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    Rancho Santa Margarita, CA Commercial Real Estate for Lease

    19 results
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    Koll Center
    Contact for pricing

    Koll Center

    All-inclusive access to workspace, virtual office and meeting rooms in O'Hare Airport

    30211 Avenida De Las Banderas, Rancho Santa Margarita, CA 92688
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    Turnkey Office/Warehouse Condo Sublease
    $4,100 / Mo
    1,830 SF

    Turnkey Office/Warehouse Condo Sublease

    23121 Antonio Pkwy, Rancho Santa Margarita, CA 92688

    Upgraded 1,830 SF office/warehouse condo in Rancho Santa Margarita.

    • Turnkey office/warehouse condo: Move‑in ready, minimizing downtime.
    • 1,830 SF: Balanced space for office and warehouse operations.
    • High‑end finishes: Presents a polished and professional image.
    • Desirable Rancho Santa Margarita location: Situated in a sought‑after business park.
    • Combines office and warehouse: Integrates professional office space with functional warehouse capabilities.
    Updated: Dec 18, 2025
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    Rancho Santa Margarita Multi-Tenant Center
    Contact for pricing
    8,500 SF

    Rancho Santa Margarita Multi-Tenant Center

    29821-29941 Aventura, Rancho Santa Margarita, CA 92688

    Retail, office, and medical spaces in Rancho Santa Margarita.

    • Strategically located off the 241 Toll Road, at the gateway of Rancho Santa Margarita
    • United States Postal Service is the driver of the center
    • Excellent daytime population from adjacent business parks
    • One of the strongest income demographics in Orange County
    • Excellent center to gain a foothold in this high demand trade area
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    Office Building with Mountain Views
    $2 SF/Yr
    18,538 SF

    Office Building with Mountain Views

    Two-story office building in South Orange County available for rent.

    22362 Gilberto, Rancho Santa Margarita, CA 92688
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    Medical Office Condo For Rent
    $2 SF/Yr
    2,360 SF

    Medical Office Condo For Rent

    Medical office condo featuring private offices, conference room, and balcony.

    30212 Tomas, Rancho Santa Margarita, CA 92688
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    Rancho Santa Margarita Retail Center
    Contact for pricing

    Rancho Santa Margarita Retail Center

    275,000 SF power center with excellent visibility and access.

    30451-30465 Avenida De Las Flores, Rancho Santa Margarita, CA 92688
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    Restaurant Spaces in Rancho Santa Margarita
    Contact for pricing

    Restaurant Spaces in Rancho Santa Margarita

    Restaurant spaces for lease in Rancho Santa Margarita shopping center.

    31431-31541 Santa Margarita Pkwy, Rancho Santa Margarita, CA 92688
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    Retail Space in South Orange
    $2 SF/Yr
    87,715 SF

    Retail Space in South Orange

    Prime South Orange County retail space available for lease.

    29851 Aventura, Rancho Santa Margarita, CA 92688
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    Freestanding R&D Building For Lease
    $1.65 SF/Yr
    18,112 SF

    Freestanding R&D Building For Lease

    Two-story R&D building with secured yard in South Orange County.

    22391 Gilberto, Rancho Santa Margarita, CA 92688
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    Rancho Santa Margarita Flex Space
    $1.70 SF/Yr
    5,583 SF

    Rancho Santa Margarita Flex Space

    Flex space with offices, kitchen, fenced yard, and ample power.

    30302 Esperanza, Rancho Santa Margarita, CA 92688
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    Industrial Warehouse with Fenced Yard
    $1.58 SF/Yr
    10,030 SF

    Industrial Warehouse with Fenced Yard

    Industrial warehouse featuring a fenced yard and major street frontage.

    29720 Avenida De Las Banderas, Rancho Santa Margarita, CA 92688
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    High-Image Flex Building For Rent
    $1.45 SF/Yr
    23,849 SF

    High-Image Flex Building For Rent

    R&D/flex building in South Orange County business park.

