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Chicago, IL Medical Space for Lease

27 results
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West Town Storefront with Clinical Build-Out
$19 SF/Yr

West Town Storefront with Clinical Build-Out

1638 W Chicago Ave, Chicago, IL 60622

B1-2 zoned storefront ideal for med-spa or therapy practices.

  • B1‑2 Zoned Storefront with Existing Clinical Infrastructure: Ideal for various medical or beauty practices.
  • Two Plumbed 'Wet Rooms' with Sinks & a Private Shower: Ready for esthetician, med‑spa, or therapy use.
  • Recently Updated Dual‑Zone HVAC System: Ensures climate control and comfort.
  • Prime West Town Location: Situated in a high‑traffic commercial area.
  • Eligible for West Town SSA #29 Rebates: Funding available for signage, security, and facade improvements.
Last Update: Dec 9
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Pilsen Retail Storefront on 18th
$29 SF/Yr

Pilsen Retail Storefront on 18th

1102 W 18Th St, Chicago, IL 60608

Premier 1,500 SF retail space in historic Pilsen corridor.

  • Prime location on Pilsen's historic 18th Street Corridor with high foot traffic and strong community engagement.
  • 1,500 SF flagship retail space with exceptional visibility, expansive all‑glass facade, and approximately twelve‑foot ceilings.
  • Additional ~816 SF of usable lower‑level space for storage, office, or back‑of‑house operations.
  • Flexible, open layout suitable for a wide range of businesses including retail, healthcare, fitness, hospitality, and creative concepts.
  • Located in a growing trade area (ZIP code 60608) with a large population, rising incomes, and proximity to UIC and the Illinois Medical District.
Last Update: Dec 2
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High-Traffic Retail/Office/Medical Space Available
$25 SF/Yr

High-Traffic Retail/Office/Medical Space Available

Renovated space suitable for retail, office, or medical use.
1325 W Wilson Ave, Chicago, IL 60640
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Lincoln Park Luxe Soft Loft
$31 SF/Yr

Lincoln Park Luxe Soft Loft

Light-filled loft ideal for professional office or health and wellness.
1113 W Armitage Ave, Chicago, IL 60614
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River North Multi-Use Space
$35 SF/Yr

River North Multi-Use Space

Versatile space in River North, suitable for office, retail, or medical.
16 W Ontario St, Chicago, IL 60654
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River North Versatile Space For Rent
$35 SF/Yr

River North Versatile Space For Rent

Multi-room space in River North suitable for various businesses.
16 W Ontario St, Chicago, IL 60654
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Milwaukee Avenue Private Suite
$117 SF/Yr

Milwaukee Avenue Private Suite

Private suite ideal for licensed professionals in Logan Square.
2839 N Milwaukee Ave, Chicago, IL 60618
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Evergreen Park Retail Flex Space
$15 SF/Yr

Evergreen Park Retail Flex Space

Retail flex space available for lease in Evergreen Park.
10224 S Kedzie Ave, Evergreen Park, IL 60805
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Turnkey Medical Office in Gold Coast
$41 SF/Yr

Turnkey Medical Office in Gold Coast

4,400 SF medical office space for lease in Chicago's Gold Coast.
33 W Delaware Pl, Chicago, IL 60610
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Prime Retail Space, South Shore
$12 SF/Yr
12,000 SF

Prime Retail Space, South Shore

12,000 SF, High-Visibility Location
2015 79Th St, Chicago, IL 60649
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Printer's Row Retail Space Available
Contact for pricing
1,915 SF

Printer's Row Retail Space Available

1915 sq ft Retail Space - Prime Location
642 Clark St, Chicago, IL 60605
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Millennium Station Retail/Office/Medical Space
$70 SF/Yr

Millennium Station Retail/Office/Medical Space

Storefront retail, office, or medical spaces in Millennium Station.
151 N Michigan Ave, Chicago, IL 60602
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Prime Retail Space on Belmont
$35 SF/Yr

Prime Retail Space on Belmont

High-traffic retail space with excellent street exposure and flexible usage.
906 W Belmont Ave, Chicago, IL 60657
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New Retail Spaces on Lincoln
$30 SF/Yr

New Retail Spaces on Lincoln

New construction retail/office/medical spaces in North Center near public transit.
3914 N Lincoln Ave, Chicago, IL 60613
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Available Storefronts North of Irving
$20 SF/Yr

Available Storefronts North of Irving

Three storefronts available for lease in a local business corridor.
4075 N Broadway St, Chicago, IL 60613
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Versatile Storefront with Medical Amenities
$15 SF/Yr

Versatile Storefront with Medical Amenities

Adaptable storefront, previously a doctor's office, suitable for various businesses.
3215 W Cermak Rd, Chicago, IL 60623
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Renovated Gold Coast Retail/Office Space
$24 SF/Yr

Renovated Gold Coast Retail/Office Space

Recently renovated retail or office space in Gold Coast location.
1221 N La Salle St, Chicago, IL 60610
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West Town/Kinzie Corridor Office Space
$12 SF/Yr

West Town/Kinzie Corridor Office Space

Economical office and lab spaces available for lease.
2450 W Hubbard St, Chicago, IL 60612
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Division Street Commercial Condo for Lease
$21 SF/Yr

Division Street Commercial Condo for Lease

Ground-floor commercial condo in Old Town, ideal for various uses.
511 W Division St, Chicago, IL 60610
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Turnkey Retail/Office Space Available
$27 SF/Yr
1,290 SF

Turnkey Retail/Office Space Available

1,290 SF retail/office space in a high-visibility location.
2040 W Belmont Ave, Chicago, IL 60657
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Retail Space Near Loyola Campus
Contact for pricing
160,008 SF

Retail Space Near Loyola Campus

Storefront in a 152-unit building near Loyola University.
6466 N Sheridan Rd, Chicago, IL 60626
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Medical and Spa Space Available
Contact for pricing
1,836 SF

Medical and Spa Space Available

Second-generation medical and spa spaces in a high-traffic location.
730 N La Salle Dr, Chicago, IL 60654
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Retail Space Near Loyola Campus
$28 SF/Yr
5,838 SF

Retail Space Near Loyola Campus

Retail space near Loyola's Rogers Park campus, high visibility.
6418-6438 N Sheridan Rd, Chicago, IL 60613
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Medical/Retail Space Near Rush Hospital
Contact for pricing
900 SF

Medical/Retail Space Near Rush Hospital

Located in Illinois Medical District near hospitals and transportation.
1438-1550 W Harrison St, Chicago, IL 60607
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Chicago, IL Medical space Leasing Opportunities Market Analysis

Explore Medical space leasing options in Chicago, IL with 38 listings featured on our commercial real estate exchange. The current inventory includes 1,116,617,040 square feet of properties with an estimated lease value of $114 SF/Yr.

Estimated lease rates for Medical space in Chicago, IL begin at $12 SF/Yr, with an average of $22 SF/Yr and extend to $28 SF/Yr.
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