Add Listing
    For Sale
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Property Types
    • Retail
    • Office
    • Residential Income
    • Restaurants
    • Industrial
    • Mixed-Use
    • Hospitality
    • Health Care
    • Sports & Entertainment
    • Land
    • Agricultural
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Chillicothe, MO Commercial Real Estate for Sale

    10 results
    List
    Map
    Turnkey Restaurant with Banquet Room
    $285,000

    Turnkey Restaurant with Banquet Room

    609 Jackson St, Chillicothe, MO 64601

    Ready-to-operate restaurant with banquet room and additional lot.

    • Turnkey restaurant with seating for approximately 120 people
    • Includes a banquet room and additional lot in back
    • Fully equipped kitchen with 6‑burner stove, ovens, flat grill, charbroiler, fryers, steam table, and walk‑in cooler
    • Potential for a 1‑bedroom, 1‑bath apartment (approximately 1200 sq ft)
    • Includes essential restaurant equipment: dishwasher, freezers, ice machine, tables, booths, and chairs
    Updated: Dec 5, 2025
    View details
    Historic Chillicothe Commercial Building
    $165,000
    13,440 SF

    Historic Chillicothe Commercial Building

    614 Washington St, Chillicothe, MO 64601

    Three-story commercial building in Chillicothe's historic district.

    • High‑traffic location on Washington St. in Chillicothe's historic district.
    • Income‑generating ground level with 7 established businesses.
    • Large 3‑story building offering diverse development opportunities (Airbnb, lofts, apartments, businesses).
    • Excellent exposure to locals and visitors.
    • Convenient access to nearby parking.
    Updated: Jul 30, 2025
    View details
    Industrial Building with Wash Bay
    $399,000
    6,050 SF

    Industrial Building with Wash Bay

    6,050 SF commercial building with wash bay and equipment.

    530 Mccormick St, Chillicothe, MO 64601
    View details
    Chillicothe, MO Vacant Land
    $125,000
    1.20 Acres

    Chillicothe, MO Vacant Land

    1.2-acre leveled lot in established industrial park, construction-ready.

    630 Industrial Rd, Chillicothe, MO 64601
    View details
    Commercial Property on Highway 65
    $249,000

    Commercial Property on Highway 65

    Commercial property with office space, pole barn, and covered pad.

    1011 Washington St, Chillicothe, MO 64601
    View details
    Prime Farmland with Highway Frontage
    $3,967,000
    440.80 Acres

    Prime Farmland with Highway Frontage

    440.8 acre farm near Chillicothe, MO with income potential.

    Tbd Hwy 13, Chillicothe, MO 64601
    View details
    Versatile Industrial Space in Chillicothe
    $130,000

    Versatile Industrial Space in Chillicothe

    Light industrial space with cranes, drive-in doors, and office.

    309 Madison St, Chillicothe, MO 64601
    View details
    Commercial Land Near Highway 36
    $450,000
    3.50 Acres

    Commercial Land Near Highway 36

    3.5 acre commercial land suitable for highway-centric businesses.

    Us Hwy 36, Chillicothe, MO 64601
    View details
    Commercial Land Near Highway 36
    $450,000
    3.50 Acres

    Commercial Land Near Highway 36

    3.5 acre commercial land suitable for high-traffic ventures.

    Us Hwy 36, Chillicothe, MO 64601
    View details
    Chillicothe Multifamily Investment Opportunity
    Contact for pricing

    Chillicothe Multifamily Investment Opportunity

    Missouri Ave Duplex/Triplex, $15k

    603 Missouri Ave Ave, Chillicothe, MO 64601
    View details
    Based on your search, we've compiled 14 Potential Opportunities for your consideration. Besides 10 Active listings in Chillicothe, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Hale, MO Farm/Estate Auction
    $800,000
    160.00 Acres

    Hale, MO Farm/Estate Auction

    159.4 acre farm with tillable land and hunting potential.

    18687 Hwy, Hale, MO 64643
    View details
    Turnkey Commercial Building in Hale, MO
    $199,000
    4,320 SF

    Turnkey Commercial Building in Hale, MO

    Fully equipped commercial building with bar and kitchen for sale.

    219 Main St, Hale, MO 64643
    View details
    Versatile Trenton Property with Potential
    $99,900
    0.11 Acres

    Versatile Trenton Property with Potential

    Adaptable property suitable for residential, business, or live/work use.

    152 E 8Th St, Trenton, MO 64683
    View details
    Turnkey Tree Farm Estate
    $3,200,000
    660 SF

    Turnkey Tree Farm Estate

    Established tree farm on 117 acres with living quarters.

    732 Highway 6 W, Trenton, MO 64683
    View details

    Chillicothe, MO Commercial Real Estate Investment Opportunities Market Analysis

    Explore 10 commercial real estate for sale in Chillicothe, MO, showcased through 10 active listings on our real estate platform. These investment opportunities span a total of 19,585,447 square feet of properties for sale, with an estimated market value of $5,556,000.

    Sale prices for business properties in Chillicothe, MO start at $125,000, averaging $926,000, and reaching up to $3,967,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map

    Browse Commercial real estate for Sale Near Chillicothe, MO

    Popular Searches in Chillicothe, MO

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!