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Manlius, NY Commercial Land for Sale

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Vacant Land on Syracuse Eastside
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Vacant Land on Syracuse Eastside

Medical Center Drive, Manlius, NY 13066

3.85 acres of vacant land with development potential.

  • Subdivision and site plan approval in place for a single story 35,000 sf 66‑bed memory care facility.
  • Versatile zoning permits residential, medical, professional office, private schools, places of worship.
  • All utilities, water & sewer are available at the site.
  • Located on Syracuse's east side on 3.85 acres.
  • Close proximity to shopping, major roadways and daily needs.
Updated: Nov 25, 2025
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Based on your search, we've compiled 29 Potential Opportunities for your consideration. Besides 1 Active listings in Manlius, NY, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 24 Off-Market properties to explore as potential leads

Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Vacant Land in Retail Hub
$3,500,000
5.60 Acres

Vacant Land in Retail Hub

5.6 AC vacant land suitable for retail or mixed-use development.

5814 Bridge St, East Syracuse, NY
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Fayetteville Land for Office Space
$625,000

Fayetteville Land for Office Space

1.5 acre site suitable for office development in Fayetteville.

Medical Center Dr, Fayetteville, NY 13066
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Fayetteville Land for Office Space
$625,000

Fayetteville Land for Office Space

1.5 acre site suitable for office development.

Medical Center Dr, Fayetteville, NY 13066
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Shovel Ready Land Available
$3,000,000

Shovel Ready Land Available

5.28 acres of land with utilities and highway access.

5855 Widewaters Pkwy, East Syracuse, NY 13057
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Explore Off-Market Properties in Manlius, NY

Consider similar Off-Market properties in Manlius, NY. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

4819 Sweet Rd

4819 Sweet Rd

VACANT COMMERCIAL LAND • 3.42 Acres
Value Estimation by Request
4819 Sweet Rd, Manlius, NY 13104-1415
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4581 Enders Rd

4581 Enders Rd

VACANT COMMERCIAL LAND • 1.78 Acres
Value Estimation by Request
4581 Enders Rd, Manlius, NY 13104-9748
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314 Fayette St

314 Fayette St

VACANT COMMERCIAL LAND • 27,731 SF
Value Estimation
$1,950,000
314 Fayette St, Manlius, NY 13104-1609
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Manlius Cazenovia Rd

Manlius Cazenovia Rd

VACANT COMMERCIAL LAND • 0.65 Acres
Value Estimation by Request
Manlius Cazenovia Rd, Manlius, NY 13104
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117 Seneca St

117 Seneca St

VACANT COMMERCIAL LAND • 0.29 Acres
Value Estimation by Request
117 Seneca St, Manlius, NY 13104-1833
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4500 Pewter Ln

4500 Pewter Ln

VACANT COMMERCIAL LAND • 3,096 SF
Value Estimation by Request
4500 Pewter Ln, Manlius, NY 13104-9725
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106 Smith St

106 Smith St

VACANT COMMERCIAL LAND • 0.23 Acres
Value Estimation by Request
106 Smith St, Manlius, NY 13104-1822
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4500 Pewter Ln

4500 Pewter Ln

VACANT COMMERCIAL LAND • 3.27 Acres
Value Estimation by Request
4500 Pewter Ln, Manlius, NY 13104-9725
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116 Seneca St

116 Seneca St

VACANT COMMERCIAL LAND • 1.03 Acres
Value Estimation by Request
116 Seneca St, Manlius, NY 13104
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Willowbrook Ln

Willowbrook Ln

VACANT COMMERCIAL LAND • 11.89 Acres
Value Estimation by Request
Willowbrook Ln, Manlius, NY 13104
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102 Washington St

102 Washington St

VACANT COMMERCIAL LAND • 4.05 Acres
Value Estimation by Request
102 Washington St, Manlius, NY 13104-1913
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Thermold Dr

Thermold Dr

VACANT COMMERCIAL LAND • 0.15 Acres
Value Estimation by Request
Thermold Dr, Manlius, NY 13104
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Sweet Rd

Sweet Rd

VACANT COMMERCIAL LAND • 72.13 Acres
Value Estimation by Request
Sweet Rd, Manlius, NY 13104
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89 Stickley Dr

89 Stickley Dr

VACANT COMMERCIAL LAND • 0.74 Acres
Value Estimation by Request
89 Stickley Dr, Manlius, NY 13104
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Seneca Tpke

Seneca Tpke

VACANT COMMERCIAL LAND • 12.74 Acres
Value Estimation by Request
Seneca Tpke, Manlius, NY 13104
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228 Seneca St

228 Seneca St

VACANT COMMERCIAL LAND • 0.02 Acres
Value Estimation by Request
228 Seneca St, Manlius, NY 13104-1818
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Highbridge Rd

Highbridge Rd

VACANT COMMERCIAL LAND • 0.05 Acres
Value Estimation by Request
Highbridge Rd, Manlius, NY 13104
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Glencliffe Rd

Glencliffe Rd

VACANT COMMERCIAL LAND • 39.03 Acres
Value Estimation by Request
Glencliffe Rd, Manlius, NY 13104
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Garrett Dr

Garrett Dr

VACANT COMMERCIAL LAND • 0.14 Acres
Value Estimation by Request
Garrett Dr, Manlius, NY 13104
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106 Franklin St

106 Franklin St

VACANT COMMERCIAL LAND • 0.26 Acres
Value Estimation by Request
106 Franklin St, Manlius, NY 13104-1806
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113 Fairgrounds Dr

113 Fairgrounds Dr

VACANT COMMERCIAL LAND • 0.31 Acres
Value Estimation by Request
113 Fairgrounds Dr, Manlius, NY 13104-2416
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Fairgrounds Dr

Fairgrounds Dr

VACANT COMMERCIAL LAND • 0.73 Acres
Value Estimation by Request
Fairgrounds Dr, Manlius, NY 13104
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Eureka Dr

Eureka Dr

VACANT COMMERCIAL LAND • 0.71 Acres
Value Estimation by Request
Eureka Dr, Manlius, NY 13104
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Manlius, NY Commercial Land Investment Opportunities Market Analysis

Explore 25 commercial land for sale in Manlius, NY on our real estate platform. These investment opportunities span a total of 6,785,776 square feet of properties for sale, with an estimated market value of $1,500,000.

Sale prices for commercial lots in Manlius, NY start at $0.00, averaging $57,692, and reaching up to $1,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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