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Anderson, SC Commercial Real Estate for Sale

277 results
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Versatile Commercial Space, Anderson SC
$685,000
7,200 SF

Versatile Commercial Space, Anderson SC

405 Pearman Dairy Rd, Anderson, SC 29625

Expansive commercial property with high visibility and traffic.

  • Prime location with high traffic count and incredible visibility.
  • Expansive 7,200+ square feet of versatile space suitable for various businesses.
  • Customizable open floor plan due to metal truss roofing.
  • Large garage/warehouse space with roll‑up door for easy deliveries and storage.
  • Ample parking for customers and staff.
Updated: Feb 18
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Downtown Anderson Multi-Use Commercial Property
$500,000
0.81 Acres

Downtown Anderson Multi-Use Commercial Property

202-208 W Franklin St, Anderson, SC 29624

Turnkey facility with convenience store, restaurant, bar, and event center.

  • Turnkey multi‑use commercial property with Convenience Store, Restaurant/Ice Cream Shoppe, Bar, and Event Center.
  • Recent major renovations: New Roof, New Electric, New AC, New Lighting, and New Ceiling.
  • Located in a high‑growth zone of Downtown Anderson with massive upside potential.
  • High‑visibility location in the path of progress.
  • Situated to serve the growing population of young professionals and families.
Updated: Dec 10, 2025
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Move-In Ready Office Suite
$190,000

Move-In Ready Office Suite

Professional office suite near hospital with high traffic and signage.

400 N Fant St, Anderson, SC 29621
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High-Traffic Commercial Land Available
$585,000
1.45 Acres

High-Traffic Commercial Land Available

1.45 acre commercial land with high visibility and accessibility.

Destination Blvd, Anderson, SC 29621
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High-Traffic Commercial Land Available
$585,000
4.61 Acres

High-Traffic Commercial Land Available

4.61 acres at I-85 and US 76-28 intersection.

lot R-1-B R-2 Destination Blvd, Anderson, SC 29621
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Prime Commercial Land I-85 Frontage
$949,000
1.80 Acres

Prime Commercial Land I-85 Frontage

High-traffic commercial land with utilities ready for development near I-85.

105 Destination Blvd, Anderson, SC 29621
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Versatile Mixed-Use Commercial Property
$750,000
0.48 Acres

Versatile Mixed-Use Commercial Property

Over 5,000 sq ft commercial property with residential area.

4327 Old Mill Rd, Anderson, SC 29623
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Charming Office Space Near Downtown
$225,000
1,400 SF

Charming Office Space Near Downtown

Office cottage near downtown Anderson, close to amenities.

609 Bonham Ct, Anderson, SC 29621
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Highway 81 Commercial Lot
$409,000
0.98 Acres

Highway 81 Commercial Lot

Prime 0.98-acre commercial lot on Highway 81 North.

00 Highway 81 N, Anderson, SC 29621
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Versatile Retail Space Near Downtown
$275,000
0.28 Acres

Versatile Retail Space Near Downtown

Adaptable commercial property near downtown Anderson, South Carolina.

1804 S Mcduffie St, Anderson, SC 29624
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Cleared Land Near Clemson Boulevard
$650,000
7.50 Acres

Cleared Land Near Clemson Boulevard

7.5 acres of cleared, fenced land with warehouse buildings.

1009 Whitehall Rd, Anderson, SC 29625
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Commercial Property in High-Traffic Location
$75,000
0.41 Acres

Commercial Property in High-Traffic Location

Prime commercial property suitable for service-based businesses or redevelopment.

207 Manley Dr, Anderson, SC 29626
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Prime Land Near Technical College
$975,000
4.53 Acres

Prime Land Near Technical College

4.53-acre commercial land with highway frontage near Tri-County Technical College.

321 Pearman Dairy Rd, Anderson, SC 29625
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Historic Restaurant Space in Anderson
$2,250,000
0.38 Acres

Historic Restaurant Space in Anderson

Turnkey restaurant in historic downtown Anderson with prime real estate value.

116 W Orr St, Anderson, SC 29625
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Commercial Land in Anderson, SC
$585,100
4.61 Acres

Commercial Land in Anderson, SC

4.61 acres of commercial land for sale in Anderson.

R-2 Destination Blvd, Anderson, SC 29621
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Versatile Residential Office Space
$439,900

Versatile Residential Office Space

Spacious property with living and office space, rental potential.

510 E Calhoun St, Anderson, SC 29621
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Anderson Automotive Garage with Living Space
$485,000
4,290 SF

Anderson Automotive Garage with Living Space

Automotive garage with living space in thriving Anderson, South Carolina.

609 Fair St, Anderson, SC 29625
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Industrial Building on 50 Acres
$2,250,000
27,000 SF

Industrial Building on 50 Acres

27,000 sqft industrial building on 50 acres near Lake Hartwell.

5575 Dobbins Bridge Rd, Anderson, SC 29626
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Spacious Home on 31 Acres
$1,399,999
4,000 SF

Spacious Home on 31 Acres

31 acre property with 5-bedroom home, barn, and pastures.

265 Gibson Rd, Anderson, SC 29625
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Commercial Lot in Mall Park
Contact for pricing
0.15 Acres

Commercial Lot in Mall Park

Centrally located commercial lot among established businesses in Anderson, SC.

29 Civic Center Boulevard Ext, Anderson, SC 29625
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Corner Lot Near Downtown Anderson
$79,900
0.24 Acres

Corner Lot Near Downtown Anderson

Desirable corner lot near downtown Anderson, zoned for general commercial.

1002 S Main St, Anderson, SC 29624
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Solid Building on South Main
$378,000

Solid Building on South Main

Renovated building suitable for retail or special purposes.

711 S Main St, Anderson, SC 29624
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Office Space in Anderson, SC
Contact for pricing
1.00 Acre

Office Space in Anderson, SC

Office property for sale in Anderson, South Carolina.

2315 N Main St, Anderson, SC 29621
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Commercial Land in Anderson, SC
$949,000
1.80 Acres

Commercial Land in Anderson, SC

1.8 acre commercial site available in Anderson, South Carolina.

105 Destination Blvd, Anderson, SC 29621
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Anderson, SC Commercial Real Estate Investment Opportunities Market Analysis

Explore 166 commercial real estate for sale in Anderson, SC, showcased through 277 active listings on our real estate platform. These investment opportunities span a total of 121,017,303 square feet of properties for sale, with an estimated market value of $69,051,956.

Sale prices for business properties in Anderson, SC start at $35,000, averaging $852,493, and reaching up to $8,379,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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