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Holyoke, MA Commercial Real Estate for Lease

39 results
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Versatile Commercial Space in Holyoke
$10 SF/Yr
17,990 SF

Versatile Commercial Space in Holyoke

107 Lyman St, Holyoke, MA 01040

Centrally located commercial building in downtown Holyoke with flexible lease terms.

  • Prime downtown Holyoke location between two scenic water canals.
  • Opportunity to customize space in a major remodel, shaping your ideal business environment.
  • Flexible lease terms and gross leases starting at $10/sq.ft.
  • Versatile zoning: Office, warehouse, and light industrial.
  • Included utilities: Heat, water, and on‑site dumpster.
Updated: Jul 4, 2025
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Holyoke Basement Retail Space Available
$2,500 / Mo

Holyoke Basement Retail Space Available

301 High St, Holyoke, MA 01040

4,000 SF basement space for creative vision in Holyoke.

  • Approximately 4,000 sf basement space.
  • $2,500 + utilities rental cost.
  • Versatile space suitable for custom buildouts.
  • Located in a mixed‑use building.
  • Building dating back to 1880.
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Office Space in Holyoke, MA
$18 SF/Yr
3,750 SF

Office Space in Holyoke, MA

Office space for lease in Holyoke, Massachusetts.

36-40 Bobala Rd, Holyoke, MA 01040
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Retail Space on High Street
$1,200 / Mo
1,030 SF

Retail Space on High Street

Retail space available for lease in Holyoke, Massachusetts.

141-147 High St, Holyoke, MA 01040
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Holyoke Flex Space For Rent
$12 SF/Yr

Holyoke Flex Space For Rent

Flexible industrial, creative, and office spaces available for rent.

81 Sargeant St, Holyoke, MA 01040
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Holyoke Retail/Office Space For Rent
$22 SF/Yr

Holyoke Retail/Office Space For Rent

1,012 SF retail/office space in high-traffic Holyoke location.

226-230 Sargeant St, Holyoke, MA 01040
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Holyoke Commercial Space For Rent
$14 SF/Yr

Holyoke Commercial Space For Rent

Commercial spaces available in Holyoke's vibrant business district.

103-109 High St, Holyoke, MA 01040
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Venue with Full Bar Buildout
$13 SF/Yr

Venue with Full Bar Buildout

Venue with full bar buildout and guest seating space.

106-120 High St, Holyoke, MA 01040
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Commercial Land with Drive-Thru Potential
Contact for pricing

Commercial Land with Drive-Thru Potential

0.75 acres permitted for 7,000 SF with drive-thru.

44 Holyoke St, Holyoke, MA 01040
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Holyoke Studio Space For Rent
$13 SF/Yr
29,981 SF

Holyoke Studio Space For Rent

Versatile 5,000 SF studio in Holyoke's creative community.

92 Race St, Holyoke, MA 01040
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Warehouse/Flex Building with Highway Access
$6 SF/Yr

Warehouse/Flex Building with Highway Access

Warehouse/flex building for lease with planned improvements and highway access.

158 Chestnut St, Holyoke, MA 01040
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Holyoke Mill Flex/Warehouse Spaces
$1.00 SF/Yr

Holyoke Mill Flex/Warehouse Spaces

Versatile industrial and creative spaces in historic Holyoke mill.

420 Dwight St, Holyoke, MA 01040
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Holyoke Warehouse Space for Lease
$1.45 SF/Yr

Holyoke Warehouse Space for Lease

110,000 SF industrial warehouse space available for lease.

475 Canal St, Holyoke, MA 01040
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Professional Office Space Available
Contact for pricing
2,000 SF

Professional Office Space Available

2,000 SF former medical office space for lease.

15 Main St, Holyoke, MA 01040
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Class A Office Space Available
Contact for pricing
4,280 SF

Class A Office Space Available

Executive office park with flexible floor plans and highway access.

330 Whitney Ave, Holyoke, MA 01040
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Retail Space in Holyoke Center
Contact for pricing
3,000 SF

Retail Space in Holyoke Center

Retail space available in a busy Holyoke shopping center.

2203-2295 Northampton St, Holyoke, MA 01040
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Industrial Space Available for Rent
$11 SF/Yr
416 SF

Industrial Space Available for Rent

416 square feet of industrial space for lease.

420-432 Race St, Holyoke, MA 01040
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Versatile Commercial Space for Rent
Contact for pricing

Versatile Commercial Space for Rent

Prime commercial space ideal for retail, office, or restaurant.

393 Main St, Holyoke, MA 01040
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Updated Mill Building for Lease
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Updated Mill Building for Lease

Four-story mill building with existing cannabis businesses and approved parking.

1 Cabot St, Holyoke, MA 01040
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Retail Space in Neighborhood Center
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8,952 SF

Retail Space in Neighborhood Center

Retail spaces available within a 90,000 SF neighborhood center.

209-239 South St, Holyoke, MA 01040
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Versatile Commercial Space Available
Contact for pricing
10,612 SF

Versatile Commercial Space Available

Commercial space for lease in a desirable location.

1594 Dwight St, Holyoke, MA 01040
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Holyoke Office Space Available
Contact for pricing
2,991 SF

Holyoke Office Space Available

Office space available for rent in Holyoke, Massachusetts.

850 High St, Holyoke, MA 01040
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Holyoke Office Space For Rent
Contact for pricing
10,000 SF

Holyoke Office Space For Rent

10,000 square feet of office space available for lease.

4 Open Square Way, Holyoke, MA 01040
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Office Space for Rent
$6 SF/Yr

Office Space for Rent

Office space available for rent at 514 Main St.

514 Main St, Holyoke, MA 01040
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Holyoke, MA Commercial real estate Leasing Opportunities Market Analysis

Explore Commercial real estate leasing options in Holyoke, MA with 94 listings featured on our commercial real estate exchange. The current inventory includes 20,484,394,920 square feet of properties with an estimated lease value of $132 SF/Yr.

Estimated lease rates for Commercial real estate in Holyoke, MA begin at $4 SF/Yr, with an average of $12 SF/Yr and extend to $18 SF/Yr.
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