Panama City, FL Commercial real estate for Rent & Lease

Unique Commercial Property in Panama City

$5,000 / Mo

1,708 SF

Unique Commercial Property in Panama City

854 Magnolia Ave, Panama City, FL 32401

Custom mixed-use property with luxury finishes and multiple entrances.

Mixed‑Use Zoning allows for multiple commercial uses.
Large Half‑Acre Lot provides ample space for expansion.
Two Large Suites with Private Entrances each featuring a gas fireplace, walk‑in closet, and custom bathroom.
Newly Remodeled with Modern Amenities including refinished wood floors, a modern kitchen with quartz countertops and stainless steel appliances, built‑in speakers, and security/Nest systems.
Prime Location in the heart of historic Panama City, minutes from the revitalized downtown area.

Updated: Mar 13

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Versatile Commercial Building on Highway 77

$5,000 / Mo

4,814 SF

Versatile Commercial Building on Highway 77

13919 Highway 77, Panama City, FL 32409

4,800 SF steel building on 1.24 acres with frontage.

High‑visibility location on rapidly growing Hwy 77.
4,800 SF steel building on 1.24 acres with ample parking and easy trailer access.
Equipped with commercial‑grade septic system for a restaurant, existing kitchen hood range, and drive‑through setup.
Dedicated ingress/egress right on State Hwy 77.
Located near a 140‑home community under construction.

Updated: Feb 18

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$21 SF/Yr

1,906 SF

Downtown Panama City Office Space

Professional office space in downtown Panama City for lease.

455 Harrison Ave, Panama City, FL 32401

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$24 SF/Yr

51,876 SF

Retail Space in Panama City

Retail space available for lease in Panama City, Florida.

133 S Tyndall Pkwy, Panama City, FL 32404

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$16 SF/Yr

51,876 SF

Retail Center in Panama City

Retail space available in Panama City, Florida.

133 S Tyndall Pkwy, Panama City, FL 32404

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$21 SF/Yr

51,876 SF

Retail Center in Panama City

Retail spaces available in upcoming Panama City shopping center.

133 S Tyndall Pkwy, Panama City, FL 32404

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$24 SF/Yr

51,876 SF

Retail Space in Panama City

Retail space available for lease in Panama City, Florida.

133 S Tyndall Pkwy, Panama City, FL 32404

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$3,500 / Mo

6,500 SF

Versatile Commercial Space Off Highway

Flexible leasing options near Highway 231, ideal for various businesses.

6804 Bayou George Dr, Panama City, FL 32404

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$12 SF/Yr

51,876 SF

Retail Center in Panama City

52,000 SF retail center, opening Spring 2027.

133 S Tyndall Pkwy, Panama City, FL 32404

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$22 SF/Yr

51,896 SF

Retail Center in Panama City

Retail spaces available in Panama City, FL, opening Spring 2027.

133 S Tyndall Pkwy, Panama City, FL 32404

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$2,500 / Mo

1,903 SF

Panama City Office Space Available

Well-located office building ideal for small businesses or professional services.

309 E 7Th St, Panama City, FL 32401

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$7,250 / Mo

2,418 SF

Panama City Beach Commercial Property

Commercial property in high-traffic area, previously a residential treatment center.

9719 Thomas Dr, Panama City, FL 32408

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$3,500 / Mo

1,800 SF

Unique Mixed-Use Property For Rent

Custom property with modern amenities, suitable for commercial or residential use.

5045 Highway 98 E, Panama City, FL 32404

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$15 SF/Yr

17,577 SF

Retail Space in Panama City

Open span retail space with office, breakroom, and bathrooms.

401 E 23Rd St, Panama City, FL 32405

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$3,700 / Mo

121,968 SF

Cleared Commercial Land For Lease

2.8 acres of vacant commercial land available for lease.

2110 Industrial Dr, Panama City, FL 32405

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$5,000 / Mo

Versatile Office and Warehouse Space

Versatile office and warehouse space in an ideal location.

1337 W 19Th St, Panama City, FL 32405

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$28 SF/Yr

Versatile Commercial Space Near Hospital

Class A commercial spaces for medical, office, fitness, or retail.

2402 State Ave, Panama City, FL 32405

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$24 SF/Yr

51,876 SF

Retail Space with Drive-Thru

Retail space available for lease with drive-thru.

133 S Tyndall Pkwy, Panama City, FL 32404

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$24 SF/Yr

51,876 SF

Retail Space in Panama City

Retail space for lease in Panama City, Florida.

133 S Tyndall Pkwy, Panama City, FL 32404

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$8,500 / Mo

8,464 SF

Downtown Panama City Warehouse Complex

Downtown Panama City warehouse complex with flexible leasing options.

733 Mulberry Ave, Panama City, FL 32401

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$25 SF/Yr

Equipped Medical Office Space Available

Ready-to-use medical office suite near HCA Florida Gulf Coast Hospital.

2426 Jenks Ave, Panama City, FL 32405

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$5,000 / Mo

4,814 SF

Highway 77 Commercial Opportunity

Versatile 4,800 SF building on 1.24 acres for rent.

13919 Highway 77, Panama City, FL 32409

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$12 SF/Yr

51,876 SF

Retail Center Under Construction

52,000 SF retail center with industrial potential.

133 S Tyndall Pkwy, Panama City, FL 32404

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Explore Similar Spaces for Sale in Panama City, FL

Consider Similar Space for Sale. We found 443 Spaces in Nearby Locations matching your search parameters.

High-Visibility Commercial Building on Corner Lot

$379,900

2,768 SF

High-Visibility Commercial Building on Corner Lot

2,768 SF commercial building on 0.446-acre corner lot.

247 Highway 22 A, Panama City, FL 32404

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Panama City, FL Commercial real estate Leasing Opportunities Market Analysis

Explore Commercial real estate leasing options in Panama City, FL with 615 listings featured on our commercial real estate exchange. The current inventory includes 111,767,511,240 square feet of properties with an estimated lease value of $2,109 /Mo.

Estimated lease rates for Commercial real estate in Panama City, FL begin at $0.55 SF/Yr, with an average of $17 SF/Yr and extend to $44 SF/Yr.

Panama City, FL Commercial Real Estate for Lease

Unique Commercial Property in Panama City

Custom mixed-use property with luxury finishes and multiple entrances.