    30191 Avenida De Las Banderas, Rancho Santa Margarita, CA 92688
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    Industrial Building with Gated Yard
    $1.55 SF/Yr
    20,500 SF

    Industrial Building with Gated Yard

    Freestanding industrial building featuring office space and a gated yard.

    30412 Esperanza, Rancho Santa Margarita, CA 92688
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    Freestanding Building with Extensive Glass
    $500 / Mo
    5,810 SF

    Freestanding Building with Extensive Glass

    Single-story industrial building with excellent freeway access and retail proximity.

    23142 Arroyo Vis, Rancho Santa Margarita, CA 92688
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    Rancho Santa Margarita Warehouse Space
    Contact for pricing

    Rancho Santa Margarita Warehouse Space

    Warehouse space with air conditioning and easy transportation access.

    22412 Gilberto, Rancho Santa Margarita, CA 92688
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    Rancho Santa Margarita Office Building
    Contact for pricing
    8,309 SF

    Rancho Santa Margarita Office Building

    Office building available, early education/school permitted.

    28672 Deerpath, Rancho Santa Margarita, CA 92688
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    Industrial Property in Rancho Santa Margarita
    Contact for pricing

    Industrial Property in Rancho Santa Margarita

    100% leased industrial property with no current availability.

    22321 Gilberto, Rancho Santa Margarita, CA 92688
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    Rancho Santa Margarita Office Space
    $42 SF/Yr
    87,331 SF

    Rancho Santa Margarita Office Space

    Prime Orange County Office Suites Available

    29821-29941 Aventura, Rancho Santa Margarita, CA 92688
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    Regus Koll Center: Rancho Santa Margarita
    $22 SF/Yr
    20,508 SF

    Regus Koll Center: Rancho Santa Margarita

    Prime Orange County Office Space

    30211 Avenida De Las Banderas, Rancho Santa Margarita, CA 92688
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    Based on your search, we've compiled 26 Potential Opportunities for your consideration. Besides 19 Active listings in Rancho Santa Margarita, CA, we suggest exploring alternatives. Similar 7 Properties for Sales.

    Explore Similar Spaces for Sale in Rancho Santa Margarita, CA

    Consider Similar Space for Sale. We found 7 Spaces in Nearby Locations matching your search parameters.

    Upgraded Office Condo For Sale
    $1,706,300
    3,020 SF

    Upgraded Office Condo For Sale

    Office condo with private offices, conference room, and break room.

    30372 Esperanza, Rancho Santa Margarita, CA 92688
    View details
    Freestanding Medical Office Building For Sale
    $3,645,600
    6,076 SF

    Freestanding Medical Office Building For Sale

    Single-story medical office building with Santa Barbara style architecture.

    29803 Santa Margarita Pkwy, Rancho Santa Margarita, CA 92688
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    Upgraded Office in Prime Location
    $6,950,000
    21,810 SF

    Upgraded Office in Prime Location

    Highly upgraded office building with potential warehouse conversion.

    30242 Esperanza, Rancho Santa Margarita, CA 92688
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    Rancho Santa Margarita Warehouse
    Contact for pricing
    10,030 SF

    Rancho Santa Margarita Warehouse

    Warehouse with large fenced yard and freeway access available for sale.

    29702 Avenida De Las Bandera, Rancho Santa Margarita, CA 92688
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    Rancho Santa Margarita Religious Facility
    Contact for pricing
    4,868 SF

    Rancho Santa Margarita Religious Facility

    4,868 SF religious facility on 2.4 acres for sale.

    30605 Avenida De Las Flores, Rancho Santa Margarita, CA 92688
    View details

    Rancho Santa Margarita, CA Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Rancho Santa Margarita, CA with 26 listings featured on our commercial real estate exchange. The current inventory includes 13,162,350,960 square feet of properties with an estimated lease value of $106 SF/Yr.

    Estimated lease rates for Commercial real estate in Rancho Santa Margarita, CA begin at $1.03 SF/Yr, with an average of $8 SF/Yr and extend to $42 SF/Yr.
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