact for pricing
2,325 SF

Wayne Office Space Available

Office space available for lease in Wayne, Pennsylvania.

130 West Lancaster Ave, Wayne, PA 19087
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Wayne, PA Commercial Real Estate Leasing Opportunities Market Analysis

Explore Commercial Real Estate leasing options in Wayne, PA with 53 listings featured on our commercial real estate exchange. The current inventory includes 3,814,374,960 square feet of properties with an estimated lease value of $262 SF/Yr.

Estimated lease rates for Commercial Real Estate in Wayne, PA begin at $8 SF/Yr, with an average of $21 SF/Yr and extend to $29 SF/Yr.

In Wayne, PA, current lease rates show:

  • Office Properties & Spaces positioned at $21
  • Office space measuring $20
  • Medical offices assessed at $18
  • Healthcare properties calculated at $18
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