56 Main Street, Poughkeepsie, NY 12601

Listing agent UMESH SHRESTHA

Listing office BHHS HUDSON VALLEY PROPERTIES H***@gmail.com Show Phone

Listing date Jan 18, 2026

Source Corcoran

Displayed information is deemed reliable but is not guaranteed and should be independently verified.

All listing content including descriptions, pricing, images are the copyrighted material of BHHS HUDSON VALLEY PROPERTIES

Report an issue

---

Overview

This Class A standalone professional/medical building is located directly across from the Poughkeepsie Metro-North Station and steps from the Hudson River waterfront. The two-story, single-tenant building offers approximately 2,600 SF of usable interior space and was fully renovated in 2020. The current lease expires April 30, 2026, but earlier occupancy may be arranged with a firm lease commitment. The turn-key layout includes 7 private exam rooms/offices (sinks in most rooms), two reception areas, a large conference or training room, and restrooms on both floors. The space benefits from excellent natural light throughout and is in excellent condition. It is well suited for medical, wellness, medi-spa, studio, or professional office use. A rare downtown feature is the 20+ private on-site parking spaces. The property has outstanding visibility with signage exposure to Route 9 and the Route 9 South ramp, plus strong commuter traffic. It is walkable to the waterfront park and surrounding downtown amenities. Town records reflect approximately 3,624 SF gross building area. The lease rate does not include utilities, property expenses, or building services.

Suggested Use

Restaurant Real Estate Agency Building Supply Spa & Massage Center Dental Office Law Firm Big Box & Wholesale Store Auto Repair Shop Hair Salon Nail Salon

Zoning and permitted uses should be independently verified with local authorities.

Similar Places Nearby

• Creature Comforts Animal Hospital, P.C. — 64 Pine St, Poughkeepsie, NY 12601

Location Insight

• Map
• Local Demand

City

Poughkeepsie

County

Dutchess

State

New York

Longitude

-73.9375

Latitude

41.7052

Nearby Similar for Lease

• 

  $2,500/Mo

  2,700 SF

  Prime Retail Space in Poughkeepsie

  Revitalized Poughkeepsie business district retail space for lease.

  200 Main Street, Poughkeepsie, NY 12601

  View Details
• 

  $2,000/Mo

  817 SF

  Urban-Chic Commercial Space Available

  Revitalized Poughkeepsie business district, loft-style, high-visibility storefront for rent.

  204 Main Street, Poughkeepsie, NY 12601

  View Details
• 

  $2,500/Mo

  2,400 SF

  Poughkeepsie Retail Opportunity Near College

  2,400 sq ft retail space near Vassar College.

  12 Fowler Avenue, Poughkeepsie, NY 12603

  View Details
• 

  $19 SF/Yr

  7,047 SF

  Poughkeepsie Commercial Space For Lease

  Flexible commercial spaces near MJN Convention Center, McCann Ice Arena.

  233-237 Main Street, Poughkeepsie, NY 12601

  View Details
• 

  $2,600/Mo

  1,100 SF

  Downtown Poughkeepsie Office Space

  Professional office suite in downtown Poughkeepsie with utilities included.

  55 Market, Poughkeepsie, NY 12601

  View Details
• 

  $1,900/Mo

  700 SF

  Renovated Office Space in Poughkeepsie

  Newly renovated office space in downtown Poughkeepsie for lease.

  55 Market, Poughkeepsie, NY 12601

  View Details
• 

  $1,150/Mo

  368 SF

  Poughkeepsie First-Floor Office Space

  Versatile 368 SF office space in prime Poughkeepsie location.

  53 Market Street, Poughkeepsie, NY 12601

  View Details
• 

  $1,100/Mo

  Poughkeepsie Office Space for Lease

  Office space with private entrance, parking, and convenient location.

  2038 New Hackensack Road, Poughkeepsie, NY 12603

  View Details
• 

  $1,150/Mo

  372 SF

  Poughkeepsie First-Floor Office Space

  Versatile 372 SF office space in prime Poughkeepsie location.

  53 Market Street, Poughkeepsie, NY 12601

  View Details
• 

  $5,200/Mo

  3,624 SF

  Poughkeepsie Professional/Medical Building for Lease

  Renovated professional/medical building near Metro-North with parking.

  56 Main St, Poughkeepsie, NY 12601

  View Details
• 

  $2,000/Mo

  817 SF

  Urban-Chic Commercial Space Available

  Revitalized Poughkeepsie business district storefront with high visibility.

  204 Main St Commercial, Poughkeepsie, NY 12601

  View Details
• 

  $2,500/Mo

  2,700 SF

  Poughkeepsie Retail Space Available

  2,700 SF retail space in revitalized business district.

  200 Main St, Poughkeepsie, NY 12601

  View Details

FAQs

What type of property is this?

Medical Office Space - Class A renovated building near Metro-North Station, suitable for various uses.

Where is this medical office space located?

The property is located at 56 Main Street Poughkeepsie, NY.

What is the lease rate?

The lease rate is $5,200 /Mo.

What are key features of this property?

This property features: Directly across from Poughkeepsie Metro‑North Station and steps from the Hudson River waterfront.; 20+ private on‑site parking spaces (rare downtown feature).; Fully renovated in 2020.