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    Prince Frederick, MD Commercial Real Estate for Lease

    17 results
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    Prince Frederick Office Suite For Lease
    $1,100 / Mo
    54,450 SF

    Prince Frederick Office Suite For Lease

    65 Duke St, Prince Frederick, MD 20678

    Corner office suite in a convenient Prince Frederick location.

    • Prime location in Prince Frederick's convenient office area.
    • Corner suite with large waiting area and two private offices.
    • Newly installed vinyl plank flooring and fresh paint throughout the suite.
    • Recently updated common areas including lobby and bathrooms.
    • Rent price includes monthly CAM fee.
    Updated: Nov 13, 2025
    View details
    Prince Frederick Main Level Office
    $2,400 / Mo

    Prince Frederick Main Level Office

    85 Sherry Ln, Prince Frederick, MD 20678

    Main level office space in a professional Prince Frederick building.

    • Ready for immediate occupancy with 1190 sq ft of main‑level office space.
    • Rent includes common area maintenance, water/sewer, real estate taxes, trash, and snow removal.
    • Convenient location in Prince Frederick with quick access to Route 4, courthouse, hospital, and services.
    • Features a conference room, three offices, bathroom, and kitchenette.
    • Secure access with keyed foyer entry, coded office door locks, and an exterior side entrance.
    Updated: Aug 3, 2025
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    Prince Frederick Office/Retail Space
    $1,500 / Mo

    Prince Frederick Office/Retail Space

    Office or retail space available for lease in Prince Frederick.

    101 Skipjack Rd, Prince Frederick, MD 20678
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    Small Warehouse with Office Space
    $2,000 / Mo

    Small Warehouse with Office Space

    Versatile warehouse with reception, office, and drive-in garage door.

    151 Schooner Ln #33, Prince Frederick, MD 20678
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    Built-Out Office Building For Rent
    $5,590 / Mo

    Built-Out Office Building For Rent

    Two-story office building with private offices, kitchen, and elevator.

    493 Prince Frederick Blvd, Prince Frederick, MD 20678
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    Prime Prince Frederick Retail Space
    $18 SF/Yr
    5,000 SF

    Prime Prince Frederick Retail Space

    5,000 SF Retail/Warehouse, Newly Renovated

    86B Solomons Island Rd, Prince Frederick, MD 20678
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    Calvert Village Retail Space For Lease
    Contact for pricing
    170,573 SF

    Calvert Village Retail Space For Lease

    Prime Calvert County retail space available.

    80 Dares Beach Rd, Prince Frederick, MD 20678
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    Armory Square Retail Center
    $40 SF/Yr
    8,400 SF

    Armory Square Retail Center

    New Medical/Office Retail Spaces Available

    170 Armory Rd, Prince Frederick, MD 20678
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    Main Street Medical Office Space
    $20 SF/Yr
    7,824 SF

    Main Street Medical Office Space

    Prince Frederick, MD Medical Office Suites Available

    141 Main St, Prince Frederick, MD 20678
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    Prince Frederick Medical Office Space
    Contact for pricing
    5,707 SF

    Prince Frederick Medical Office Space

    Prime Calvert County medical office suites available.

    815 Prince Frederick Blvd, Prince Frederick, MD 20678
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    Professional Building Shell Space Available
    $1,060 / Mo

    Professional Building Shell Space Available

    1,270 sq ft vacant shell space on 2nd floor.

    489 202 Main St St, Prince Frederick, MD 20678
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    Office Space on Main Street
    $1,500 / Mo

    Office Space on Main Street

    Office space for rent with frontage on Main Street.

    165 Main St, Prince Frederick, MD 20678
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    Retail Space in Prince Frederick
    Contact for pricing
    4,771 SF

    Retail Space in Prince Frederick

    Retail property available for lease in Prince Frederick, Maryland.

    120 W Dares Beach Rd, Prince Frederick, MD 20678
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    Retail Space in Prince Frederick
    Contact for pricing
    1,700 SF

    Retail Space in Prince Frederick

    Retail space available in market-dominant shopping center.

    529-559 Solomons Island Rd N, Prince Frederick, MD 20678
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    Retail Space in Prince Frederick
    Contact for pricing
    2,058 SF

    Retail Space in Prince Frederick

    Retail space available in market-dominant shopping center.

    609-865 Solomons Island Rd N, Prince Frederick, MD 20678
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    Professional Office Space Available
    $1,060 / Mo

    Professional Office Space Available

    1,270 sq ft vacant shell office space for rent.

    489 202 Main St St, Prince Frederick, MD 20678
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    Built-Out Office Space Available
    $5,590 / Mo

    Built-Out Office Space Available

    Two-story office building with private offices, kitchen, and elevator.

    493 And 201, Prince Frederick, MD 20678
    View details
    Based on your search, we've compiled 37 Potential Opportunities for your consideration. Besides 17 Active listings in Prince Frederick, MD, we suggest exploring alternatives. Similar 20 Properties for Sales.

    Explore Similar Spaces for Sale in Prince Frederick, MD

    Consider Similar Space for Sale. We found 20 Spaces in Nearby Locations matching your search parameters.

    Prince Frederick Townhome with Finished Levels
    $370,000

    Prince Frederick Townhome with Finished Levels

    Three-level townhome with new roof, entertaining spaces, and modern features.

    419 Cambridge Pl, Prince Frederick, MD 20678
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    New Townhome in Patuxent Commons
    $454,900

    New Townhome in Patuxent Commons

    Interior townhome with garage, deck, and modern features.

    84 Potomac Ct, Prince Frederick, MD 20678
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    Medical Office Condo For Sale
    Contact for pricing
    21,532 SF

    Medical Office Condo For Sale

    Medical office condo across from Calvert Health Medical Center.

    125 Stoakley Rd, Prince Frederick, MD 20678
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    Turnkey Daycare Business Opportunity
    $185,000

    Turnkey Daycare Business Opportunity

    Established daycare center, licensed for 40 children, ready for operation.

    270 Bugeye Sq, Prince Frederick, MD 20678
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    Professional Office Building For Sale
    $1,900,000

    Professional Office Building For Sale

    Fully leased professional office building near hospital, shopping, and restaurants.

    1020 Prince Frederick Blvd, Prince Frederick, MD 20678
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    Prince Frederick Specialty Property
    $385,000

    Prince Frederick Specialty Property

    Specialty property available for sale in Prince Frederick, MD.

    362 Cambridge Pl, Prince Frederick, MD 20678
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    Prince Frederick Specialty Property
    $649,900

    Prince Frederick Specialty Property

    Specialty property available for sale in Prince Frederick, MD.

    1940 Adelina Rd, Prince Frederick, MD 20678
    View details

    Prince Frederick, MD Commercial Real Estate Leasing Opportunities Market Analysis

    Explore Commercial Real Estate leasing options in Prince Frederick, MD with 37 listings featured on our commercial real estate exchange. The current inventory includes 924,517,440 square feet of properties with an estimated lease value of $78 SF/Yr.

    Estimated lease rates for Commercial Real Estate in Prince Frederick, MD begin at $18 SF/Yr, with an average of $26 SF/Yr and extend to $40 SF/Yr.

    In Prince Frederick, MD, current lease rates show:

    • Other retail properties positioned at $29
    • Retail properties measuring $29
    • Healthcare properties assessed at $20
    • Medical offices calculated at $20
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    Browse Commercial real estate for Lease Near Prince Frederick, MD

    Popular Searches in Prince Frederick, MD

    Most Searched ZIP Codes in Prince Frederick, MD

    • 20678

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